Top news stories of May 23, 2026

Gut-lung microbe shifts may explain clozapine's severe bowel and lung side effects

Schizophrenia is a severe mental health disorder characterized by hallucinations, false and rigid beliefs (i.e., delusions), impaired mental functions, disorganized speech and, in some cases, repetitive body movements. This debilitating disorder is typically treated with antipsychotics, medications that alter the signaling between neurons.

Brain inflammation is unlikely to explain persistent long COVID symptoms, neuroimaging study finds

A new brain imaging study has found no evidence of widespread brain inflammation in patients suffering from prolonged symptoms after COVID-19 infection. Instead, the most severe long COVID symptoms were associated with increased brain activity in regions involved in mood and emotion. The study is published in the Journal of Neurology.

COVID-19 mRNA vaccine plus immune system enhancer may reduce need for repeated boosters, say researchers

In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, improved the duration of the vaccine's protection in mice. The combo also showed a more pronounced response against omicron viral components than the vaccine alone.

Psilocybin cuts nerve pain for weeks and boosts gabapentin in mice

A single dose of psilocybin, the active compound in magic mushrooms, reduces nerve pain for up to a month and makes a widely used painkiller work more effectively, University of Reading research has found.

Nitric oxide rewires gene expression in the brain, offering new insight into Alzheimer's disease

Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome—the working portion of our DNA that helps make each person unique. Put simply, a single gene can be edited in different ways to produce multiple sets of instructions. This helps explain why humans differ so significantly from fruit flies and mice, despite having a similar number of genes.