Catherine Wu has been a pioneer in a promising approach to fight cancer: vaccines that target specific immune-stimulating molecules, known as immunogenic peptides, generated by the distinct genetic mutations of any individual ...
Apr 16, 2024
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A study has revealed how aberrant epigenetic regulation contributes to the development of atypical teratoid/rhabdoid (AT/RT) tumors, which are aggressive brain tumors that mainly affect young children. There is an urgent ...
Apr 15, 2024
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Scientists have unraveled the mechanisms of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) signaling pathway activated by micronuclei, as well as its significant ...
Apr 9, 2024
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Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia. New findings indicate that periostin, or POSTN, promotes ESCC progression by enhancing cancer and stromal cell ...
Apr 9, 2024
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A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of ...
Apr 9, 2024
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SYNC-T, an investigational therapy that combines a device-induced vaccination at the tumor site with intratumoral infusion of a multitarget biologic drug led to numerous clinical responses in patients with metastatic castrate-resistant ...
Apr 8, 2024
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Researchers from The University of Texas MD Anderson Cancer Center presented encouraging findings from two clinical trials in a plenary session highlighting advances in novel immunotherapy approaches at the American Association ...
Apr 8, 2024
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Hypoxia-activated prodrugs (HAPs) have the potential to activate specifically in hypoxic tumors and eliminate tumor cells, which has brought new opportunities for safe and effective anticancer therapy. However, their therapeutic ...
Apr 3, 2024
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In a new study published in Molecular Oncology, researchers have discovered a novel mechanism to enhance the body's immune response to tumors.
Apr 3, 2024
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A recent study has discovered the function of mechanical constraints in glioblastoma. This study led by Prof. Chen from the Department of Biomedical Engineering at New York University explored the underlying mechanotransductive ...
Apr 2, 2024
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