Detailed mapping shows how astrocytes change throughout the progression of Alzheimer's disease
Astrocytes are star-shaped glial cells in the central nervous system that support neuronal function, maintain the blood-brain barrier, and contribute to brain repair and homeostasis. The evolution of these cells throughout ...
Portable MRI shows promise for expanding brain imaging for Alzheimer's disease
Globally, approximately 139 million people are expected to have Alzheimer's disease (AD) by 2050. Magnetic resonance imaging (MRI) is an important tool for identifying changes in brain structure that precede cognitive decline ...
Dec 10, 2024
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Does menopause hormone therapy increase or decrease your risk of dementia? Here's the science
By 2050, around 135 million people worldwide will be living with dementia. The most common cause of dementia is Alzheimer's disease. Women are more likely than men to develop Alzheimer's disease, even after accounting for ...
Dec 10, 2024
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New study highlights how musical interactions can support relationships for people living with dementia
More than 982,000 individuals in the U.K. are currently living with dementia, a condition that gradually erodes cognitive functions and can significantly impact daily life.
Dec 10, 2024
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Novel mechanism in brain blood flow regulation offers insights into treating stroke and dementia
A team of UVM scientists led by Mark Nelson, Ph.D., from the Larner College of Medicine at the University of Vermont, has uncovered a novel mechanism that reshapes our understanding of how blood flow is regulated in the brain. ...
Dec 9, 2024
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Brain tissue study offers new genetic insights into Alzheimer's disease complexity
A study by the team of Prof. Kristel Sleegers (VIB-UAntwerp), published in Acta Neuropathologica, has offered new insights into the genetic factors that drive Alzheimer's disease. Using samples from the Leuven Brain Collection, ...
Dec 9, 2024
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Study finds no evidence high dementia risk among former professional soccer players is driven by lifestyle factors
A new study has found no evidence that common modifiable health and lifestyle risk factors are responsible for the elevated dementia risk observed among former professional soccer players.
Dec 9, 2024
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UK study reveals disappointing results for the effectiveness of online dementia caregiver resource
A major UK study into the effectiveness of a World Health Organization's (WHO) online resource for caregivers of people living with dementia has revealed disappointing results.
Dec 9, 2024
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Network-based analyses uncover how neuroinflammation-causing microglia in Alzheimer's disease form
Cleveland Clinic Genome Center researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study, published in the journal Alzheimer's ...
Dec 6, 2024
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Living in a disadvantaged neighborhood linked to higher blood pressure and lower cognition
New research from Wake Forest University School of Medicine suggests that living in a disadvantaged neighborhood is associated with higher blood pressure and lower cognitive scores, even among people who do not have an existing ...
Dec 6, 2024
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Stroke survivors face much higher odds for dementia, research finds
Stroke survivors have an 80% increased risk of dementia compared to people who've never suffered a stroke, a new study finds.
Dec 6, 2024
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Women with ovarian removal have unique risk and resilience factors for Alzheimer disease, research finds
Research published by a team of researchers from the University of Toronto in collaboration with colleagues from the University of Alberta has found that women who have had both ovaries surgically removed before the age of ...
Dec 5, 2024
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Study reveals lasting effects of common herbicide on brain health
The human brain is an incredibly adaptable organ, often able to heal itself even from significant trauma. Yet for the first time, new research shows even brief contact with a common herbicide can cause lasting damage to the ...
Dec 4, 2024
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Sex differences in neuron protection could reveal Alzheimer's target
Inhibiting TLR7, an immune signaling protein, may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer's disease and ordinary aging, suggests a study led by researchers at Weill Cornell ...
Dec 4, 2024
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Novel all-in-one computational pipeline offers insights into Alzheimer's mechanisms and potential drug targets
Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including Alzheimer's disease (AD). ...
Dec 4, 2024
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New study shows how dementia affects the brain's ability to empathize
Patients with frontotemporal dementia often lack the ability to empathize. A study at Karolinska Institutet has now shown that these patients do not show the same brain activity as healthy individuals when they witness the ...
Dec 3, 2024
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Understanding the genetic roots of rare mutations in Alzheimer's disease
Alzheimer's disease is a debilitating condition that slowly robs people of their memory and cognitive abilities, affecting millions of people worldwide. Familial Alzheimer's disease (FAD), a rare inherited form of the disease, ...
Dec 3, 2024
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Spider brain study leads team to new discovery in Alzheimer's-affected human brains
Researchers from Saint Michael's College and the University of Vermont have made a new discovery that provides a better understanding of how Alzheimer's disease develops in the human brain.
Dec 3, 2024
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Report: Early detection of cognitive impairment spurs people to prepare for future loss of independence
The risk of developing dementia later in life is strongly predicted by a person's cognitive ability, functional limitations and physical health as many as 20 years before onset of the illness, according to a new RAND report.
Dec 3, 2024
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Ketone esters help clear misfolded proteins in mouse model of aging and Alzheimer's disease
Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular processes and aging mechanisms beyond energy production. Research at the Buck Institute shows that ketone bodies can best ...
Dec 2, 2024
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Hidden fat may predict Alzheimer's 20 years ahead of symptoms
Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a study being ...
Dec 2, 2024
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Experts call for responsible messaging on hearing loss and dementia
The U.K.'s leading hearing loss organizations have joined forces to highlight misleading reports by some health professionals and the media that hearing loss causes dementia, and treating hearing loss will reduce our individual ...
Nov 29, 2024
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Alzheimer's disease: Toxic protein is turned bad by immune enzyme, mouse study shows
Alzheimer's disease is one of the world's biggest health problems. Yet, despite the fact millions of people globally are diagnosed with the disease each year, it remains a challenge to treat. This is largely because the underlying ...
Nov 28, 2024
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