A research team with members from Monash University, the ARC Centre for Cryo-electron Microscopy of Membrane Proteins, the University of Tokyo and the University of Otago have determined the shape and kinetics of an important cell surface (membrane) receptor called calcitonin gene-related peptide (CGRP), which has long been implicated in migraine. The work has been published in the journal Science.

In a new paper published by Nature Communications, The Lundquist Institute (TLI) Investigator Wei Yan, MD, Ph.D., and his research colleagues spell out an innovative strategy that has led to the discovery of a natural compound as a safe, effective and reversible male contraceptive agent in pre-clinical animal models. Despite tremendous efforts over the past decades, the progress in developing non-hormonal male contraceptives has been very limited.

A new study led by Belgian and Spanish researchers published in Scientific Reports adds evidence about the potential benefits of green tea extracts in Down syndrome. The researchers observed that the intake of green tea extracts can reduce facial dysmorphology in children with Down syndrome when taken during the first three years of life. Additional experimental research in mice confirmed the positive effects at low doses. However, they also found that high doses of the extract can disrupt facial and bone development. More research is needed to fully understand the effects of green tea extracts and therefore they should always be taken under medical supervision.

Our brains are non-stop consumers. A labyrinth of blood vessels, stacked end-to-end comparable in length to the distance from San Diego to Berkeley, ensures a continuous flow of oxygen and sugar to keep our brains functioning at peak levels.

One of the most significant genetic risk factors for developing Alzheimer's disease is a gene called APOE4, which is carried by almost half of all Alzheimer's patients. A new study from MIT shows that this gene has widespread effects on brain cells' ability to metabolize lipids and respond to stress.