Medical research

Microbiome: Untapped source of novel antimicrobials

Just as Gold Rush prospectors once mined the Northern California hills for the shiny precious metal, "bioprospectors" are searching for a new prize: potential antimicrobial molecules—and they are hunting them down in the ...

Oncology & Cancer

Clues to improve cancer immunotherapy revealed

Cancer immunotherapy drugs trigger the body's immune system to attack tumors and have revolutionized the treatment of certain cancers, such as lymphoma, lung cancer and melanoma. Yet, while some patients respond well to the ...

Oncology & Cancer

Inactive receptor renders cancer immunotherapies ineffective

The aim of immunotherapies is to enable the immune system to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one-third ...

Immunology

Creatine powers T cells' fight against cancer

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer, according ...

Immunology

Scientists identify genetic variation linked to severity of ALS

A discovery made several years ago in a lab researching asthma at Wake Forest School of Medicine may now have implications for the treatment of amyotrophic lateral sclerosis (ALS), a disease with no known cure and only two ...

Diseases, Conditions, Syndromes

Researchers study immune response to influenza

It is estimated that influenza (flu) results in 31.4 million outpatient visits each year. New research from the University of Minnesota Medical School provides insights into how the body can protect itself from immunopathology ...

Immunology

New treatment may reverse celiac disease

Results of a new phase 2 clinical trial using technology developed at Northwestern Medicine show it is possible to induce immune tolerance to gluten in individuals with celiac disease. The findings may pave the way for treated ...

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