Top news stories of February 18, 2023

Researchers find nanoparticles of a rare earth metal used in MRI contrast agents can infiltrate kidney tissue

Physicians routinely prescribe an infusion containing gadolinium to enhance MRI scans, but there is evidence that nanoparticles of the toxic rare earth metal infiltrate kidney cells, sometimes triggering severe side effects, University of New Mexico researchers have found.

Humans don't hibernate, but we still need more winter sleep

Whether we're night owls or morning larks, our body clocks are set by the sun. Theoretically, changing day length and light exposure over the course of the year could affect the duration and quality of our sleep. But figuring out how this applies in practice is difficult. Although studies where people assess their own sleep have suggested an increase in sleep duration during winter, objective measures are needed to determine how exactly the seasons affect sleep.

Toxic protein linked to muscular dystrophy and arhinia

Researchers at the National Institutes of Health and their colleagues have found that a toxic protein made by the body called DUX4 may be the cause of two very different rare genetic disorders. For patients who have facioscapulohumeral muscular dystrophy (FSHD), or a rare facial malformation called arhinia, this research discovery may eventually lead to therapies that can help people with these rare diseases.

Achieving a better understanding of how the blood-brain barrier works

Up to now, the use of models to research the barrier that separates the circulatory from the nervous system has proven to be either limited or extremely complicated. Researchers at ETH Zurich have developed a more realistic model that can also be used to better explore new treatments for brain tumors.

Space travel influences the way the brain works

Scientists of the University of Antwerp and University of Liège (Belgium) have found how the human brain changes and adapts to weightlessness after being in space for six months. Some of the changes turned out to be lasting—even after eight months back on Earth. Raphaël Liégeois, soon to be the third Belgian in space, acknowledges the importance of the research "to prepare the new generation of astronauts for longer missions."