The Organoid group at the Hubrecht Institute produced the first organoid model of the human conjunctiva. These organoids mimic the function of the actual human conjunctiva, a tissue involved in tear production. Using their ...
Jan 11, 2024
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Since their discovery over 100 years ago, neurons called tufted cells, in the brain's olfactory bulb, have been difficult to study. The close proximity between tufted cells and other neurons called mitral cells has restricted ...
Sep 29, 2022
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Researchers at Baylor College of Medicine have uncovered a more detailed picture of how the intestinal epithelium—the lining of the intestines—heals itself after infection with rotavirus. A meticulous single-cell analytical ...
Nov 3, 2021
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Persistent inflammation of the pancreas (chronic pancreatitis) is a known risk factor for developing pancreatic cancer, the third-deadliest cancer in the United States. Tuft cells—cells sensitive to chemical (chemosensory) ...
Apr 18, 2020
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UC San Francisco researchers were recently surprised to discover fully formed gut and skin cells in the thymus, a lemon-sized organ that sits in front of the heart and is responsible for training the T cells of the immune ...
Jul 18, 2018
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Norovirus—the highly contagious gastrointestinal illness best known for spreading rapidly on cruise chips, in nursing homes, schools and other densely populated spaces—kills an estimated 200,000 people annually, mostly ...
Apr 12, 2018
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The lining or epithelium of the gut is one of the body's most diverse and dynamic tissues, an ecosystem of cells that acts as one of the body's main interfaces with the outside world. To better understand this complex tissues ...
Nov 8, 2017
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Cold Spring Harbor Laboratory (CSHL) Professor Christopher Vakoc's team discovered in 2018 a new type of small-cell lung cancer. The cancer originates from cells known as tuft cells. The prognosis for tuft cell lung cancer ...
Jun 22, 2022
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A clinical research team at Tufts Medical Center and Tufts University today published the results of the first randomized placebo-controlled clinical trial of the effectiveness of niclosamide, an oral medication long-used ...
Feb 9, 2022
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Researchers at Vanderbilt University have, for the first time, been able to trigger the specific immune system response required to reverse the course of small intestinal inflammation by inducing production of tuft cells, ...
Aug 31, 2020
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