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Women are more prone to developing asthma, particularly more severe types of asthma, compared to men. Studies have shown that the sex hormones, estrogen and testosterone, influence the mechanisms driving airway inflammation ...
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Research at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) yielded new insights into the environment surrounding different types of lung tumors, and described how these complex cell ecosystems may in turn ...
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Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier—which keeps large molecules in the blood from entering the brain—becomes abnormally permeable, ...
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Researchers at The Wistar Institute have characterized the function of neutrophils, a type of white blood cells, during early stages of tumor progression, showing that they migrate from the bone marrow to distant sites and ...
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Walter and Eliza Hall Institute researchers have revealed how immune health is maintained by the exquisite organisation skills of a protein called Pax5.
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Researcher from the Institute of Biology, Leiden have discovered how good intestinal bacteria regulate our innate immune system. This surprising discovery could make it possible to treat diseases related to inflammation, ...
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Premature birth is the leading cause of infant death and disability in the U.S., and costs billions in dollars and heartache every year. Now, University of Connecticut researchers report in Reproductive Sciences a potential ...
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The adult lung consists of highly specialized cell types that are protected by a variety of immune cells. How these immune cells migrate to the lungs during development and after birth, and how these cells influence each ...
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A team of researchers from Switzerland, the U.S. and Spain has isolated an enzyme that triggers an autoimmune response from T-cells in patients with MS. In their paper published in the journal Science Translational Medicine, ...
A new UNC School of Medicine study shows that two cystic fibrosis (CF) drugs aimed at correcting the defected CFTR protein seem to be more effective when a patient's airway is inflamed. This is the first study to evaluate ...
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A research team led by Peter Sloot, professor of Complex Adaptive Systems at the University of Amsterdam, has managed to pinpoint the mechanisms behind the immune response triggered in patients undergoing open heart surgery. ...
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In a University of California, Irvine-led study, researchers found evidence that mast cells, an important group of immune cells typically associated with allergies, actually enable the body to survive fasting or intense exercise. ...
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Massachusetts General Hospital (MGH) physicians are reporting an unexpected side-effect from treatment with dupilumab, which is FDA approved for the treatment of moderate to severe eczema, also called atopic dermatitis. In ...
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In the autoimmune disease systemic lupus erythematosus or SLE, the immune system produces antibodies against parts of the body itself. How cells that produce those antibodies escape the normal "checks and balances" has been ...
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Around the globe, an estimated 235 million people suffer from asthma. Most people are able to manage their symptoms and live healthy, active lives. However, for some, current treatments are not effective. Managing symptoms ...
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Scientists at UC San Francisco have painstakingly assembled a searchable database of normal human immunity that researchers can now use as an instant comparison group in studies of the immune system and immune dysfunction. ...
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The complement proteins that circulate in our blood are an important part of our immune system. They help identify bacteria, viruses and other harmful organisms, making it easier for our white blood cells to find and neutralise ...
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Scientists at Scripps Research have discovered the role of an immune system double agent. This molecule, called USP18, can help curtail immune responses, but it can also open the door to bacterial infections, such as harmful ...
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At least 250 million people are infected with malaria every year, and about half a million of those die from the disease. A new study from MIT offers a possible explanation for why some people are more likely to experience ...
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A particular type of white blood cell becomes more pro-inflammatory as it deteriorates with age or 'senesce', according to research led by A*STAR scientists.
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A study from the Nationwide Children's Hospital analyzed environmental exposures, like pet and secondhand smoke, to determine if they have a role in asthma control among children whose asthma is managed per NAEPP (EPR-3) ...
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In a study published today in Science Translational Medicine, Mount Sinai researchers describe for the first time a mechanism that may shrink collections of immune cells in the gastrointestinal (GI) tract, called lymphoid ...
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Researchers want food labelling regulations tightened after their study found that some people with allergies had anaphylactic reactions to packaged foods.
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A group of expert panelists gathered to discuss "Thyroid Immune Testing—Guidelines, Testing Platforms, and Clinical Impact on Women's Health." The informative and enlightening results of the Roundtable discussion are presented ...
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Australian researchers have uncovered clues in the immune system that reveal how the balance of 'good' gut bacteria is maintained. The information could help in the prevention and treatment of inflammatory bowel disease (IBD).
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Researchers at MRC HIU examined the large intestine using sophisticated single cell technology, in work that paves the way for better treatments for IBD.
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This year's award of the Nobel Prize for Physiology and Medicine to James P. Allison and Tasuku Honjo, for their work in the early 1990s on immune checkpoint proteins CTLA4 and PD1, is a fitting recognition of how their work ...
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A single leukemia cell, unknowingly engineered with the leukemia-targeting chimeric antigen receptor (CAR) lentivirus and infused back into a patient, was able to reproduce and cause a deadly recurrence of B-cell acute lymphoblastic ...
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Inflammation is one strategy your body uses to fight infection, but if it gets out of control it can kill instead of heal. In the Sept. 18 issue of Immunity, UConn Health immunologist Vijay Rathinam and colleagues show how ...
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Disruption of the refill of patients' regular combination inhaled corticosteroid therapy brand may have impacted symptoms and disease control and potentially lead to an increased rate of costly exacerbations and hospitalizations.
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An unhealthy population of microbes in the mouth triggers specialized immune cells that inflame and destroy tissues, leading to the type of bone loss associated with a severe form of gum disease, according to a new study ...
After more than five years and 672 patient samples, an OHSU research team has published the largest cancer dataset of its kind for a form of leukemia. The study, "Functional Genomic Landscape of Acute Myeloid Leukemia", published ...
A drug first identified 150 years ago and used as a smooth-muscle relaxant might make tumors more sensitive to radiation therapy, according to a recent study led by researchers at The Ohio State University Comprehensive Cancer ...
Oct. 17, 2018—Scientists at Scripps Research have successfully tested a potential new smoking-cessation treatment in rodents.
One question that scientists and fitness experts alike would love to answer is whether exercise or nutrition has a bigger positive impact on bone strength.
A trio of researchers from the University of New South Wales and Western Sydney University has discovered some of the factors involved when people make errors in estimating the ages of other people. In their paper published ...
Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice. Instead of killing causative bacteria ...
The architecture of each person's brain is unique, and differences may influence how quickly people can complete various cognitive tasks.
The most common form of Mycobacterium tuberculosis (TB) originated in Europe and spread to Asia, Africa and the Americas with European explorers and colonialists, reveals a new study led by UCL and the Norwegian Institute ...
A perpetually unctuous, self-lubricating latex developed by a team of scientists in Boston could boost the use of condoms, they reported Wednesday in the journal Royal Society Open Science.
Traditional laxatives are recommended as first-line agents to treat patients with a confirmed diagnosis of opioid-induced constipation (OIC), according to a new guideline from the American Gastroenterological Association ...
A group of Massachusetts General Hospital (MGH) investigators is proposing that targeting immune checkpoints—molecules that regulate the activity of the immune system—in immune cells called microglia could reduce the ...
Two projects in which healthy individuals have had their genomes sequenced have revealed that searching for unanticipated genetic results in newborns and adults can unearth far more variants associated with diseases than ...
Researchers have discovered a novel consequence of loss of the tumour protein p53 that promotes cancer development, according to new findings in eLife.
Researchers have developed a new device that can be used to visualize how sound-induced vibrations travel through the ear. The technology is providing new insight into how the ear receives and processes sound waves and, with ...
Higher blood levels of omega 3 fatty acids found in seafood are associated with a higher likelihood of healthy ageing among older adults, finds a US study published by The BMJ today.
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