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Alzheimer's disease & dementia news

Medical research

Brain cell membranes' lipids may play big role in Alzheimer's progression

Alzheimer's disease is predominant in elderly people, but the way age-related changes to lipid composition affect the regulation of biological processes is still not well understood. Links between lipid imbalance and disease ...

Neuroscience

New treatment stops progression of Alzheimer's disease in monkey brains

A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer's disease, a new study shows.

Alzheimer's disease & dementia

A new model of Alzheimer's progression

Alzheimer's disease is the most common form of dementia and is characterized by neurodegeneration in regions of the brain involved in memory and learning. Amyloid beta and tau are two toxic proteins that build up in disease ...

Alzheimer's disease & dementia

Good news, bad news from Alzheimer's vaccine trial

An experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to save brain function.

Alzheimer's disease & dementia

A potential new treatment target for Alzheimer's disease

Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.

Medications

Three FDA advisers quit over agency approval of aduhelm

Three members of a U.S. Food and Drug Administration advisory committee have resigned after the agency this week approved a new drug for Alzheimer disease despite a lack of strong proof that it provides any benefits to patients.

Alzheimer's disease & dementia

What happens in brain cells affected by Alzheimer's disease?

Affecting over 50 million people, Alzheimer's disease is the most common form of dementia and primarily occurs in people over the age of 65. The pathology of the disease in the brain is mainly characterized by two factors: ...