Artemisinin, a potent anti-malarial drug, has been widely hailed as a promising alternative cancer treatment. Scientists from the National University of Singapore (NUS) recently showed that its anti-cancer properties could ...
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Data released today from the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) show that the HIV epidemic is coming under control in Lesotho. These results add to prior PEPFAR-supported Population-based HIV Impact ...
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(HealthDay)—When pop star Selena Gomez revealed Thursday that she had a kidney transplant, she put the autoimmune disease lupus in the spotlight.
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Flooding unleashed by three months of torrential rain in Niger has killed at least 54 people and left nearly 200,000 displaced, the UN said Friday.
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Fewer children are dying before their fifth birthday and although humans are living longer than ever before, one in five deaths last year were linked to poor diet, researchers said Friday.
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Countries have saved more lives over the past decade, especially among children under age 5, but persistent health problems, such as obesity, conflict, and mental illness, comprise a "triad of troubles," and prevent people ...
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PATH's Malaria Vaccine Initiative (MVI) and the US Department of Defense's Walter Reed Army Institute of Research (WRAIR) announced today that vaccinations are under way in a clinical trial to evaluate modifications to the ...
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A mother and infant in Malawi have the same repertoire of antibodies to Plasmodium falciparum, the malaria parasite. That suggests that boosting the mother's immune response to malaria, as via vaccination, will result in ...
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Malaria, one of the most severe public health problems, affected 212 million people worldwide in 2015. This life-threatening disease is caused by parasites that are transmitted to humans through the bites of infected female ...
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Malaria is a leading cause of death for children living in Sub-Saharan Africa. Many children in rural areas seek care at local community health clinics, but these clinics lack reliable tests to distinguish severe and uncomplicated ...
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Italian prosecutors have opened a manslaughter inquiry into the death of a four-year-old girl who was killed by malaria in northern Italy in a medical mystery that has gripped the country.
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Italy's health ministry has ordered an investigation into the death of a 4-year-old girl from malaria after checks determined she hadn't traveled to any country at risk for the disease.
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A four-year old girl has died of malaria after apparently contracting the disease in northern Italy in a case that has perplexed the medical world, doctors said Tuesday.
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Tulane University researchers have developed a new drug that is effective against non-severe cases of malaria, according to results from an FDA-supervised clinical trial published in the latest issue of The Lancet Infectious ...
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Niger has launched a campaign to destroy mosquito breeding sites in the capital in the wake of heavy rains that have lashed the city since June.
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Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases progressing to coma or death. It is widespread in tropical and subtropical regions, including much of Sub-Saharan Africa, Asia, and the Americas.
Five species of Plasmodium can infect and be transmitted by humans. Severe disease is largely caused by Plasmodium falciparum while the disease caused by Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae is generally a milder disease that is rarely fatal. Plasmodium knowlesi is a zoonosis that causes malaria in macaques but can also infect humans.
Malaria transmission can be reduced by preventing mosquito bites by distribution of mosquito nets and insect repellents, or by mosquito-control measures such as spraying insecticides and draining standing water (where mosquitoes breed). Despite a clear need, no vaccine offering a high level of protection currently exists. Efforts to develop one are ongoing. A number of medications are also available to prevent malaria in travelers to malaria-endemic countries (prophylaxis).
A variety of antimalarial medications are available. Severe malaria is treated with intravenous or intramuscular quinine or, since the mid-2000s, the artemisinin derivative artesunate, which is superior to quinine in both children and adults. Resistance has developed to several antimalarial drugs, most notably chloroquine.
There were an estimated 225 million cases of malaria worldwide in 2009. An estimated 655,000 people died from malaria in 2010, a 5% decrease from the 781,000 who died in 2009 according to the World Health Organization's 2011 World Malaria Report, accounting for 2.23% of deaths worldwide. Ninety percent of malaria-related deaths occur in sub-Saharan Africa, with ~60% of deaths being young children under the age of five. Plasmodium falciparum, the most severe form of malaria, is responsible for the vast majority of deaths associated with the disease. Malaria is commonly associated with poverty, and can indeed be a cause of poverty and a major hindrance to economic development.
This text uses material from Wikipedia licensed under CC BY-SA
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