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Clinical pharmacology news
Newly identified molecule could help regulate sleep
Sleep is known to be essential for survival, as it allows both humans and other animals to rest, while the brain consolidates memories and clears out metabolic waste products. For many people worldwide, however, falling asleep ...
4 hours ago
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Nearly all countries overuse powerful antibiotics, global study finds
Certain antibiotics are overused in most countries, while too few people receive the specific antibiotic treatments they need, according to a study of antibiotic use across 186 countries published in The Lancet Public Health ...
5 hours ago
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One in ten medicines worldwide could be fake or substandard—here's how to protect yourself
Anyone who has bought medicine online may have wondered whether what arrived in the mail was really what they had paid for. They are not alone. A recent global survey found that around 60% of people fear their medicines could ...
4 hours ago
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Availability of generic semaglutide removes barrier to affordable diabetes care, experts predict
In a novel analysis examining the economic implications of generic semaglutide entering the Canadian market, researchers predict that anticipated price reductions of up to 70% will dramatically increase both the cost-effectiveness ...
13 hours ago
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Druggable target that makes metastatic cancer cells easier to kill identified
Researchers at the University of Illinois Chicago have identified a molecular switch that helps determine whether cancer cells remain soft and difficult to destroy or become stiff enough for the immune system to attack.
20 hours ago
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New protein structure reveals cancer signaling mechanism and potential drug target
Malignant melanoma is one of the most dangerous forms of cancer. Around half of melanomas and about 7% of all other cancers carry a mutation in a protein called BRAF. This mutation disrupts the regulation of cell division, ...
19 hours ago
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Semaglutide sustains lower calorie intake for more than a year, study shows
People taking semaglutide for weight loss continued to consume significantly fewer calories after 60 weeks on the medication, helping explain how the medication supports both initial weight loss and long-term weight maintenance. ...
21 hours ago
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2018 to 2024 saw rise in insurance denials for brand-name drugs
Insurance denials of initial attempts to fill brand-name prescription drugs with no generic competitors increased by more than two-thirds from 2018 to 2024, according to a study published online in the Journal of the American ...
17 hours ago
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Newer obesity drugs linked to fewer alcohol-related hospitalizations for people with alcohol dependence
Use of newer GLP-1 receptor agonists (semaglutide or tirzepatide) for obesity or diabetes among people with alcohol use disorder was associated with a reduction in alcohol-related hospital admissions, according to a study ...
19 hours ago
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Healthy aging supplement shows limited benefits in older adults with cognitive impairment
Nicotinamide adenine dinucleotide, or NAD+, is all the rage in the healthy aging space. Social media influencers tout NAD+ supplements, injections and infusions as anti-aging miracles that can clear brain fog and improve ...
23 hours ago
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Viagra may reduce cancer metastasis, study shows
Viagra was originally developed to treat high blood pressure and chest pain caused by reduced blood flow to the heart, but over the past three decades it has become the world's best-known therapy for erectile dysfunction. ...
Jul 21, 2026
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One of the oldest psychedelics meets modern brain imaging
For millennia, people have used the psychedelic mescaline as a spiritual and religious tool. Mescaline is a naturally occurring chemical found in cacti, mainly peyote cacti, that are located in the Southwest United States ...
Jul 21, 2026
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Aspirin matches costlier blood thinners after hip and knee replacement surgery, major trial finds
Joint replacements are among the most common surgeries worldwide, and preventing blood clots is critical to recovery. A Dalhousie-led study published this month—one of the most robust of its kind to date—found that a straightforward ...
Jul 20, 2026
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Review calls attention to brain development risks associated with certain medications during pregnancy
A review article by a University of Nebraska Medical Center/Child Health Research Institute research team underscores how altering fundamental brain development processes can harm the developing fetus. The publication suggests ...
Jul 20, 2026
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COVID-19 vaccines remain effective despite helminth-induced immune modulation
More than a quarter of the world's population is affected by helminth infections, which can profoundly alter the immune system. In a preclinical study, researchers found that mRNA- and protein-based SARS-CoV-2 vaccines effectively ...
Jul 20, 2026
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Clinical trial: Oral drug keeps cancer treatment on track for patients who develop persistently low platelet counts
In a phase 2 clinical trial, Mass General Brigham Cancer Institute researchers found that the oral drug avatrombopag was safe and effective in managing persistent chemotherapy-induced thrombocytopenia (CIT) in more than half ...
Jul 20, 2026
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Researchers study barriers to GLP-1 insurance coverage
Despite growing evidence that GLP-1 medications improve health and are worth their cost, many insurance plans still limit coverage. University of Mississippi researchers are examining why and where that leaves patients.
Jul 20, 2026
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Ozempic-like drugs found to be safe and effective for children with obesity, without diabetes
New research being presented at the International Congress on Obesity (ICO2026), hosted by the World Obesity Federation (WOF) in Mexico City, Mexico (15–17 July), shows that glucagon-like peptide-1 receptor agonists (GLP-1 ...
Jul 20, 2026
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ER opioid prescriptions unlikely to be significant drivers of future substance use among adolescents
The pendulum may have swung too far in the direction of caution when it comes to limiting opioids for adolescents who are in pain, according to new research from a University of Alberta emergency medicine team published in ...
Jul 20, 2026
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Q&A: Psychedelics, cannabis, GLP-1s and drug policy changes
From headlines and social media, psychedelic therapies, cannabis use and GLP-1 medications have seemingly become commonplace overnight, but the science underlying these treatments and the pathway to drug approval are often ...
Jul 20, 2026
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Keeping drugs free of contaminants—pharmaceutical manufacturers filter medications through tiny pores
Every year, the global pharmaceutical industry produces trillions of doses of medications. Manufacturing these drugs involves several stages, and the chance of contamination increases with every step.
Jul 20, 2026
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No link between acetaminophen use during pregnancy and adverse birth outcomes, study finds
There is no statistically significant evidence that taking acetaminophen, also known as Tylenol, during pregnancy negatively affects how early a child is born or a child's birth weight, according to new research led by environmental ...
Jul 20, 2026
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Novel antifungal drug shows promise in some patients with Valley Fever
A subanalysis of a single-group, open-label, Phase IIb study found that olorofim, a first-in-class orotomide antifungal agent that does not have U.S. FDA approval, showed efficacy in patients with disseminated coccidioidomycosis ...
Jul 20, 2026
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Cancer survivors and providers differ in views on medical cannabis, study finds
For many cancer survivors, cannabis has become part of how they manage symptoms such as pain, nausea and anxiety. Medical cannabis is now legal in 47 states, Washington, D.C., and three U.S. territories, and its use continues ...
Jul 18, 2026
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Early warning signs of potential drug resistance in schistosomiasis parasite revealed
Scientists have identified genetic changes in wild populations of the parasitic worm that causes schistosomiasis that may reduce its response to praziquantel, the only available treatment. The study provides an early warning ...
Jul 17, 2026
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