Introducing bacteria to a tumor's microenvironment creates a state of acute inflammation that triggers the immune system's primary responder cells to attack rather than protect a tumor, according to a new study from the Garvan ...
Mar 13, 2023
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There are substantial state variations in racial and ethnic disparities in triple-negative breast cancer (TNBC) incidence in the United States, according to a study published online March 2 in JAMA Oncology.
Mar 8, 2023
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A new study published in the journal Cell Death & Disease by researchers at the University of Alabama at Birmingham has identified a potential therapeutic target for triple-negative breast cancer, or TNBC, an aggressive treatment-resistant ...
Feb 21, 2023
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Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with this subtype typically have poorer outcomes compared to other breast cancers, suggesting the need for improved treatments. ...
Feb 9, 2023
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Results from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free survival (PFS) times in patients with triple-negative breast cancer (TNBC) that has a "BRCA-like" ...
Jan 31, 2023
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Targeting cellular post-transcription mechanisms in the CD73 ectoenzyme may promote anti-tumor immunity and slow cancer progression in triple-negative breast cancer, according to a Northwestern Medicine study published in ...
Jan 19, 2023
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CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the ...
Jan 11, 2023
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Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells ...
Jan 5, 2023
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Many solid tumors resist treatment in part by turning human biology against itself. Tumors surround themselves with extra white blood cells known as regulatory T cells, which call off the body's natural defenses against the ...
Jan 5, 2023
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Less than 20% of diagnosed breast cancers are designated "triple-negative," lacking three types of receptors often found in other breast cancer types. But TNBCs have a higher risk of recurrence, metastasis and mortality. ...
Nov 30, 2022
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