Immunology

Study explores role of metabolism in immune cell behavior

What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say ...

Oncology & Cancer

Immunotherapy and HDAC inhibition are anti-cancer besties

Immunotherapies have revolutionized the care of many cancers, teaching the body's own immune cells to recognize and attack tumor cells. Leading the way are drugs known as checkpoint inhibitors, which block a kind of "white ...

Immunology

Vaccine investigators use bacterium's own protein against it

A team of Agricultural Research Service (ARS) and university scientists is investigating a new "ingredient" for use in vaccinating cattle against Johne's disease, a chronic wasting affliction that costs the U.S. dairy industry ...

Genetics

Microbiome links diet to health

The composition of the human microbiome, a complex ecosystem of microorganisms, plays a crucial role in lifelong health. Little is known, however, about the detailed molecular mechanisms linking health status to the microbiome ...