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Oncology & Cancer
Antibody halts triple-negative breast cancer in preclinical models
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with ...
7 hours ago
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Cardiology
Planned birth at term reduces pre-eclampsia in those at high risk, clinical trial finds
Planned birth at term reduces the incidence of preeclampsia in women at high risk of the condition, without increasing emergency Cesarean or neonatal unit admission, according to new trial results.
9 hours ago
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Medical research news
New approach makes common breast cancer type responsive to immunotherapy
A study led by researchers at the Hospital del Mar Research Institute advances one of the most significant milestones in breast cancer treatment, making immunotherapy effective against the most common tumor type, estrogen ...
11 hours ago
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Comprehensive map reveals neuronal dendrites in the mouse brain in greater detail
Understanding the shape or morphology of neurons and mapping the tree-like branches via which they receive signals from other cells (i.e., dendrites) is a long-standing objective of neuroscience research. Ultimately, this ...
Autistic children born preterm often show more complex needs—but share similar genetic background
A new study shows that children born preterm who are later diagnosed with autism often present with more extensive support needs and a higher number of co-occurring conditions than autistic children born at full term. Surprisingly, ...
7 hours ago
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A single shot of HPV vaccine may be enough to fight cervical cancer, study finds
A single HPV vaccination appears just as effective as two doses at preventing the viral infection that causes cervical cancer, researchers reported Wednesday.
13 hours ago
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Single enzyme failure found to drive neuron loss in dementia
Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ferroptosis. The study provides ...
15 hours ago
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Modified herpes virus helps destroy glioblastoma in preclinical models
Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and ...
14 hours ago
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New organ-on-a-chip platform allows the testing of cancer vaccine efficacy in aging populations
Dr. Vadim Jucaud's lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune responses, offering a more accurate testing bed for evaluating cancer vaccine performance ...
14 hours ago
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When anger hurts: How feeling wronged can intensify chronic pain
We all know stress can worsen pain, but new research shows that anger and a sense of injustice may be even more powerful triggers.
15 hours ago
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Rapid, low-cost tests can help prevent child deaths from contaminated medicinal syrups
Researchers at the University of Oxford and their collaborators have demonstrated that simple, rapid, and inexpensive tests can detect deadly contaminants in medicinal syrups—contaminants that have tragically led to the ...
14 hours ago
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Breathe in, breathe out: How respiration shapes remembering
First and foremost, we breathe in order to absorb oxygen—but this vital rhythm could also have other functions. Over the past few years, a range of studies have shown that respiration influences neural processes, including ...
15 hours ago
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Skin-to-brain signal explains why warm hugs make us feel so good about ourselves
As winter closes in, you might start to notice your fingers and toes freezing when you go outside, or your face flushing hot when you go into a heated building. In these moments of changing temperature, we become more aware ...
15 hours ago
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Key kidney sensor that helps control fluid balance identified
A new study has identified a critical "pressure sensor" inside the kidney that helps the body control blood pressure and fluid levels. The finding helps explain how the kidneys sense changes in blood volume—something scientists ...
15 hours ago
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Brain enzyme that drives nicotine addiction and smoking dependence identified
Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, scientists have focused ...
18 hours ago
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Bacterial enzyme may cause fatal heart conditions with pneumonia infections
Pneumonia is a disease that burdens the health care system with more than 1.2 million emergency room visits each year and more than 41,000 adult deaths in the United States. Worldwide, more than one million children under ...
16 hours ago
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How the brain prioritizes bodily signals in conscious awareness
A new study shows that visual and tactile impressions that are related to our own body are prioritized for reaching conscious awareness. This helps us understand how we develop the feeling that the body is our own—through ...
16 hours ago
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Protein unties tangled DNA linked to hotspots of cancer mutations
New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in cancer and identified cancer-driving mutations in an underexplored part of the genome.
15 hours ago
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Ancient genetics and modern pollutants could provide a clue to endometriosis risk
A new study suggests that certain genetic differences, passed down from ancient human ancestors, and exposure to common present-day chemicals could explain why some women are more likely to develop endometriosis.
15 hours ago
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Machine learning reveals how disordered protein regions contribute to cancer-causing condensates
Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, "droplets" of concentrated proteins, DNA or RNA.
17 hours ago
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