Best of week 28 / 2022

Only seven percent of adults have good cardiometabolic health

Less than 7 percent of the U.S. adult population has good cardiometabolic health, a devastating health crisis requiring urgent action, according to research led by a team from the Friedman School of Nutrition Science and Policy at Tufts University in a pioneering perspective on cardiometabolic health trends and disparities published in the July 12 issue of the Journal of the American College of Cardiology. Their team also included researchers from Tufts Medical Center.

Uncovering one of the driving forces of Alzheimer's disease

Alzheimer's disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.

Researchers discover non-invasive stimulation of eye as potential treatment of depression and dementia

A joint research team from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and City University of Hong Kong (CityU) has discovered that the electrical stimulation of the eye surface can alleviate depression-like symptoms and improve cognitive function in animal models. These significant findings were recently published in Brain Stimulation and the Annals of the New York Academy of Sciences.

Improving research on diet and dementia

Anyone searching the internet for brain healthy foods will find no shortage of stories making dietary recommendations. Some of those stories point to observational studies that have suggested a link between the lower or greater intake of certain foods and the risk of dementia. But clinical research attempting to connect specific nutrients or diets to cognitive function have not found convincing evidence.

Long term high-fat diet expands waistline and shrinks brain

New research shows that fatty foods may not only be adding to your waistline but also playing havoc with your brain.

A rhythmic small intestinal microbiome prevents obesity and type 2 diabetes

An estimated 500 to 1,000 bacterial species reside in each person's gut, perhaps numbering 100,000 trillion microorganisms. In a new paper, published July 5, 2022 in Cell Reports, researchers at University of California San Diego School of Medicine used mouse models to explore how diet and feeding patterns affect these intestinal microbes—and the health of the hosts, particularly with obesity and type 2 diabetes.

Molecule boosts fat burning

Normally, fat cells store energy. In brown fat cells, however, energy is dissipated as heat—brown fat thus serves as a biological heater. Most mammals therefore have this mechanism. In humans it keeps newborns warm; in human adults, brown fat activation positively correlates with cardio-metabolic health.

Mindfulness meditation reduces pain by separating it from the self

For centuries, people have been using mindfulness meditation to try to relieve their pain, but neuroscientists have only recently been able to test if and how this actually works. In the latest of these efforts, researchers at University of California San Diego School of Medicine measured the effects of mindfulness on pain perception and brain activity.

Universal influenza B vaccine induces broad, sustained protection, researchers find

A new universal flu vaccine protects against influenza B viruses, offering broad defense against different strains and improved immune protection, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State University.

Hereditary factors that increase the likelihood of cancer mutations detailed in new study

Mutations occur in various tissues and organs of an individual. Somatic mutations occur in cells that will not give rise to offspring and are therefore not passed on to subsequent generations. Caused by a large number of factors such as age and smoking, somatic mutations are the main cause of cancer and also play a role in other diseases.