Medical research

Cellular calpain proteases can cleave the enteroviral polyprotein

Enteroviruses are small, non-enveloped RNA viruses, which belong to the family of picornaviruses. Although most of the diseases that enteroviruses cause are symptomless or mild, enteroviruses are the most common viruses infecting ...

Diseases, Conditions, Syndromes

Scientists crack rabies virus weaponry

Researchers have found a way to stop the rabies virus shutting down the body's immune defence against it. In doing so they have solved a key scientific puzzle and have laid the foundation for the development of new anti-rabies ...

Medical research

Researchers describe building blocks of HIV's protective shell

The genome of the HIV-1 virus is protected by a conical-shaped protein shell called a capsid, which performs many functions crucial to viral infection—shielding the virus from the immune system, attaching to cell's transport ...

Medical research

Molecular switch for 'exhaustion mode' of immune cells discovered

Tumors and certain viral infections pose a challenge to the human body which the immune system typically fails to handle. In these diseases it switches to a hypofunctional state that prevents adequate protection. However, ...

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