Deleting the TSC2 gene in specific lung cells of mice led to the activation of the mTORC1 signaling pathway and pulmonary disease characteristics consistent with human LAM disease, particularly in female breeder mice. These ...
Nov 9, 2020
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221
A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.
Sep 15, 2020
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85
Brain cancer in children is always a devastating diagnosis, but McMaster University researchers may have found a way to have the most serious types of pediatric brain cancer respond better to therapies.
Aug 28, 2020
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509
Why do humans have hair on our arms and legs but not on the palms of our hands and the soles of our feet? It's a fundamental question in human evolution that researchers at the Perelman School of Medicine at the University ...
Nov 28, 2018
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294
Scientists at the Oklahoma Medical Research Foundation have broken new ground in understanding how the lymphatic system works, potentially opening the door for future therapies.
Oct 16, 2018
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Researchers from the University of Dundee and the Francis Crick Institute have made a significant discovery about a cellular pathway associated with developmental defects and a myriad of diseases ranging from alopecia to ...
Mar 22, 2018
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1
Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich (TUM) has now discovered that microRNA 29 (miR-29) ...
Nov 22, 2017
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0
Researchers at the Francis Crick Institute have discovered a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies.
Oct 17, 2017
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159
Researchers at McMaster University have learned more about the regulation of a cellular signalling pathway involved in the development of several types of cancer, including colon cancer.
Sep 12, 2017
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9
Neuroblastoma is a cancer in children that originates in the sympathetic nervous system and has a high mortality. Current treatment includes chemotherapy and radiotherapy with their potentially severe side effects; there ...
Jul 27, 2017
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