Ebola virus is a continuing threat in Central and West Africa, with an outbreak currently taking place in the Democratic Republic of Congo. The disease kills up to 90% of the people who get infected, and more than 150 people ...
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A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process—changes in mammary glands to accommodate breastfeeding—uses a molecular process believed ...
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Mounting a collaborative, real-time response to a Lassa fever outbreak in early 2018, doctors and scientists in Nigeria teamed up with researchers at Broad Institute of MIT and Harvard and colleagues to rapidly sequence the ...
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A breakthrough in monkey malaria research by University of Otago scientists encouraged the Bill & Melinda Gates Foundation to fund a special meeting in Dunedin recently.
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A novel study reports an innovative approach for developing a vaccine against Plasmodium vivax, the most prevalent human malaria parasite outside sub-Saharan Africa. The study led by Hernando A. del Portillo and Carmen Fernandez-Becerra, ...
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More than one million people die annually from cerebral malaria, the most lethal form of the disease. A recent study, led by Yale investigators, explores the role of glucose metabolism in the development of the disease, and ...
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At least 250 million people are infected with malaria every year, and about half a million of those die from the disease. A new study from MIT offers a possible explanation for why some people are more likely to experience ...
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A team of researchers with members from Oxford University in the U.K., the National Institutes of Health in the U.S. and Leiden University Medical Center in the Netherlands has developed a new approach to battling malaria—boosting ...
Scientists have found a way to boost the efficacy of the world's most powerful antimalarial drug with the help of chemotherapy medicines, according to new research published in the journal Nature Communications.
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An insulin-binding protein in fruit flies could provide new opportunities for tackling disease-carrying mosquitoes, such as malaria and yellow fever, scientists at the University of York have found.
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Deworming has become a common practise across the world. It has proved very successful reducing the burden of parasitic worms among children by more than 50%.
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Recent advances in kidney research have yielded dramatic headlines touting scientists' ability to grow kidneys in the lab. But some experts worry that hype about tissue engineering is excessively raising patients' hopes.
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Here is a list of the winners of the Nobel Medicine Prize in the past 10 years, after James Allison of the US and Tasuku Honjo of Japan were awarded Monday for research that has revolutionised cancer treatment:
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Tuberculosis (TB) is the leading infectious cause of death worldwide, killing roughly 1.6 million people in 2017. In the past 200 years, TB claimed the lives of more than one billion people—more deaths than from malaria, ...
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Japanese scientists have revealed a biological "switch" that influences whether an immature blood cell would develop into a red blood cell or a subtype of white blood cell called myeloid cells in response to infection or ...
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Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases progressing to coma or death. It is widespread in tropical and subtropical regions, including much of Sub-Saharan Africa, Asia, and the Americas.
Five species of Plasmodium can infect and be transmitted by humans. Severe disease is largely caused by Plasmodium falciparum while the disease caused by Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae is generally a milder disease that is rarely fatal. Plasmodium knowlesi is a zoonosis that causes malaria in macaques but can also infect humans.
Malaria transmission can be reduced by preventing mosquito bites by distribution of mosquito nets and insect repellents, or by mosquito-control measures such as spraying insecticides and draining standing water (where mosquitoes breed). Despite a clear need, no vaccine offering a high level of protection currently exists. Efforts to develop one are ongoing. A number of medications are also available to prevent malaria in travelers to malaria-endemic countries (prophylaxis).
A variety of antimalarial medications are available. Severe malaria is treated with intravenous or intramuscular quinine or, since the mid-2000s, the artemisinin derivative artesunate, which is superior to quinine in both children and adults. Resistance has developed to several antimalarial drugs, most notably chloroquine.
There were an estimated 225 million cases of malaria worldwide in 2009. An estimated 655,000 people died from malaria in 2010, a 5% decrease from the 781,000 who died in 2009 according to the World Health Organization's 2011 World Malaria Report, accounting for 2.23% of deaths worldwide. Ninety percent of malaria-related deaths occur in sub-Saharan Africa, with ~60% of deaths being young children under the age of five. Plasmodium falciparum, the most severe form of malaria, is responsible for the vast majority of deaths associated with the disease. Malaria is commonly associated with poverty, and can indeed be a cause of poverty and a major hindrance to economic development.
This text uses material from Wikipedia licensed under CC BY-SA
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