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Allergy and immunology news
22 million human immune cells help decode context-dependent gene circuits
Scientists from Gladstone Institutes, UC San Francisco and Stanford University, in collaboration with Biohub, have unveiled a massive, high-resolution functional map of human immune cells that promises to transform our understanding ...
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Three shifting immune states in sepsis could explain why treatments miss their window
Researchers have mapped how the immune response in people with sepsis changes over time. The work, led by King's College London, could help pave the way for treatments that target the specific parts of the immune system that ...
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Immune cells that drive harmful autoantibody responses after COVID-19 identified
When the immune system encounters a virus, it produces antibodies designed to recognize and eliminate the invader. But in some people infected with SARS-CoV-2, the virus that causes COVID-19, the immune response goes awry, ...
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Researchers develop scalable method to generate key immune cells for cancer therapy
Researchers at the Center for Regenerative Medicine (CReM) at Boston Medical Center (BMC) and Boston University (BU) have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells ...
18 hours ago
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Schizophrenia and mood disorders show different innate immune signatures, analysis finds
A team involving researchers from Wroclaw Medical University analyzed studies of people with schizophrenia spectrum disorders and mood disorders, including depression and bipolar disorder. They found that the two groups showed ...
23 hours ago
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Why do some people react so badly to mosquito bites? The answer lies in mosquito saliva
Two people spend an evening in the same garden and receive roughly the same number of mosquito bites. By morning, one barely notices them—while the other is covered in large, swollen, intensely itchy welts that linger for ...
Aug 27, 2026
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Male sex hormones may protect lungs from asthma by boosting nerve connections
The differences in male and female sex hormones are most evident during growth, puberty and reproduction, when they help shape how the body develops and functions. Beyond their more visible effects, these chemical messengers ...
How much the immune system sees may shape how well we fight infections
Why does the same infection cause only mild symptoms in one person but more serious disease in another? A new study led by the HUN-REN BRC Szeged Momentum Systems Immunology Research Group, together with several international ...
Aug 26, 2026
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Gut tissue may retain inflammatory 'memory' for more than a year
Every three to five days, the layer of cells lining our intestines is completely renewed—the fastest turnover rate in the human body. Such rapid regeneration is an absolute necessity for tissue that endures constant mechanical ...
Aug 26, 2026
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Experimental Zika vaccine reveals T cells can drive protection without antibodies
Zika virus has been spreading for decades, but it first grabbed worldwide headlines in 2016. That February, with an outbreak sweeping the Americas, the World Health Organization (WHO) declared the surge in Zika-linked birth ...
Aug 26, 2026
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AI and proteomics uncover seven blood proteins linked to vasculitis remission
Vasculitis is a disease in which the immune system mistakenly attacks blood vessel walls, causing them to become inflamed. If left untreated, the rare disease can severely damage organs, including the kidneys and lungs. Physicians ...
Aug 26, 2026
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Immune responses to urinary tract infection linked to birth outcomes
A study published in Science Translational Medicine shows that the increased risk of preterm birth associated with urinary tract infection (UTI) is linked to the body's immune response to the infection rather than to the ...
Aug 26, 2026
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How DNA folding controls immune gene activity in T cells
A new study by researchers at the Perelman School of Medicine at the University of Pennsylvania reveals that the three-dimensional folding of DNA at a key genetic locus helps determine when two related immune genes, Ets1 ...
Aug 26, 2026
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'Teacher cells' coated with tumor fragments train T cells to attack cancer in lab tests
The immune system possesses legions of T cells that, if primed, could hunt down and destroy tumors. Now, a UC San Francisco team has invented a way to do this by combining immune cells grown in the lab with samples from a ...
Aug 25, 2026
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Additional transfusion risk emerges for patients with tick-borne alpha-gal syndrome, beyond meat allergy
A new multi-institutional study led by researchers at Dartmouth Health and Geisel School of Medicine at Dartmouth suggests that alpha-gal syndrome, a tick-borne disease that can result in a chronic allergy to meat and animal ...
Aug 25, 2026
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Removing immune 'brake' improves CAR T-cell therapy for pediatric bone cancer
Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma. There is a great clinical ...
Aug 25, 2026
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New oral nanomedicine boosts effectiveness of cancer immunotherapies
Immune checkpoint blockade is a form of cancer treatment that works by releasing the natural brakes on the immune system, allowing T cells to find and destroy cancer cells. Although it has transformed cancer immunotherapy, ...
Aug 25, 2026
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Restoring aging T cell function to make them effective at fighting cancer
In a new study, Mass General Brigham researchers explore the causes of immune aging, a barrier to successful cancer immunotherapy, and identify a gene that may serve as an age-related prognostic marker and potential target ...
Aug 25, 2026
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Researchers map the development and behavior of B cells in melanoma
Researchers have created one of the most detailed maps to date of how white blood cells called B cells develop and behave inside melanoma tumors, a type of skin cancer. The study, led by King's College London and published ...
Aug 25, 2026
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Pollen season poses greater risk for people with COPD
Increased exposure to pollen negatively affects the lung function of people with chronic obstructive pulmonary disease (COPD), according to a new study in the July 2026 issue of Chronic Obstructive Pulmonary Diseases: Journal ...
Aug 25, 2026
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Small-molecule inhibitors shown to promote robust antitumor immunity
Researchers in Purdue University's College of Pharmacy have developed and validated a new series of small-molecule inhibitors that promote antitumor immunity and hold promise as anticancer agents.
Aug 24, 2026
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New fibroblast state reveals how lung tumors may suppress immune defenses
Researchers at Columbia University have identified a previously unknown population of fibroblasts that may protect lung tumors from immune attack. The work, published in Nature Immunology, illuminates a previously unknown ...
Aug 24, 2026
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Immunotherapy shows promise for clearing residual melanoma cells
Cornell researchers successfully ramped up the body's own immune response to fight melanoma at the tail end of targeted cancer therapy, when tumors commonly become resistant to these therapies and leave behind residual cancer ...
Aug 24, 2026
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New guidelines emphasize pollen monitoring for allergy management
Allergic rhinitis and asthma are among the most common chronic diseases today, affecting hundreds of millions of people worldwide. One contributing factor is climate change, which is extending pollen seasons, increasing pollen ...
Aug 24, 2026
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Macrophage 'molecular scissors' may drive obesity-linked inflammation and metabolic damage
Imagine the body's immune cells as a neighborhood cleanup crew. When all is healthy, macrophages roam tissues, clearing away cellular debris and helping maintain order. But obesity can turn these normally protective cells ...
