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Alzheimer's disease & dementia news
Alzheimer's disease & dementia
Researchers move a step closer to developing at-home test to detect dementia
Tasmanian scientists are a step closer to developing a computer test that can detect dementia, decades before any memory symptoms emerge, recent research has found.
7 hours ago
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Medications
European medicines watchdog rejects new Alzheimer's drug
Europe's medicines watchdog on Friday rejected a marketing request for a new Alzheimer's disease treatment, saying the risks of the medicine's side effects, including potential brain bleeding, outweighed the benefits.
8 hours ago
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Nasal spray clears proteins linked to Alzheimer's, study finds
Scientists in America have developed a nasal spray that can remove proteins in the brain associated with Alzheimer's disease—at least, in mice.
8 hours ago
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New shingles vaccine could reduce risk of dementia
A study of more than 200,000 people by researchers at the University of Oxford found at least a 17% reduction in dementia diagnoses in the six years after the new recombinant shingles vaccination, equating to 164 or more ...
Jul 25, 2024
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Cell aging discovery could help detect early warning signs for neurodegenerative diseases
A team from King's College London and collaborators have pinpointed how different areas of the neuron age differently, with a potential knock-on effect on healthy cell function and the development of neurodegenerative conditions. ...
Jul 25, 2024
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Large study shows early-onset dementia more common than previously reported
A new major study by the University of Eastern Finland, the University of Oulu and Neurocenter Finland explored early-onset dementia in the working-age population in Finland. The study cohort was one of the largest in the ...
Jul 25, 2024
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Exploring the interaction between microglial dysfunction and mitochondrial impairment in Alzheimer's disease
Alzheimer's disease (AD) is marked by severe neurodegeneration and cognitive decline, presenting significant challenges for its prevention and treatment. Traditional hypotheses have focused on amyloid-beta plaques and Tau ...
Jul 25, 2024
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Scientists are closing in on a mouse model for late-onset Alzheimer's disease
Mice don't get Alzheimer's—and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments. Now, researchers at The Jackson Laboratory are working ...
Jul 24, 2024
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Study across multiple brain regions discerns Alzheimer's vulnerability and resilience factors
An MIT study published in Nature provides new evidence for how specific cells and circuits become vulnerable in Alzheimer's disease, and hones in on other factors that may help some people show resilience to cognitive decline, ...
Jul 24, 2024
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Body composition can affect risk of dementia or Parkinson's, research suggests
People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to a study published in ...
Jul 24, 2024
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Unique neutrophil type associated with Alzheimer's disease identified
Researchers have identified a unique type of neutrophil significantly associated with Alzheimer's disease (AD) pathology and mapped the transcriptome of neutrophils in the peripheral blood of AD mice. The study was published ...
Jul 24, 2024
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Study shows traffic-related ultrafine particles hinder mitochondrial functions in olfactory mucosa
Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows. Led by the University of Eastern Finland, the research showed ...
Jul 24, 2024
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New analysis offers most comprehensive roadmap to date for more targeted Alzheimer's research, drug discovery
From studying the human genome to analyzing the way proteins are encoded, or monitoring RNA expression, researchers are rapidly gaining a far richer understanding of the complex genetic and cellular mechanisms that underpin ...
Jul 24, 2024
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Study suggests unresolved anxiety may increase the risk of developing dementia
In a study published in the Journal of the American Geriatrics Society, both chronic and new anxiety were associated with an increased risk of dementia. However, where anxiety had resolved, there was no association with dementia ...
Jul 24, 2024
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Six ways to look after your brain health in your 20s and 30s
Dementia is not an inevitable consequence of aging. It's thought that around 40% of dementia cases could be prevented (or at least delayed) by changing certain lifestyle habits.
Jul 24, 2024
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Alzheimer's disease: Study suggests targeting oligodendrocytes could help reduce amyloid beta production
Oligodendrocytes are an important source of amyloid beta (Aβ) and play a key role in promoting neuronal dysfunction in Alzheimer's disease (AD), according to a study published July 23, 2024 in the open-access journal PLOS ...
Jul 23, 2024
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Data from largest Phase III trial of pre-symptomatic Alzheimer's disease now shared with scientists around the world
Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer's disease, is now widely available to researchers studying the condition. The ...
Jul 23, 2024
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Study identifies new biomarkers of Alzheimer's disease
Recent advances in the study of proteomes (i.e., the entire range of proteins expressed by human cells and tissues) have opened new opportunities for identifying the biological markers of specific diseases or mental disorders. ...
Quit Googling and take naps to cut dementia risk, says AI expert
People can reduce their risk of age-related dementia by exercising their brains properly instead of Googling, according to a leading Canadian academic.
Jul 22, 2024
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Scientists define new type of memory loss in older adults
Researchers at Mayo Clinic have established new criteria for a memory-loss syndrome in older adults that specifically impacts the brain's limbic system. It can often be mistaken for Alzheimer's disease. The good news: Limbic-predominant ...
Jul 17, 2024
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