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Alzheimer's disease & dementia news
Neuroscience
A chance observation finds potential hearing biomarker for Alzheimer's disease
Science lends itself to questions, changing hypotheses, and chance findings. Recently, in the White Lab at the Del Monte Institute for Neuroscience at the University of Rochester, Neuroscience graduate student Daxiang Na ...
13 hours ago
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Alzheimer's disease & dementia
Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes
Currently there are no objective, easily assessed diagnostic markers for Alzheimer's disease, and no good therapeutic options. Taking an agnostic approach, proteomics expert Hanno Steen, Ph.D., and neurobiologist Judith Steen, ...
16 hours ago
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Researchers apply artificial intelligence for early risk forecasting of Alzheimer's disease
An international research team led by the Hong Kong University of Science and Technology (HKUST) has developed an artificial intelligence (AI)-based model that uses genetic information to predict an individual's risk of developing ...
16 hours ago
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Research group calls for consensus, collaboration to improve understanding of how infections drive Alzheimer's
A research consortium, including a Philadelphia College of Osteopathic Medicine neuroscientist and his research coordinator, are calling for a consensus on how scientists identify and evaluate how infections contribute to ...
8 hours ago
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Q&A: Start of new era for Alzheimer's treatment
Researchers say we appear to be at the start of a new era for Alzheimer's treatment. Trial results published in January showed that for the first time a drug has been able to slow the cognitive decline characteristic of the ...
9 hours ago
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Nursing home dementia residents' care linked to majority presence, new study finds
The quality of care for nursing home residents with Alzheimer's disease and related dementias is best when they are in the majority, but most facilities also accommodate a heterogeneous population, where specialized staff ...
Jun 6, 2023
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Reducing dementia risks
Former first lady Rosalynn Carter has been diagnosed with dementia. A family statement, posted on The Carter Center website, says that she continues to live happily at home with her husband, enjoying spring in Plains, Georgia, ...
Jun 6, 2023
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Healthy vascular fat during menopause may stave off dementia later in life
A new study published in Alzheimer's & Dementia is further evidence that the menopause transition is a particularly important time for women and their doctors to pay attention to heart health, in turn protecting their brain ...
Jun 5, 2023
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One barrier to Alzheimer's diagnoses could crumble with discovery of a blood biomarker
"My mother has always been my hero," Mario Browne told a crowd of 180 people on Thursday.
Jun 5, 2023
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Poorly insulated nerve cells shown to promote Alzheimer's disease in old age
Alzheimer's disease, an irreversible form of dementia, is considered the world's most common neurodegenerative disease. The prime risk factor for Alzheimer's is age, although it remains unclear why. It is known that the insulating ...
Jun 2, 2023
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Single-cell dissection of Alzheimer's vascular changes across six brain regions
Your brain is powered by 400 miles of blood vessels that provide nutrients, clear out waste products, and form a tight protective barrier—the blood brain barrier—that controls which molecules can enter or exit. However, ...
Jun 2, 2023
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Alzheimer's disease plasma biomarker contributes to postoperative delirium-like behavior in rodents
Tauopathy is one of the hallmarks of Alzheimer's disease (AD) pathogenesis, and the phosphorylation of Tau at threonine 217 (Tau-PT217) and 181 (Tau-PT181) represents new plasma biomarkers capable of detecting early-stages ...
Jun 2, 2023
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Medicare will cover new class of Alzheimer's drugs if fully approved by FDA, with limits
Medicare will soon cover a new class of Alzheimer's drugs if they receive full approval from the U.S. Food and Drug Administration, with some key limits.
Jun 2, 2023
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Being socially active in mid-late life linked to 30–50% lower dementia risk
People who are socially engaged when middle aged and beyond are 30-50% less likely to develop dementia later on, finds a new review of evidence led by UCL researchers.
Jun 1, 2023
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Researchers identify several new genetic risk factors for Alzheimer's disease unique to Ashkenazi Jews
Alzheimer's disease (AD), the most common neurodegenerative disorder in the world, affects individuals of all races and ethnicities; however, most genetic research for AD has been performed on individuals of European ancestry ...
Jun 1, 2023
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Study: Stress granules control Alzheimer's gene transcripts and neuronal proteostasis
A new research paper was published on the cover of Aging, title "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."
Jun 1, 2023
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Tire wear and higher temperatures found to accelerate neurodegeneration in C. elegans models
Scientists at the IUF—Leibniz Research Institute for Environmental Medicine in Düsseldorf, Germany, have shown that tire wear, age and temperature accelerate neurodegeneration (i.e. the decline of nerve cells) in models ...
Jun 1, 2023
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Sleep deprivation is a risk factor for Alzheimer's, say scientists who turned to animal models to find out why
Scientists have long explored the link between disturbances in sleep patterns and neurodegenerative diseases. Powerful evidence has emerged in recent years linking disrupted sleep to Parkinson's, and a massive body of research ...
Tracking early signs of Alzheimer's pathology in a mouse model
About two-thirds of the risk for Alzheimer's disease (AD) is thought to arise from genetic influences, but about a third could be influenced by environment and lifestyle, opening the door for behavioral interventions that ...
May 31, 2023
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Ischemic heart disease linked to increased risk of dementia and faster cognitive decline in older people
Older people with ischemic heart disease have an increased long-term risk of dementia and accelerated cognitive decline, independent of coexisting atrial fibrillation, heart failure, and cerebrovascular disease. A recent ...
May 31, 2023
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