A research team with the Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Sciences reported their discovery that a metabolic regulation mechanism may play a role in malignant transformation of non-alcoholic ...
Nov 29, 2021
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Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key ...
Aug 16, 2022
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PGK1, a glycolytic enzyme, has been found to play a role in coordinating cellular processes crucial to cancer metabolism and brain tumor formation, according to results published in today's online issue of Molecular Cell. ...
Mar 3, 2016
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An enzyme that blocks the metabolic processes that contribute to the rapid growth and spread of liver cancer has been discovered, according to a study by researchers at Sanford Burnham Prebys and Weill Cornell Medicine. The ...
Jun 26, 2020
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An international team of researchers has found a possible way to reenergize T cells exhausted from fighting a cancerous tumor. In their paper published in the journal Science Immunology, the group describes their study of ...
According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks ...
Aug 25, 2021
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Progress against DIPG, a fatal childhood brain tumor, is usually a game of inches. Studies that hint at even small gains are cause for celebration.
Aug 13, 2020
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Abnormal metabolism within the cells is a distinctive characteristic of cancer, but until now, the mechanism that causes cells to undergo this metabolic shift remained unknown.
Feb 11, 2015
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A study of the lead agent CPI-613 in a class of anti-cancer drugs undergoing Food and Drug Administration (FDA) approved clinical trials reveals that CPI-613 is effective against most carcinoma cell lines, and used in combination, ...
Jun 9, 2022
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A metabolic pathway that is up-regulated in certain breast cancers promotes the disease's progression by activating a cell signaling protein called Arf6, according to a paper published in the Journal of Cell Biology. The ...
Apr 6, 2016
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