Medications

Oral deucravacitinib benefits patients with lupus

Tyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phase 2 clinical trial published in Arthritis & Rheumatology has ...

Diseases, Conditions, Syndromes

Mysterious outbreak of bone-eating TB resembles an ancestral form

Tuberculosis is usually encountered as a disease of the lungs, but in 2% of cases in the U.S. it can also be found in the bones. The 9,000-year-old skeletons of some Egyptian mummies show signs of having tuberculosis infection ...

Diseases, Conditions, Syndromes

Oxygen responses of T cells alter protection against tuberculosis

In a new publication in Nature Communications, Martin Rottenberg and Ruining Liu, professor and Ph.D. student at the Department of Microbiology, Tumor and Cell Biology, explain how T cell protection against tuberculosis is ...

Genetics

New antibiotic resistance genes identified in tuberculosis

A massive analysis of more than 10,000 different Mycobacterium tuberculosis bacteria isolates from 23 countries has revealed new genes associated with resistance to 13 first- and second-line new and repurposed antibiotics. ...

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