Knocking out part of the innate immune system to improve cancer therapy
Researchers at Shanghai Jiao Tong University School of Medicine, China, have discovered that shutting down part of the innate immune system increases anti-tumor activity.
Researchers at Shanghai Jiao Tong University School of Medicine, China, have discovered that shutting down part of the innate immune system increases anti-tumor activity.
When Nancy Klauber-DeMore, M.D., began studying secreted frizzled-related protein 2, or SFRP2, it was as a breast cancer researcher and surgeon. Since she first showed in 2008 that the protein is involved in tumor growth ...
Dec 5, 2023
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Researchers at the University of Tsukuba have demonstrated that in T follicular helper cell lymphoma, a subgroup of hematologic malignancies, individual tumor cells are highly heterogeneous, even within the same patient.
Dec 5, 2023
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In clinical practice, drug resistance poses a significant challenge in cancer treatment. The process of developing resistance is regulated by complex decision-making pathways and genetic signal networks. The cross-redundancy ...
Dec 5, 2023
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A new study from Karolinska Institutet, published in Cell Reports, shows that tumor-associated macrophages, which are white blood cells that are found in breast tumors, can both help and hinder the spread of cancer cells ...
Dec 4, 2023
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As one of the most insidious diseases in the world, cancer has few treatments that work to eradicate it completely. Now, a new approach pioneered by two researchers working at the University of Missouri's Roy Blunt NextGen ...
Dec 4, 2023
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A study by the University of the Basque Country (UPV/EHU) uses game theory to establish that tumors with less cellular heterogeneity are more aggressive
Dec 4, 2023
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Chimeric antigen receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-treat cancers, as they have the ability to deliver targeted therapies that can kill tumor cells.
Dec 1, 2023
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Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for pediatric patients with relapsed and recurrent leukemia. However, these therapies are not as effective in treating ...
Nov 30, 2023
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Combining a pair of experimental drugs may help treat malignant peripheral nerve sheath tumors with fewer harmful side effects, according to preliminary animal studies led by investigators at the Johns Hopkins Kimmel Cancer ...
Nov 30, 2023
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