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Alzheimer's disease & dementia news
Alzheimer's disease & dementia
Network-based analyses uncover how neuroinflammation-causing microglia in Alzheimer's disease form
Cleveland Clinic Genome Center researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study, published in the journal Alzheimer's ...
Dec 6, 2024
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Cardiology
Living in a disadvantaged neighborhood linked to higher blood pressure and lower cognition
New research from Wake Forest University School of Medicine suggests that living in a disadvantaged neighborhood is associated with higher blood pressure and lower cognitive scores, even among people who do not have an existing ...
Dec 6, 2024
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Stroke survivors face much higher odds for dementia, research finds
Stroke survivors have an 80% increased risk of dementia compared to people who've never suffered a stroke, a new study finds.
Dec 6, 2024
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Women with ovarian removal have unique risk and resilience factors for Alzheimer disease, research finds
Research published by a team of researchers from the University of Toronto in collaboration with colleagues from the University of Alberta has found that women who have had both ovaries surgically removed before the age of ...
Dec 5, 2024
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Study reveals lasting effects of common herbicide on brain health
The human brain is an incredibly adaptable organ, often able to heal itself even from significant trauma. Yet for the first time, new research shows even brief contact with a common herbicide can cause lasting damage to the ...
Dec 4, 2024
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Sex differences in neuron protection could reveal Alzheimer's target
Inhibiting TLR7, an immune signaling protein, may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer's disease and ordinary aging, suggests a study led by researchers at Weill Cornell ...
Dec 4, 2024
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Novel all-in-one computational pipeline offers insights into Alzheimer's mechanisms and potential drug targets
Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including Alzheimer's disease (AD). ...
Dec 4, 2024
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New study shows how dementia affects the brain's ability to empathize
Patients with frontotemporal dementia often lack the ability to empathize. A study at Karolinska Institutet has now shown that these patients do not show the same brain activity as healthy individuals when they witness the ...
Dec 3, 2024
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Understanding the genetic roots of rare mutations in Alzheimer's disease
Alzheimer's disease is a debilitating condition that slowly robs people of their memory and cognitive abilities, affecting millions of people worldwide. Familial Alzheimer's disease (FAD), a rare inherited form of the disease, ...
Dec 3, 2024
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Spider brain study leads team to new discovery in Alzheimer's-affected human brains
Researchers from Saint Michael's College and the University of Vermont have made a new discovery that provides a better understanding of how Alzheimer's disease develops in the human brain.
Dec 3, 2024
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Report: Early detection of cognitive impairment spurs people to prepare for future loss of independence
The risk of developing dementia later in life is strongly predicted by a person's cognitive ability, functional limitations and physical health as many as 20 years before onset of the illness, according to a new RAND report.
Dec 3, 2024
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Ketone esters help clear misfolded proteins in mouse model of aging and Alzheimer's disease
Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular processes and aging mechanisms beyond energy production. Research at the Buck Institute shows that ketone bodies can best ...
Dec 2, 2024
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Hidden fat may predict Alzheimer's 20 years ahead of symptoms
Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a study being ...
Dec 2, 2024
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Experts call for responsible messaging on hearing loss and dementia
The U.K.'s leading hearing loss organizations have joined forces to highlight misleading reports by some health professionals and the media that hearing loss causes dementia, and treating hearing loss will reduce our individual ...
Nov 29, 2024
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Alzheimer's disease: Toxic protein is turned bad by immune enzyme, mouse study shows
Alzheimer's disease is one of the world's biggest health problems. Yet, despite the fact millions of people globally are diagnosed with the disease each year, it remains a challenge to treat. This is largely because the underlying ...
Nov 28, 2024
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Disruption of mechanical signaling in brain could be basis for development of Alzheimer's disease, study proposes
A new study from the University of Liverpool represents a significant step forward in scientists' understanding of Alzheimer's disease. Researchers have shed new light on how mechanical signaling in the brain is disrupted ...
Nov 27, 2024
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'Alzheimer's in dish' model shows promise for accelerating drug discovery
A decade ago, researchers introduced a new model for studying Alzheimer's disease. Known as "Alzheimer's in a dish," the model uses cultures of mature brain cells suspended in a gel to recapitulate what takes place in the ...
Nov 27, 2024
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Holiday travel with a loved one with dementia: An expert offers tips
Thanksgiving travel is a must for millions of Americans, but those plans will be complicated for some because they're traveling with a loved one who has Alzheimer's disease or dementia.
Nov 27, 2024
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Machine learning reveals behaviors linked with early Alzheimer's, points to new treatments
Subtle signs of Alzheimer's disease can emerge decades before a diagnosis—often in the form of irregular behaviors that reflect very early stages of brain dysfunction. But until now, identifying and measuring these slight ...
Nov 26, 2024
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Quantifying disease impact and overcoming practical treatment barriers for primary progressive aphasia
Imagine gradually losing the ability to express yourself—not because you've forgotten the words, but because they simply won't come out. This is the reality for individuals living with primary progressive aphasia (PPA), ...
Nov 26, 2024
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Primary care settings face barriers to screening for early detection of cognitive impairment
Early detection of cognitive impairment is essential for improving patient outcomes, but primary care settings face significant challenges in screening. This special report summarizes key points and gaps in knowledge about ...
Nov 26, 2024
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Nasal spray drug shows promise in Alzheimer's research
A future treatment for Alzheimer disease may involve a nasal spray. Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase ...
Nov 25, 2024
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Research links wildfire smoke exposure with increased dementia risk
As Baby Boomers hit retirement, about 1 in 6 Americans is now over the age of 65. The number of Americans living with dementia is projected to skyrocket—but the proportion of older Americans who develop dementia has actually ...
Nov 25, 2024
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Brain shrinkage associated with Alzheimer's immunotherapies may show effectiveness rather than harm
A loss of brain volume associated with new immunotherapies for Alzheimer's disease may be caused by the removal of amyloid plaques, rather than the loss of neurons or brain tissue, finds a study led by UCL researchers.
Nov 25, 2024
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Alzheimer's research presents new strategy for amyloid diagnostics
The first drugs against Alzheimer's disease that are intended to slow down the progression of the condition will soon be authorized in Germany. On November 14, 2024, the EMA granted approval for Lecanemab in the European ...
Nov 25, 2024
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