Diseases, Conditions, Syndromes

Why cholera continues to threaten many African countries

Malawi is facing its worst cholera outbreak in two decades. The outbreak started early in 2022 and has, so far, resulted in over 18,000 cases and the loss of 750 lives. It's also forced the closure of schools and many businesses. ...

Diseases, Conditions, Syndromes

For struggling Haiti, return of cholera is a 'catastrophe'

When humanitarian officials in Haiti try to describe their concerns over a new, fast-spreading cholera epidemic, they struggle to find words strong enough: "alarming," "chaotic," even "a catastrophe."

Gastroenterology

War in the gut: How human microbiota resist the cholera bacterium

Cholera is still an enormous public health problem. There have been seven major pandemics of the acute diarrheal disease in the last 200 years. According to the WHO, cholera still kills up to 143,000 people each year and ...

Medical research

Antibiotic tolerance study paves way for new treatments

A new study identifies a mechanism that makes bacteria tolerant to penicillin and related antibiotics, findings that could lead to new therapies that boost the effectiveness of these treatments.

Diseases, Conditions, Syndromes

Potential cholera vaccine target discovered

Findings from a team led by investigators at Massachusetts General Hospital (MGH), reported in the online journal mBio, may help scientists develop a more effective vaccine for cholera, a bacterial disease that causes severe ...

Diseases, Conditions, Syndromes

Cause of 1990s Argentina cholera epidemic uncovered

The evolution of epidemic and endemic strains of the cholera-causing bacterium Vibrio cholerae in Argentina has been mapped in detail by researchers at the Wellcome Sanger Institute, the London School of Hygiene and Tropical ...

Diseases, Conditions, Syndromes

Vaccine study confirms sensitivity of cholera test

Recently, the sensitivity of fecal microbiological cultures for detecting cholera has come under question. Researchers reporting in PLOS Neglected Tropical Diseases investigated this claim using a 'vaccine probe' analysis ...

Diseases, Conditions, Syndromes

How cholera bacteria make people so sick

The enormous adaptability of the cholera bacterium explains why it is able to claim so many victims. Professor Ariane Briegel from the Leiden Institute of Biology has now discovered that this adaptability is due to rapid ...

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