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Immunology news
Oncology & Cancer
New effective treatment for deadly pancreatic cancer may be on its way
Pancreatic cancer is one of the deadliest of all cancers. Only 12% of men diagnosed with pancreatic cancer are alive five years after diagnosis; for women it is 14%.
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Diseases, Conditions, Syndromes
Longitudinal study reveals HPV infection kinetics
Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a study published January 21 in the open-access journal PLOS Biology by Samuel ...
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New 'Human Microglia Atlas' provides insights into roles of immune cells in neurodegenerative diseases
Inflammation is triggered by the immune system and is part of the body's natural response to injuries or disease. However, abnormal inflammation has recently been established as a hallmark for pathologies that were previously ...
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Researchers find protein that may stop autoimmune diseases and allergies
Houston Methodist researchers have identified a key protein as a potential therapeutic target for stopping the body's immune system from mistakenly attacking itself, offering new hope for treating autoimmune diseases and ...
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Microglia show sex-specific responses, with potentially broad implications in neurological disease research
A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another "crew" of responders is busy clearing debris and repairing injured tissue.
3 hours ago
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Stoking 'good' antibodies could be key to reducing serious bee venom allergic reactions
Monash University scientists have identified an immune system power play behind serious bee venom allergy, which lands twice as many Australians in hospital emergency departments each year as snake or spider bites.
23 hours ago
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New study paves way for immunotherapies tailored for childhood cancers
Researchers at Karolinska Institutet and the Astrid Lindgren Children's Hospital in Sweden have determined how children's immune systems react to different kinds of cancer depending on their age. The study, which is published ...
Jan 20, 2025
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Investigating new treatments for rare skin lymphomas
A fusion protein therapy may be an effective treatment option for cutaneous T-cell lymphomas, according to a multicenter clinical trial published in the Journal of Clinical Oncology.
Jan 20, 2025
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Algorithm to spot cancer warning signs in standard blood tests to be used by EU's NHS
Scientists at the University of Exeter have found a new way of interpreting standard blood tests to help GPs spot cancer warning signs—and the test is now being integrated in an NHS trust.
Jan 20, 2025
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A chain reaction: HIV vaccines can lead to antibodies against antibodies
Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection.
Jan 17, 2025
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Specific neurons with an immune 'doorbell' may influence mood and memory
Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states. In disease, high levels of IL-1 in the brain are linked to neuroinflammation, which can disrupt ...
Jan 17, 2025
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Key enzyme identified as potential target for cancer immunotherapy
Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzyme—P4HA1 prolyl hydroxylase, is strongly induced in CD8+ T cells in solid cancer, the primary immune cells involved in combating ...
Jan 17, 2025
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Researchers discover how cigarette smoke impairs critical lung immune cells
Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory illnesses is incomplete, which has severely hampered the development of effective treatments. Today ...
Jan 17, 2025
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Large-scale analysis discovers genetic loci associated with allergic sensitization
A research team from University of Tsukuba performed a large-scale genome analysis of Japanese and European populations and discovered gene regions (genetic polymorphisms) related to allergic sensitization.
Jan 17, 2025
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Megakaryocytes' immune characteristics and role elucidated
Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts. Recent advances in technology ...
Jan 17, 2025
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Study reveals immune system changes linked to schizophrenia and treatment resistance
Researchers from Singapore's National Healthcare Group (NHG)'s Institute of Mental Health (IMH) and Agency for Science, Technology and Research (A*STAR) have made strides in understanding the connection between the immune ...
Jan 16, 2025
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Eavesdropping on organs: Immune system controls blood sugar levels during periods of low energy
A study published in Science by the Champalimaud Foundation reveals a surprising new role for the immune system. During periods of low energy—such as intermittent fasting or exercise—immune cells step in to regulate blood ...
Jan 16, 2025
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Multi-target approach counters tumor growth in several cancers
The tissue adjacent to a tumor behaves differently than areas farther away. The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven in which the tumor can ...
Jan 16, 2025
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Protein CD74 can predict immunotherapy response in bowel cancer, independent of subtype
Bowel cancer is the fourth most common cancer in the UK, and the second most common cause of cancer death. The disease falls into two types: one where proteins that repair errors in DNA are missing or deficient (the deficient ...
Jan 16, 2025
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Wildfires ignite infection risks by weakening the body's immune defenses and spreading bugs in smoke
Over the past several days, the world has watched on in shock as wildfires have devastated large parts of Los Angeles.
Jan 16, 2025
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Lupus patients may require tailored COVID-19 vaccination strategies
A recent study by Emory University researchers provides new insights into why the mRNA vaccines developed to fight COVID-19 in 2021 are less effective in patients with autoimmune diseases. By providing insights into the cellular ...
Jan 15, 2025
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A 'perfect storm' of mutations: How chronic hepatitis C infection leads to autoimmune disease
Scientists at the Garvan Institute of Medical Research have discovered how a viral infection causes autoimmune disease, disproving a long-standing theory and opening a promising new approach to developing treatments for autoimmune ...
Jan 15, 2025
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Chameleon-like immune cells may worsen asthma
Researchers at McMaster University have made an important discovery in the field of asthma research, identifying a new population of immune cells that may play a crucial role in the severity of asthma symptoms.
Jan 15, 2025
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Ultrasound-directed microbubbles could boost immune response against tumors
A new paper by a team of Concordia researchers from the departments of Biology and Physics proposes a novel method of fighting cancer tumors that uses ultrasound-guided microbubbles—a technology already widely used in medical ...
Jan 15, 2025
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Immune complex removes receptors from stem cells to protect against cancer, preclinical study finds
A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical ...
Jan 15, 2025
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