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Immunology news

Oncology & Cancer

Cancer cells mediate immune suppression in the brain

Scientists have long believed that the brain protects itself from an aggressive immune response to keep down inflammation. However, that evolutionary control may work against it when a cancer cell attempts to spread to the ...

Genetics

Study identifies more genes that are likely behind psoriasis and eczema

A Swedish study has identified 17 new genes that could be targeted for treatment of psoriasis and eczema, two common hereditary skin diseases with no cure.

Health

Langerhans cells are up to the job, they just need a chance

Blood stem cell transplants are an important part of treatment for a variety of serious conditions. However, adverse reactions of the host to donor cells present a significant risk. Now, researchers from the University of ...

Medical research

New insights into a potential target for autoimmune disease

Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in striking this balance, acting ...

Genetics

Insights into the genetic architecture of penicillin allergy

Researchers announce the first robust evidence for the role of the major histocompatibility complex gene HLA-B in penicillin allergy. To identify genetic risk factors for penicillin allergy, the international team of researchers ...

Genetics

Cell-free DNA provides a dynamic window into health

Short fragments of cell-free DNA (cfDNA) that circulate in blood, urine, and other biofluids can offer an information-rich window into human physiology and disease. By looking at the methylation markers of cfDNA, researchers ...

Medical research

The unexpected repair function of neutrophils

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered that neutrophils, the most abundant cells of the innate immune system, have many more functions in the body than previously thought. ...

Oncology & Cancer

Taking the itch out of cancer immunotherapy

Using the body's immune system to fight cancer has great potential, but can also bring serious side effects, including itchy and painful skin reactions. But now, researchers from Japan have found how these skin reactions ...

Diseases, Conditions, Syndromes

SARS-CoV-2 antibodies detectable up to seven months post COVID-19 onset

A new study led by Marc Veldhoen, principal investigator at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) with an interdisciplinary team of clinicians and researchers from Faculdade de Medicina da Universidade ...

Genetics

Multiple sclerosis as the flip side of immune fitness

About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of the autoimmune disease ...

Diseases, Conditions, Syndromes

Can scientists take the STING out of common respiratory viruses?

University of North Carolina School of Medicine scientists have made a curious discovery about a well-known human protein that helps the immune system fight viral infections. The lab of Stan Lemon MD, and colleagues found ...