Experts develop immune-enhancing therapies to target tuberculosis
Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease. ...
9 hours ago
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Making transfusion-transmitted malaria in Europe a thing of the past
The current strategy used in Europe to mitigate malaria transfusion risk is efficient with just 10 reported cases over the 20 past years. However, current serological tests used to identify "at risk" donors are not sensitive ...
9 hours ago
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Preventing high rate of chronic lung disease in world's Indigenous Peoples begins at pre-conception, say researchers
Public health strategies must begin at pre-conception and early childhood to attain optimum lung function for the world's Indigenous Peoples who bear a higher burden of chronic respiratory disease, say an international research ...
14 hours ago
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US approves gene therapy treatment for hemophilia
Pharmaceutical giant Pfizer has received US approval for a gene therapy against a form of hemophilia, a rare and inherited blood clotting disorder, the company said Friday.
17 hours ago
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Vaccines have a crucial role in tackling antimicrobial resistance
Antimicrobial resistance is a leading cause of death and disability worldwide. In 2019, it caused over 1 million deaths globally and was linked to almost 5 million.
15 hours ago
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Study reports new compound that halts replication of COVID by targeting 'Mac-1' protein in cell models
Research appearing in the Journal of Medicinal Chemistry shows for the first time SARS-CoV-2, the virus responsible for COVID-19, can be inhibited from replicating in living cell cultures using a compound that targets "Mac-1," ...
Apr 25, 2024
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Researchers publish final results of key clinical trial for gene therapy for sickle cell disease
In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) ...
Apr 25, 2024
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Study confirms effectiveness of bivalent COVID-19 vaccine
A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to ...
Apr 25, 2024
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Study reveals racial disparities in COVID-19 testing delays among health care workers
At the height of the pandemic, timely access to COVID-19 testing was crucial for curbing the spread of the disease and informing treatment decisions. Studies have unveiled racial and ethnic disparities in COVID-19 infection ...
Apr 25, 2024
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Treatment for deadly superbug C. diff may be weakening
The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research from the University of Houston ...
Apr 25, 2024
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Improving health communication to save lives during epidemics
During epidemics of Ebola, COVID-19, Zika and other public health emergencies, effective communication of public health messages is crucial to control the spread of disease, maintain public trust, and encourage compliance ...
Apr 25, 2024
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Antimicrobial-resistant hospital infections remain at least 12% above pre-pandemic levels, study finds
Despite progress in combating antimicrobial resistance (AMR) in the U.S. since its peak during the COVID-19 pandemic, hospital-acquired AMR infections remain well above pre-pandemic levels, according to a major new study ...
Apr 25, 2024
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Study: Antibiotic use in patients hospitalized with COVID-19 appears to have no beneficial effect on clinical outcomes
Antibiotic treatment of adults hospitalized with moderate COVID-19 is associated with clinical deterioration, despite the drugs being given to over 40% of patients, according to new research being presented at this year's ...
Apr 25, 2024
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Researcher discusses importance of communicating to the public during a pandemic, and the personal risk it can entail
In global crises like the COVID-19 pandemic, it is vital that scientists step forward to engage with the public and help deliver medical and scientific advice in a friendly, digestible and open format. While the traditional ...
Apr 25, 2024
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Study reports chlamydia and gonorrhea more likely to be treated per CDC guidelines in certain populations
Chlamydia and gonorrhea are the two most common sexually transmitted infections (STIs) in the United States, impacting 2.4 million in 2021, and the number is rising.
Apr 25, 2024
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Study uncovers drug target in a protein complex required for activation of NF-κB
A new paper by Dana-Farber Cancer Institute scientists lays the foundation for targeted therapies to inhibit the activation of nuclear factor kappa B (NF-κB), a transcription factor that plays a role in various autoimmune ...
Apr 25, 2024
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Q&A: Scientist who helped design R21 anti-malaria vaccine reflects on 30 years of research, and what it promises
Until three years ago nobody had developed a vaccine against any parasitic disease. Now there are two against malaria: the RTS,S and the R21 vaccines.
Apr 25, 2024
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New tool helps identify babies at high risk for RSV
A new tool to identify infants most at risk for severe respiratory syncytial virus (RSV) illness could aid pediatricians in prioritizing children under age 1 to receive a preventive medication before RSV season (October-April), ...
Apr 25, 2024
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