It's late when we reach Inhamízua on the outskirts of the city.
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Left untreated, malaria can progress from being mild to severe—and potentially fatal—in 24 hours. So researchers at the University of British Columbia developed a method to quickly and sensitively assess the progression ...
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Researchers at Duke University have proposed a new mechanism for stimulating insecticide development to prevent the spread of deadly tropical diseases. The system is based on their similar proposal that has been spurring ...
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Pietro Ceccato remembers his first trip three years ago to a Maasai village located a two hour's drive south of Arusha, Tanzania. He was there with a team of public health researchers to learn more about the dynamics of trypanosomiasis, ...
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Gene editing is getting fresh attention thanks to a successful lab experiment with human embryos. But for all the angst over possibly altering reproduction years from now, this technology already is used by scientists every ...
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Dehydration is one of the most common causes of death among young children in the developing world – particularly during the hot summer months. ETH Professor Walter Karlen and his team of researchers have developed an inexpensive ...
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Collated Childhood cancer statistics in sub Saharan Africa have been published for the first time as a monograph in the peer reviewed journal ecancermedicalscience, allowing researchers and policymakers a critical new insight ...
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In order for cancer cells to successfully spread and multiply, they must find a way to avoid the body's own immune system. Scientists at the German Cancer Research Center have published an explanation for how this occurs ...
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Today, World Hepatitis Day, marks the first time that the global health community has come together to officially begin moving towards the elimination of viral hepatitis by 2030.
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Many cancer patients are susceptible to potentially lethal weight loss. Now researchers understand better why this happens, and perhaps how to prevent the condition. "Our goal is to know more about what happens in cancer ...
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Progress in beating back the AIDS epidemic risks being eroded by a funding shortfall set to grow under Donald Trump's proposed cuts to global health projects, experts and campaigners warned ahead of a major HIV conference.
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Schools that provide prevention education, insecticide-treated nets and antimalarial treatment, in regions where malaria is highly seasonal, could reduce the risk of schoolchildren developing anaemia and improve their cognitive ...
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An international research collaborative is testing a new approach to malaria vaccine development in humans for the first time. The concept is similar to that used by Edward Jenner to develop a vaccine against smallpox, the ...
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The National Institutes of Health has renewed a major grant that funds a University of Washington-led research center to understand malaria in India.
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A quarter of countries in sub-Saharan Africa receive very little funding for research into malaria despite having high malaria-related death rates.
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Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases progressing to coma or death. It is widespread in tropical and subtropical regions, including much of Sub-Saharan Africa, Asia, and the Americas.
Five species of Plasmodium can infect and be transmitted by humans. Severe disease is largely caused by Plasmodium falciparum while the disease caused by Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae is generally a milder disease that is rarely fatal. Plasmodium knowlesi is a zoonosis that causes malaria in macaques but can also infect humans.
Malaria transmission can be reduced by preventing mosquito bites by distribution of mosquito nets and insect repellents, or by mosquito-control measures such as spraying insecticides and draining standing water (where mosquitoes breed). Despite a clear need, no vaccine offering a high level of protection currently exists. Efforts to develop one are ongoing. A number of medications are also available to prevent malaria in travelers to malaria-endemic countries (prophylaxis).
A variety of antimalarial medications are available. Severe malaria is treated with intravenous or intramuscular quinine or, since the mid-2000s, the artemisinin derivative artesunate, which is superior to quinine in both children and adults. Resistance has developed to several antimalarial drugs, most notably chloroquine.
There were an estimated 225 million cases of malaria worldwide in 2009. An estimated 655,000 people died from malaria in 2010, a 5% decrease from the 781,000 who died in 2009 according to the World Health Organization's 2011 World Malaria Report, accounting for 2.23% of deaths worldwide. Ninety percent of malaria-related deaths occur in sub-Saharan Africa, with ~60% of deaths being young children under the age of five. Plasmodium falciparum, the most severe form of malaria, is responsible for the vast majority of deaths associated with the disease. Malaria is commonly associated with poverty, and can indeed be a cause of poverty and a major hindrance to economic development.
This text uses material from Wikipedia licensed under CC BY-SA
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