Immunology

Innate immune responses to high-fat diets lead to obesity

Why is eating a high fat diet a recipe for obesity? According to a new study from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan, the answer involves the activity of a specific type of immune cell that lives ...

Medical research

Cholesterol-lowering drugs reduce brown adipose tissue

ETH Zurich scientists have shown that statins, one of the most commonly prescribed classes of pharmaceuticals, reduce beneficial brown adipose tissue. But this is no reason to demonise these drugs, the researchers insist.

Medical research

Novel immune cells control neurons responsible for fat breakdown

The biological causes underlying obesity have been under intense scrutiny, with studies suggesting a link between the nervous and the immune systems. Now, in a breakthrough study to be published in Nature Medicine on 9 October, ...

Medical research

Heart hormones protect against obesity and insulin resistance

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) in Lake Nona, Florida have shown that enhanced natriuretic peptide (NP) signaling in adipose tissue protects against obesity and insulin resistance. ...

Medical research

Revealed: Brain 'switch' tells body to burn fat after a meal

Scientists at Monash University's Biomedicine Discovery Institute have found a mechanism by which the brain coordinates feeding with energy expenditure, solving a puzzle that has previously eluded researchers and offering ...

Medical research

Molecular pilot light prepares body's heating system for the cold

As we bask in the summer heat, it is easy to take for granted that humans are also prepared for the cold of winter, with overcoats in the closet and home heating systems ready to be fired up as an added assurance against ...

Medical research

Mice will help reveal the roles of human brown fat

When it gets cold around you, your body turns up the heat to maintain its normal temperature. The heat is produced by brown adipose tissue, or brown fat, which also plays a role in how the body uses glucose and fat. However, ...

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