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Immunology news

Genetics

Improving research with more effective antibodies

A new study points to the need for better antibody validation, and outlines a process that other labs can use to make sure the antibodies they work with function properly.

Oncology & Cancer

Drug-light combo could offer control over CAR T-cell therapy

Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR T cells ...

Medical research

How to enable light to switch on and off therapeutic antibodies

When antigens such as a virus or bacteria invade our body, the immune system springs into action: it creates antibodies that stick to the antigens so that they can identify and destroy the intruders. Did you know that these ...

Diseases, Conditions, Syndromes

Drug reduces risk of pneumonia in newborn mice

The underdeveloped lungs and immune systems of premature babies put them at high risk of potentially deadly pneumonia. Now, a study from Washington University School of Medicine in St. Louis has found, in mice, that an inhaled ...

Oncology & Cancer

Drug shows promise as immune therapy for cancer

A therapy developed by Yale researchers stimulates immune cells to shrink or kill tumors in mice, according to a new study published in the Journal of Experimental Medicine. The therapy is effective alone or in combination ...

Immunology

Researchers unravel the early makings of an exhausted T cell

The immune system struggles to defeat cancer or chronic infections because many of the T cells that leap into action end up "exhausted," rendering them ineffective against disease. That path to exhaustion and what triggers ...

Oncology & Cancer

Scientists help immune system find hidden cancer cells

Cancer cells are masters at avoiding detection, but a new system developed by Yale scientists can make them stand out from the crowd and help the immune system spot and eliminate tumors that other forms of immunotherapies ...

Immunology

Birth weight linked to childhood allergies

The more a baby weighs at birth relative to its gestational age the greater the risk of childhood food allergies and eczema, according to South Australian researchers.

Immunology

A new regulator of B cell development

Interleukin-33 (IL-33) drives inflammatory responses in allergic and nonallergic disease. Epithelial cells in the lungs, gastrointestinal tract and elsewhere release IL-33, which activates the ST2 receptor on immune cell ...

Immunology

When studying immune cells, environment matters

For years, scientists have used cells grown in petri dishes to study the metabolic processes that fuel the immune system. But a new report in Immunity suggests looking outside the dish and into living organisms gives a drastically ...

Immunology

Gut immunity more developed before birth than previously thought

Most biology textbooks explain that the fetal immune system is largely undeveloped and that it learns after being exposed to the world at birth. New research from the University of Pittsburgh School of Medicine and UPMC Children's ...

Oncology & Cancer

Unique immune cell could help stop breast cancer

A unique type of immune cell has been discovered in human breast tissue, and breast cancer patients with more of these cells are more likely to survive, finds new research from the Francis Crick Institute and King's College ...

Oncology & Cancer

New mechanism fueling brain metastasis discovered at Wistar

Scientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant supporting cells in the brain, also promote cancer cell growth and metastasis in the brain.