Neuroscience

Discovery of a new key player in long-term memory

A McGill-led multi-institutional research team has discovered that during memory consolidation, there are at least two distinct processes taking place in two different brain networks—the excitatory and inhibitory networks. ...

Neuroscience

How ApoE4 endangers the brain

Apolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients, including with polyunsaturated fatty acids—which are building blocks of the membranes surrounding ...

Oncology & Cancer

Chimeras offer a new way to study childhood cancers in mice

In a new paper published March 5 in the journal Cell Stem Cell, researchers in Whitehead Institute Member Rudolph Jaenisch's lab introduce a new way to model human neuroblastoma tumors in mice using chimeras—in this case, ...

Oncology & Cancer

Fibroblasts involved in healing spur tumor growth in cancer

The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the site of a wound, instigating an inflammatory response that mends damaged tissue.

Medical research

New drug target discovered for the lung disease PAH

Scientists have identified a molecular pathway that contributes to the development of pulmonary arterial hypertension (PAH), a severe, often fatal condition that has no cure.

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