Diseases, Conditions, Syndromes

Combination therapy treats leishmaniasis, HIV patients

Coinfection with visceral leishmaniasis (VL) and human immunodeficiency virus (HIV) has been observed in at least 35 countries on four continents and requires special case management. Currently, the World Health Organization ...

Diseases, Conditions, Syndromes

Genes key to identifying drug resistant parasites in Brazil

Researchers at the University of York have identified genes in a parasite that could help clinicians predict drug treatment outcomes for patients with visceral leishmaniasis in Brazil.

Immunology

How chronic infections can outsmart the immune system

Professor Simona Stäger and her team at INRS have discovered a mechanism that causes the body to sabotage its own defenses against infection by visceral leishmaniasis, a fatal tropical disease. This discovery could help ...

Diseases, Conditions, Syndromes

Discovery of a new potential treatment for visceral leishmaniasis

A new preclinical candidate drug with the potential to treat visceral leishmaniasis, one of the world's major neglected diseases, has been discovered through a close collaboration between the University of Dundee, GSK and ...

Diseases, Conditions, Syndromes

New information on a major player in chronic visceral leishmaniasis

In an article in the latest issue of PLOS Pathogens, INRS professor Simona Stäger and her team show how the parasite Leishmania donovani uses a physiological response to low oxygen levels (hypoxia) to establish a chronic ...

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