Immunology

A novel mechanism that triggers a cellular immune response

Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases, the predominant response involves antibodies, proteins made by the immune system that ...

Medical research

Disease severity linked to N protein of SARS-CoV-2

A multicenter collaboration tracking the spread and evolution of the SARS-CoV-2 virus in Saudi Arabia has identified mutations in the virus's N protein associated with increased viral loads in COVID-19 patients. The study ...

Diseases, Conditions, Syndromes

Tracking a moving target

The influenza pandemic that began in Mexico in April 2009 rapidly spread throughout the world and arrived in Japan one month later. Now, a research team led by Toshihisa Ishikawa at the RIKEN Omics Science Center in Yokohama ...

Diseases, Conditions, Syndromes

Researchers make progress toward Epstein-Barr virus vaccine

A research team led by scientists from NIH's National Institute of Allergy and Infectious Diseases (NIAID) has determined how several antibodies induced by Epstein-Barr virus (EBV), a herpesvirus that causes infectious mononucleosis ...

Diseases, Conditions, Syndromes

New insights into herpes virus could inform vaccine development

A team of scientists has discovered new insights into the mechanisms of Epstein-Barr virus (EBV) infection, as well as two antibodies that block the virus' entry into cells. The findings, published in Proceedings of the National ...

Diseases, Conditions, Syndromes

Why RNA vaccines for COVID-19 raced to the front of the pack

Developing and testing a new vaccine typically takes at least 12 to 18 months. However, just over 10 months after the genetic sequence of the SARS-CoV-2 virus was published, two pharmaceutical companies applied for FDA emergency ...

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