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Clinical pharmacology news
Viagra's cousin could help muscle cells stay primed for regeneration
Tadalafil is a prescription drug closely related to Viagra. It is used to treat erectile dysfunction (ED) and the urinary symptoms of an enlarged prostate. Both competitive and recreational athletes sometimes use it too, ...
16 hours ago
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Wireless neural chip tracks brain changes in real time after Alzheimer's drug administration
A joint research team led by KAIST has used a small, implantable neural chip to wirelessly monitor real-time changes in a neurotransmitter involved in memory and learning after an Alzheimer's drug has been administered. In ...
19 hours ago
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Next-generation drug reduces endometrial cancer progression and death in trial
A new drug is effective at decreasing the recurrence of, and death from, endometrial cancer, an international study shows. The drug, called sacituzumab tirumotecan (sac-TMT), attaches to a protein on the surface of tumor ...
21 hours ago
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Treatment revives old liver cells in lab study, may help prevent Alzheimer's and heart disease
The liver's job of clearing harmful substances from the body is so essential that the organ may have implications for addressing unexpected diseases, including Alzheimer's and heart disease. A promising example comes from ...
21 hours ago
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Heart drug combo reduces kidney damage in septic shock surgery, major trial finds
A simple adjustment to drugs given during operations for septic shock could prevent thousands of patients from suffering kidney damage, according to the results of a major trial now published in JAMA. Scientists from the ...
20 hours ago
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Large meta-analysis sheds new light on how SGLT2 inhibitors affect blood and iron parameters
Research led by internist-nephrologist Dr. Michele Eisenga shows that SGLT2 inhibitors, a class of drugs widely used to treat type 2 diabetes, heart failure and chronic kidney disease, consistently increase hemoglobin and ...
14 hours ago
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Reproductive health and cystic fibrosis: New guidance offers options and hope
For much of the history of cystic fibrosis (CF) care, reproductive health was not a major part of the conversation. Fertility challenges were the norm for men and women with this genetic disorder, and many grew up assuming ...
19 hours ago
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Patient-reported outcomes worse for patients with rheumatoid arthritis discontinuing TNF inhibitor
For patients with rheumatoid arthritis (RA), patient-reported outcomes (PROs) generally worsen shortly after tumor necrosis factor inhibitor (TNFi) discontinuation, according to a study published in the Journal of Rheumatology.
21 hours ago
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Can psychedelics soothe an overactive immune system? New meta-analysis investigates
The same substances that can alter perception and shift moods are now drawing scientific interest for their potential therapeutic abilities. Researchers across the globe are investigating whether psychedelics, such as psilocybin ...
Creating 'satellite maps' of thousands of proteins across tissue could transform drug therapies
Much like a satellite provides a full picture of Earth, a new technology can generate thousands of detailed "satellite maps" showing where individual proteins are located and distributed across an entire tissue in the body ...
Oct 24, 2026
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Ebola vaccine trial begins in DR Congo
The first clinical trial of an Ebola vaccine in the outbreak gripping the Democratic Republic of Congo began Friday, the head of the World Health Organization said.
Oct 24, 2026
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How psilocybin reshapes brain circuits
A new study led by researchers at the University of California, Santa Cruz, reveals how psilocybin, the psychoactive compound in "magic mushrooms," reshapes neural connections in the brain.
Oct 23, 2026
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Cancer cells' own carbon monoxide fuels anticancer drug production in lab tests
What if we could use a cancer's own byproduct to make drugs that destroy tumor cells from the inside? That is what Katsunori Tanaka and his team have done at the RIKEN Pioneering Research Institute (PRI) in Japan.
Oct 23, 2026
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Once-daily oral icotrokinra outperforms placebo in ulcerative colitis
For patients with moderately to severely active ulcerative colitis, oral icotrokinra, a peptide that blocks the interleukin-23 receptor, yields a clinical response at week 12 significantly more often than placebo, according ...
Oct 23, 2026
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Tegoprubart preserves kidney function better than tacrolimus in first-time transplant patients, trial suggests
The phase 2 BESTOW clinical trial showed that tegoprubart (a novel anti-CD40L antibody therapy) was better at preserving kidney function than tacrolimus (the current standard of care) in immunosuppressive regimens in adults ...
Oct 23, 2026
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Standard kidney function tests underestimate chronic kidney disease in people with cancer
New research indicates that commonly used measures of kidney function underestimate the prevalence of chronic kidney disease (CKD) in patients with cancer. The findings will be presented at ASN Kidney Week 2026, Oct. 22–25.
Oct 23, 2026
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FDA approves hepatitis B shot that may let some patients stop all treatment
Some adults with chronic hepatitis B may now have a path to something today's treatments rarely deliver—stopping all medication while the virus stays in check.
Oct 23, 2026
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Study finds patients experienced rapid weight gain after starting antipsychotic medication
People with severe mental illness experienced more rapid increases in both weight and long-term blood sugar levels during the first three months after starting treatment with antipsychotic medication, according to a study ...
Oct 23, 2026
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Lab study shows needle-free mRNA vaccine protects against COVID and flu
A needle-free vaccination method protected mice against the viruses that cause COVID-19 and flu, offering a possible new way to deliver mRNA vaccines while limiting unwanted inflammation.
Oct 22, 2026
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Rebalancing the body's cellular communication system could slow aging
Researchers have outlined a plan for slowing aging by targeting one of the body's most important cellular communication systems. In a new paper published in Frontiers in Science, scientists describe how novel therapies that ...
Oct 22, 2026
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Common multiple sclerosis treatment linked to bowel disease risk
People with multiple sclerosis (MS) who are treated with rituximab have an increased risk of developing inflammatory bowel disease, particularly Crohn's disease, although the absolute risk remains low. This is according to ...
Oct 22, 2026
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International study helps support FDA approval of HIV drug for newborns
An international study conducted through the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network, including researchers at the University of California San Diego, helped inform the U.S. Food ...
Oct 22, 2026
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Clinical trials generate promising results for improving kidney health
The results of numerous high-impact Phase III clinical trials that could affect kidney-related medical care were presented in person at American Society of Nephrology Kidney Week 2026, Oct. 22–25.
Oct 22, 2026
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ADHD medication unlikely to raise risk of self-harm, international study finds
The risk of self-harm among people with attention deficit hyperactivity disorder (ADHD) is highest before people start ADHD medication, rather than after treatment begins, according to new research led by Aston University ...
Oct 22, 2026
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New AI platform helps uncover promising cancer drug combinations
UCLA investigators have developed a new artificial intelligence-based platform that could help scientists identify promising drug combinations to overcome treatment resistance in cancer.
Oct 22, 2026
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