Neuroscience

Researchers test meth-addicted rats in a rodent casino

(Medical Xpress)—The altered decision-making patterns associated with neuropsychiatric disorders such as substance addiction are well documented, but it is unclear whether this dysfunction is the result of preexisting conditions ...

Oncology & Cancer

Case study of rare nervous system tumor reveals hypermutation

While deadly, gliosarcomas are a rare central nervous system tumor often overshadowed in research by more common tumors. These sarcomas can occur either in the brain or the spine (the latter is much less common).

Oncology & Cancer

Searching for the 'signature' causes of BRCAness in breast cancer

Breast cancer cells with defects in the DNA damage repair-genes BRCA1 and BRCA2 have a mutational signature (a pattern of base swaps—e.g., Ts for Gs, Cs for As—throughout a genome) known in cancer genomics as "Signature ...

Neuroscience

Researchers define two categories of multiple sclerosis patients

There are approximately 400,000 people in the United States with multiple sclerosis. Worldwide, the number jumps to more than 2.1 million people. Rather than a one-size-fits-all approach to treating the millions with multiple ...

Oncology & Cancer

Future prostate cancer treatments might be guided by math

Scientists have designed a first draft of a mathematical model that someday could guide treatment decisions for advanced prostate cancer, in part by helping doctors predict how individual patients will respond to therapy ...

Medical research

Cancer stem cells made, not born

In cancer, tumors aren't uniform: they are more like complex societies, each with a unique balance of cancer cell types playing different roles. Understanding this "social structure" of tumors is critical for treatment decisions ...

Radiology & Imaging

Intestinal ultrasound informs management of IBD

(HealthDay)—Point-of-care (POC) intestinal ultrasound (IUS) affects clinical decision-making in inflammatory bowel disease (IBD) and could reduce the need for endoscopy or magnetic resonance imaging (MRI), according to ...

Diseases, Conditions, Syndromes

End-stage kidney disease and the power of decision-making

Older adults with end-stage kidney disease (ESKD) and their caregivers can soon make more informed decisions about treatment options consistent with their values, and better communicate their choices to their families and ...

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