Oncology & Cancer

Metastatic cancer gorges on fructose in the liver

Biomedical engineers at Duke University have demonstrated that metastatic cancer cells can reprogram their metabolism to thrive in new organs. Specifically, the research shows that cells originating from colorectal cancer ...

Oncology & Cancer

Researchers find a way to 'starve' cancer

Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital ...

Immunology

Energizing the immune system to eat cancer

Immune cells called macrophages are supposed to serve and protect, but cancer has found ways to put them to sleep. Now researchers at the Abramson Cancer Center of the University of Pennsylvania say they've identified how ...

Oncology & Cancer

Lung cancer resistance: the key is glucose

Cancers are not only made of tumor cells. In fact, as they grow, they develop an entire cellular ecosystem within and around them. This "tumor microenvironment" is made up of multiple cell types, including cells of the immune ...

Oncology & Cancer

Fundamental cancer metabolism dogma revisited

A new paper in Nature Communications reveals new insights into adaptations made by cancer cells to rewire their metabolism to achieve growth and survive. Among the discoveries include a challenge to a well-known feature in ...

Oncology & Cancer

Study challenges long-standing concept in cancer metabolism

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that lactate provides a fuel for growing tumors, challenging a nearly century-old observation known as the Warburg effect.

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