Malaria and typhoid fever are major health problems in tropical regions, but accurate diagnosis is often hampered by overlapping or nonspecific symptoms and limited access to diagnostics. Now, NIBIB-funded scientists have ...
Mar 11, 2022
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A new study has uncovered key details for how the Salmonella bacteria that causes typhoid fever identifies a host's immune cells and delivers toxins that disrupt the immune system and allow the pathogen to spread.
Feb 25, 2020
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Scientists have revealed how the typhoid toxin works to hijack DNA repair machines and accelerate the aging of cells, a breakthrough that could pave the way for new strategies to combat the killer disease.
Sep 6, 2019
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That statin you've been taking to lower your risk of heart attack or stroke may one day pull double duty, providing protection against a whole host of infectious diseases, including typhoid fever, chlamydia, and malaria.
Aug 21, 2017
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The team has completed two genomics studies on the tropical disease, a condition that is estimated to cause up to 30 million illnesses and over a quarter of a million deaths globally each year.
May 26, 2015
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There is an urgent need to develop global surveillance against the threat to public health caused by antimicrobial resistant pathogens, which can cause serious and untreatable infections in humans. Typhoid is a key example ...
May 11, 2015
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The bacterium Salmonella Typhi causes typhoid fever in humans, but leaves other mammals unaffected. Researchers at University of California, San Diego and Yale University Schools of Medicine now offer one explanation—CMAH, ...
Dec 4, 2014
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Scientists said Monday they had found a variant of a gene that confers a near five-fold protection against typhoid fever, which kills millions of people each year.
Nov 10, 2014
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Typhoid fever is one of the oldest documented diseases known to have afflicted mankind but what makes it so lethal has remained a mystery for centuries. In a study appearing online July 10 in the journal Nature, Yale researchers ...
Jul 10, 2013
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(Medical Xpress)—Vaccines that employ weakened but live pathogens to trigger immune responses have inherent safety issues but Yale researchers have developed a new trick to circumvent the problem—using bacteria's own ...
Mar 13, 2013
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