Lung Cancer

Team compares effectiveness of four PD-L1 tests

In a recent study, a Yale Cancer Center team compared the performance of the four available PD-L1 assay tests. They found that one of the assays failed to reveal comparable levels of PD-L1, a tumor-promoting protein, while ...

Sep 23, 2016
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At bat against rare blood cancers

At 38-years-old, Aaron Feldman was in the best shape of his life. He played first base and pitched in two competitive baseball leagues and hit the gym daily. He attributed the pain in his chest to soreness from grueling workouts. ...

Sep 20, 2016
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Immunotherapy a hot topic in treating cancers

Last Friday was Rebecca Hertzog Burns' birthday. She turned 2. She says that's her age, though she's really 27. After a relapse in her fight with acute myelogenous leukemia, Burns received a stem cell transplant on Sept. ...

Sep 15, 2016
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Protein may be crucial in many lung ailments

The more proteins that prove essential in the pathways of disease, the more targets drug makers and doctors have for intervention. That's why its potentially important that a new study reports a key role for the protein TMEM219 ...

Sep 16, 2016
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Why isn't there a gene for depression?

Depression is sometimes categorised as a mental, rather than a physical illness – as though somehow mental health is different from physical health. But the brain is not a magical black box inside your head. It is an organ, ...

Sep 15, 2016
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Lung cancer is a disease characterized by uncontrolled cell growth in tissues of the lung. If left untreated, this growth can spread beyond the lung in a process called metastasis into nearby tissue and, eventually, into other parts of the body. Most cancers that start in lung, known as primary lung cancers, are carcinomas that derive from epithelial cells. Worldwide, lung cancer is the most common cause of cancer-related death in men and women, and is responsible for 1.3 million deaths annually, as of 2004. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss.

The main types of lung cancer are small-cell lung cancer (SCLC), also called oat cell cancer, and non-small-cell lung cancer (NSCLC). The most common cause of lung cancer is long-term exposure to tobacco smoke. Nonsmokers account for 15% of lung cancer cases, and these cases are often attributed to a combination of genetic factors, radon gas, asbestos, and air pollution including secondhand smoke.

Lung cancer may be seen on chest radiograph and computed tomography (CT scan). The diagnosis is confirmed with a biopsy. This is usually performed by bronchoscopy or CT-guided biopsy. Treatment and prognosis depend on the histological type of cancer, the stage (degree of spread), and the patient's general wellbeing, measured by performance status. Common treatments include surgery, chemotherapy, and radiotherapy. NSCLC is sometimes treated with surgery, whereas SCLC usually responds better to chemotherapy and radiation therapy. This is partly because SCLC often spreads quite early, and these treatments are generally better at getting to cancer cells that have spread to other parts of the body.

Survival depends on stage, overall health, and other factors, but overall 14% of people in the United States diagnosed with lung cancer survive five years after the diagnosis.

This text uses material from Wikipedia licensed under CC BY-SA

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