Oncology & Cancer

Improving cancer immunotherapy by prolonging T-cell survival

In the past decade, immunotherapy has emerged as the fourth pillar of cancer treatment, joining surgery, radiotherapy and chemotherapy. It is an approved treatment for 15 cancers, including melanoma and some types of lymphomas ...

Oncology & Cancer

Novel mechanism supports antitumor response and T-cell survival

A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of ...

Medical research

Enhancing hypoxia-activated prodrug anticancer therapy

Hypoxia-activated prodrugs (HAPs) have the potential to activate specifically in hypoxic tumors and eliminate tumor cells, which has brought new opportunities for safe and effective anticancer therapy. However, their therapeutic ...

Oncology & Cancer

Investigating mechanisms of aggressive glioblastoma tumor growth

Northwestern Medicine investigators have identified a metabolism-related gene that may play a role in recruiting immune cells to support the growth of aggressive brain tumors, according to a study recently published in Nature ...

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