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Allergy and immunology news
In vivo CRISPR screen identifies gene edits that strengthen CAR-T therapy against solid tumors
For patients with blood cancers like leukemia and lymphoma, the immunotherapy known as CAR-T cell therapy can be lifesaving. Doctors remove a patient's immune cells, called T cells, engineer them in the lab to better recognize ...
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Dysregulated immune cells may cause silent inflammation after heart attack
Coronary artery disease, which is caused by plaque buildup in the arteries that supply blood to the heart, can appear stable for long periods without causing any symptoms. But the disease can become unstable at any time and ...
6 hours ago
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Scientists uncover drivers of recurrent arthritis after immunotherapy, suggesting potential biomarkers
A new study led by researchers at The University of Texas MD Anderson Cancer Center has shown that inflammatory arthritis occurring as a side effect of immune checkpoint inhibitors behaves like an immune-memory disease, suggesting ...
8 hours ago
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Humanized mouse model could significantly improve preclinical research on drugs for celiac disease
Celiac disease is an autoimmune disorder in which the immune system reacts to gluten. More than 1% of the population in Germany is affected. In these individuals, gluten proteins found in wheat, rye and barley trigger inflammation ...
8 hours ago
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Computational framework identifies novel pathway for asthma inflammation
Researchers at Columbia University Mailman School of Public Health, in collaboration with investigators at the University of Chicago, have developed a new computational framework that helps scientists identify genes that ...
Aug 11, 2026
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Cells' own abnormal RNA may trigger inflammation during viral infection, challenging 20 years of assumptions
New research led by the Hudson Institute of Medical Research has shown how a cell recognizes that it is infected with a virus to protect itself and surrounding cells or induce inflammation. The discovery, published in Nature ...
Aug 11, 2026
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Immune cells rely on a cholesterol sensor to maintain balance, researchers discover
Every day, billions of cells in our body die and are removed as part of normal tissue maintenance. This continuous cleanup process is essential for keeping the immune system in balance and preventing harmful immune reactions ...
Aug 11, 2026
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Brain immune cell map explains how defenses shift during Alzheimer's progression
The brain's immune cells are increasingly recognized as key players in Alzheimer's disease, but exactly how they change as the disease develops has remained unclear. A new study published in Nature Genetics provides the most ...
Aug 11, 2026
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Genetic variants shed light on kidney transplant rejection
Immunosuppressive medications help prevent organ rejection following transplantation, yet some patients still experience rejection despite receiving adequate treatment. New research from Yale, published in the Journal of ...
Aug 11, 2026
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Differences in immune cells predict skin cancer treatment outcomes
In a first-of-its-kind study by King's College London, researchers have linked changes in two major types of immune cells in blood to different survival outcomes for patients with melanoma. Melanoma, the fifth most common ...
Aug 11, 2026
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Sarcoidosis shifts lung immune-cell communication, single-cell data suggest
Researchers at National Jewish Health and partner institutions have discovered specific changes in immune cells in the lungs of people with sarcoidosis. Their findings help explain how this inflammatory disease develops and ...
Aug 11, 2026
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Solving a mysterious inflammatory fever opens the book on a much bigger story
Three research teams working independently around the world have landed on the same discovery: A single molecular "handshake" inside our cells controls a family of inflammatory diseases, including one of the most common inherited ...
Aug 10, 2026
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Molecular mapping reveals hidden cellular programs in heart transplant rejection
A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.
Aug 10, 2026
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HIV-1 proviruses may drive chronic systemic inflammation
HIV (human immunodeficiency virus) is a virus that attacks the body's immune system and remains a major global health challenge because of persistent viral reservoirs, despite effective treatments. Key factors include around ...
Aug 10, 2026
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New analysis explains why bone marrow cancer T cells may need therapeutic activation
A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow of patients ...
Aug 10, 2026
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How heatstroke kills—it can still be deadly after your body cools down
Europe is in the grip of yet another deadly heat wave. Over 10,000 excess deaths were recorded during late June 2026 alone—and the toll keeps climbing.
Aug 10, 2026
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Why the body's inflammatory alarm misfires in familial Mediterranean fever
Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease in which the body's own immune system overreacts to minimal or inappropriate stimuli, producing recurrent attacks of fever and painful inflammation. ...
Aug 7, 2026
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Early respiratory infections linked to atopic dermatitis diagnosis
Early respiratory infection burden is associated with atopic dermatitis (AD) diagnosis in childhood, according to a study published online July 29 in JAMA Dermatology.
Aug 7, 2026
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Study identifies promising therapy to prevent relapses in rare neurological disease
An international study led by Mayo Clinic researchers has identified interleukin-6 (IL-6) receptor blockers as a promising option for preventing relapses in myelin oligodendrocyte glycoprotein antibody-associated disease ...
Aug 7, 2026
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Deadly Candida auris hides in hair follicles by rewiring skin immunity
Since its discovery in Japan in 2009, a deadly fungus has emerged in hospitals around the world. The pathogen, known as Candida auris, lives silently on the skin. But it can be deadly if it reaches the bloodstream, killing ...
Aug 6, 2026
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Discovery reveals aging human brains receive immune cell reinforcements from blood
The brain's immune system has long been thought to exist independently from the rest of the body, complete with its own specialized immune cells and a blood-brain barrier that limits what can travel into the brain.
Aug 6, 2026
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Map of tonsil's genetic 'spaghetti' yields insights into immunity
About 2 meters (6.6 feet) of genetic material must fit into the nucleus of each of most of our trillions of cells, coiling and winding to form what looks like a tangled mess. But when genes are used, how they are used and ...
Aug 6, 2026
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Critical immune pathway may explain how skin allergies can trigger systemic reactions
The human body experiences allergic reactions when the immune system mistakenly overreacts to harmless substances, known as allergens, such as pollen, dust or certain foods. While this often causes mild symptoms such as sneezing ...
Aug 6, 2026
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A lesser-known SARS-CoV-2 protein may offer clues to long COVID symptoms
Six years after the height of the COVID-19 pandemic, scientists are still uncovering surprising ways the virus can wreak havoc on the body. A new UCLA study published in Science Advances describes a previously unrecognized ...
Aug 5, 2026
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