Neuroscience

New drug pathway linked with tuberous sclerosis

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism. While medications ...

Genetics

Two independent mechanisms are involved in tuberous sclerosis

The current idea about how tuberous sclerosis occurs places mTORC1, a protein complex that regulates cell metabolism, as the major driving force behind the disease. But according to a new study published in the Proceedings ...

Neuroscience

Doctors use robotic assistant to detect source of girl's seizures

Gracin Hahne was 3½ months old when she had her first seizure. "I was changing her diaper," said Heidi Hahne, Gracin's mom. "I also noticed something else: There were light patches, like abnormal pigmentations, on her skin."

Diseases, Conditions, Syndromes

Drug to treat skin lesions in rare tuberous sclerosis complex approved

Scientists at Osaka University developed a new drug treating skin lesions in tuberous sclerosis complex (TSC), a rare intractable disease, a world first. Following the physician-led clinical studies I and II by Osaka University, ...

Neuroscience

Lack of CLOCK protein appears key in severe epilepsy forms

A new study in Neuron focuses on the role that a lack of the protein "CLOCK" plays in several forms of epilepsy. The study provides evidence that excessive excitation of specific brain cells may be due to a lack of CLOCK ...

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