Uncovering the network of genes regulated by a crucial molecule involved in cancer called mTOR, which controls protein production inside cells, researchers at the University of California, San Francisco (UCSF) have discovered ...
Feb 22, 2012
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(Medical Xpress) -- Mutations to a gene called p53 have been linked to half of all cancers, leading to tumor growth and the spread of cancerous cells. Now, a Cornell-led study identifies for the first time the mechanisms ...
Aug 24, 2011
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Research from the University of Louisville published today (June 6) in the Proceedings of the National Academy of Sciences indicates the removal of a tiny RNA molecule in mice suppresses carcinogenic tumor formation. The ...
Jun 6, 2011
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The proteins that provide cells with a sense of personal space could lead to a therapeutic target for Neurofibromatosis Type 2 (NF2), an inherited cancer disorder, according to researchers at The Wistar Institute. Their findings, ...
Apr 15, 2011
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Genetic confirmation of the suspected diagnosis of "hereditary colorectal cancer" is of great importance for the medical care of affected families. However, many of the variants identified in the known genes cannot currently ...
Dec 7, 2023
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To form a cancer, cells need to accumulate oncogenic mutations that confer tumor-initiating properties. However, recent evidence has shown that oncogenic mutations occur at a surprisingly high frequency in normal tissues, ...
Nov 15, 2023
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An investigational therapy for solid tumors could be especially effective when combined with immunotherapy to target a specific kind of cancer cell, a research team at Duke and Harvard have found.
Nov 8, 2023
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Cisplatin is a potent chemotherapeutic agent used to treat various cancers, including cervical cancer. But the continued use of cisplatin can lead to the development of cisplatin resistance and other side effects, like chemotherapy-induced ...
Jul 20, 2023
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In a paper published in NAR Cancer, researchers from the Center for Childhood Cancer Research at Nationwide Children's and their collaborators report a comprehensive 3D chromatin structural analysis and characterization of ...
Jun 14, 2023
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p53 is one of the most important proteins in cancer biology. Often referred to as a "guardian of the genome," p53 becomes activated in response to various cellular stressors like DNA damage. Its activation induces different ...
Jul 12, 2022
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