Best of week 17 / 2022

Study of 2,000 patients after hospitalization with COVID-19 shows only around 1 in 4 feel fully recovered after 1 year

A new UK study of more than 2,000 patients after hospitalization with COVID-19 presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon 23-26), and published in The Lancet Respiratory Medicine shows that, one year after having COVID-19, only around one in four patients feel fully well again. The study is led by Professor Christopher Brightling, Dr. Rachael Evans, and Professor Louise Wain, National Institute for Health Research Leicester Biomedical Research Center, University of Leicester, UK and colleagues.

Pfizer COVID-19 third dose vaccine protection against hospitalization from omicron wanes after 3 months: study

A study released April 22 in The Lancet Respiratory Medicine shows that a booster dose of the Pfizer COVID-19 vaccine provides strong protection, roughly 80% to 90%, in the first few months against hospital admissions and emergency department visits caused by the delta and omicron variants. However, against omicron, this protection wanes over time—even after a third dose.

Tumors partially destroyed with sound don't come back

Noninvasive sound technology developed at the University of Michigan breaks down liver tumors in rats, kills cancer cells and spurs the immune system to prevent further spread—an advance that could lead to improved cancer outcomes in humans.

Some cases of long COVID-19 may be caused by an abnormally suppressed immune system

A UCLA-led team of researchers studying the effect of the monoclonal antibody Leronlimab on long COVID-19 may have found a surprising clue to the baffling syndrome, one that contradicts their initial hypothesis. An abnormally suppressed immune system may be to blame, not a persistently hyperactive one as they had suspected.

Antidepressants are not associated with improved quality of life in the long run

Over time, using antidepressants is not associated with significantly better health-related quality of life, compared to people with depression who do not take the drugs. These are the findings of a new study published this week in the open-access journal PLOS ONE by Omar Almohammed of King Saud University, Saudi Arabia, and colleagues.

Multiple treatments to slow age-related muscle wasting

Everyone wants to stay fit and healthy as they grow old. But as we age, our body degrades, our muscles shrink and strength declines. Some older people suffer from excessive muscle loss, a condition known as sarcopenia. University of Basel researchers show that a combination therapy could delay the onset of sarcopenia.

Scientists uncover key cellular mechanism that shows saturated fat can worsen diabetes

Scientists at Nanyang Technological University, Singapore's (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine) have mapped a novel cellular pathway that shows that saturated fat contributes to the development of diabetes and can worsen the disease, underscoring its role in metabolic diseases.

Some autism spectrum disorder symptoms linked to astrocytes

Abnormalities in a type of brain cell called astrocytes may play a pivotal role in causing some behavioral symptoms of autism spectrum disorders, according to a preclinical study by Weill Cornell Medicine investigators.

Researchers find genetic 'Achilles heel' in ovarian and uterine cancers

Although the outlook for people with some types of cancers has improved in the past 20 years, outcomes for patients with uterine and ovarian cancers remain much the same. Patients often have advanced disease before they are diagnosed, and genes that drive tumor formation have proved difficult to target with new treatments.

Coronavirus found in human feces up to 7 months after infection

COVID-19 is mainly known as a respiratory ailment, but a new study suggests the coronavirus can infect your intestinal tract for weeks and months after you've cleared the bug from your lungs.