Oncology & Cancer

Searching for the 'signature' causes of BRCAness in breast cancer

Breast cancer cells with defects in the DNA damage repair-genes BRCA1 and BRCA2 have a mutational signature (a pattern of base swaps—e.g., Ts for Gs, Cs for As—throughout a genome) known in cancer genomics as "Signature ...

Medical research

ALS patients differ on treatment choices in later phases of disease

Two new studies analyzing treatment decisions in late-stage amyotrophic lateral sclerosis (ALS) patients shed light onto treatments aimed to extend the duration and quality of life in this progressively debilitating neuromuscular ...

Oncology & Cancer

Minimal residual disease alone not predictive in T-cell leukemia

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. This disease includes two subtypes, B-cell and T-cell leukemia, depending upon the type of white blood cell where the leukemia originates. For B-cell ...

Oncology & Cancer

Cellular origin of a rare form of breast cancer identified

Identifying the cellular origins of breast cancer might lead to earlier diagnosis and more efficient management of the disease. New research led by Charlotte Kuperwasser of Tufts University School of Medicine (TUSM) has determined ...

Oncology & Cancer

New tools improve care for cancers that spread to the brain

Ambitious efforts at UVA Cancer Center to improve care delivered to patients with cancer that has spread to the brain have yielded important insights and tools that can benefit other hospitals, a new publication reports.

Health

Antibiotic residues in water a threat to human health

Antibiotic residues in wastewater and wastewater treatment plants in the regions around China and India risk contributing to antibiotic resistance, and the drinking water may pose a threat to human health, according to a ...

Diseases, Conditions, Syndromes

Malaria testing yet to reach its potential

In a study published this month in Malaria Journal, researchers from Uppsala University and other institutions present a new model for systematically evaluating new malaria treatment programs in routine conditions across ...

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