Oncology & Cancer

Re-exposing a cancer protein to enhance immunotherapy

Successful immunotherapy for cancer involves activating a person's own T cells to identify telltale proteins called antigens on the surface of a tumor and attack it. But some tumors have a trick: They hide themselves from ...

Oncology & Cancer

'Virtual biopsy' uses AI to help doctors assess lung cancer

Imperial researchers have used artificial intelligence (AI) to extract information about the chemical makeup of lung tumors from medical scans. For the first time, they have demonstrated how combining medical imaging with ...

Oncology & Cancer

What reactivates dormant cancer cells?

Researchers at Columbia University have found a molecule that is responsible for arousing dormant cells from breast cancer and nudging them to create metastases. Silencing this molecule, called Malat1, in mice with breast ...

Oncology & Cancer

Liver metastasis, metabolism, and a therapeutic conundrum

A new study led by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) has identified a crucial factor that can drive tumor cells to spread to the liver. The work, which is published in the current issue ...

Oncology & Cancer

Hitchhiking cancer vaccine makes progress in the clinic

Therapeutic cancer vaccines are an appealing strategy for treating malignancies. In theory, when a patient is injected with peptide antigens—protein fragments from mutant proteins only expressed by tumor cells—T cells ...

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