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Clinical pharmacology news
Breast cancer study reveals synergistic effect of CDK2 and CDK4/6 combination therapy
A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously ...
12 hours ago
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Iron supplements restore muscle strength in mouse model of muscular dystrophy
Researchers at Kumamoto University have demonstrated that iron supplementation can significantly alleviate muscle pathology and functional decline in a mouse model of facioscapulohumeral muscular dystrophy (FSHD), a rare ...
9 hours ago
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Automated 3D heart tissue platform speeds up cardiac drug testing
Researchers from Leiden University Medical Center (LUMC) and the Leiden-based biotech company Ncardia have joined forces to develop a new platform that enables the automated production of 3D cardiac microtissues. This platform ...
13 hours ago
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Enzyme-blocking treatment reverses chronic pain in preclinical study
Chronic pain affects more than 50 million Americans, yet for decades, treatment options for pain that persists in the absence of inflammation have been limited. Seventy-five percent of these patients, disproportionately women, ...
16 hours ago
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Helping people with dementia have a say in their medical care
A new resource is helping people with dementia speak to their doctors and health care professionals about their medicines with more confidence.
10 hours ago
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Study reveals weight loss medications may improve outcomes for chronic sinus disease patients
A new study published in Otolaryngology–Head and Neck Surgery reveals that glucagon-like peptide-1 receptor agonists (GLP-1RAs)—a class of medications primarily used for weight loss and diabetes management—may significantly ...
15 hours ago
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GLP-1 medications: A comprehensive overview
With more studies emerging, GLP-1 and dual GIP/GLP-1 medications have become well-established options for those with obesity or type 2 diabetes.
18 hours ago
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Psilocybin could treat depression via a non-hallucinogenic receptor
Psychedelics, psychoactive substances that alter people's perceptions, mood and thought patterns, have recently shown promise for the treatment of some mental health disorders, including depression and substance use disorders ...
Treating psoriasis without side effects: Light-activated molecules demonstrate potential
Researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish National Research Council (CSIC) have developed a series of light-activatable drug candidates that could serve as a potential treatment ...
Jan 21, 2026
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Lithium study yields insights in the fight against HIV
Lithium, a widely used treatment for bipolar disorder and other mood disorders, has shown early promise in suppressing HIV, McGill University researchers report.
Jan 21, 2026
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Pharmacy professor develops AI model to predict hospitalization of at-risk cardiac patients
When Arinze Nkemdirim Okere, PharmD, MBA, worked as the pharmacist for a hospital in Tallahassee, Florida, he noticed that discharged patients would regularly return, often for issues that could have been easily treated.
Jan 21, 2026
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Scientists identify promising new target for Alzheimer's-linked brain inflammation
A multidisciplinary team has developed a selective compound that inhibits an enzyme tied to inflammation in people at genetic risk for Alzheimer's, while preserving normal brain function and crossing the blood-brain barrier.
Jan 21, 2026
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Long term use of anti-acid drugs may not increase stomach cancer risk
The long-term use of proton pump inhibitors (PPIs), a class of drugs widely used to treat acid reflux and ulcers, may not be linked to any increased risk of developing gastric (stomach) cancer, finds a study of Nordic health ...
Jan 21, 2026
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What should I do with unused or expired prescription medications?
If you have unused or expired medication, the best thing is to dispose of it. Many people hang on to them, and this just creates opportunity for things to go wrong.
Jan 21, 2026
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FDA approves first treatment for Menkes disease in children
The U.S. Food and Drug Administration has approved the Zycubo (copper histidinate) injection as the first treatment for Menkes disease in pediatric patients. Approval of Zycubo was granted to Sentynl Therapeutics.
Jan 21, 2026
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Potential new target to treat Parkinson's disease discovered
About 1 million Americans suffer from Parkinson's disease, with around 90,000 new cases diagnosed each year, according to the Parkinson's Foundation. The chronic, degenerative brain disorder destroys dopamine-producing cells ...
Jan 20, 2026
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Certain antibiotics may may boost immune system
Research led by Lancaster University has discovered that a class of antibiotics—fluoroquinolones—can directly alter the potential bacterial killing ability of one of our immune cells called the macrophage.
Jan 20, 2026
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Cancer patients warned popular supplement may interfere with treatment
For many cancer patients, hair loss is one of the most distressing side effects of their therapy. Increasingly, they have been taking oral supplements of biotin, which are marketed to consumers for their potential to improve ...
Jan 20, 2026
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Study finds more men taking multiple medications
Research tracking polypharmacy—people regularly taking five or more medications—found an increase in multiple medicine use during the past decade, largely driven by a growth among men.
Jan 20, 2026
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New research identifies key strategies for global drug safety studies
A new study published in Therapeutic Innovation & Regulatory Science provides crucial insights into the design and implementation of multi-national observational studies for post-marketing drug safety assessment, addressing ...
A new strategy to beat lung cancer: Chemists develop first-in-class inhibitor targeting a key epigenetic regulator
A research team has made a breakthrough in epigenetic drug discovery. The researchers have successfully developed a first-in-class chemical inhibitor that precisely and selectively targets the ATAC complex, a critical cellular ...
Jan 19, 2026
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Drug used for blood disorders may aid recovery in severe malaria, study finds
A new clinical trial led by QIMR Berghofer, in collaboration with University of Sunshine Coast Clinical Trials Network has found a medication currently used for some blood disorders could help the body fight malaria more ...
Jan 19, 2026
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Small molecules could treat Crohn's disease by mimicking a protective gene variant
An estimated 3 million Americans have an inflammatory bowel disease (IBD) such as Crohn's disease or ulcerative colitis. But a lucky few individuals are far less likely to develop IBD because they have a rare variant of a ...
Jan 19, 2026
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New coffee chemicals show promise for managing type 2 diabetes
Coffee may do more than boost energy. New research suggests that certain compounds found in roasted coffee beans could help slow how quickly sugar enters the bloodstream, a finding that could one day support new foods aimed ...
Jan 19, 2026
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No short cuts—but a bit of sugar—in the quest to fight cancer relapse
Medical researchers typically play the long game, spending years (and years and years) exploring an idea that could move beyond the laboratory to improve human life. At Virginia Commonwealth University, Umesh Desai, Ph.D., ...
Jan 19, 2026
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