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Alzheimer's disease & dementia news
Medications
Deferiprone accelerates cognitive decline in Alzheimer's trial
A multi-institutional study made up of 26 researchers led by the University of Melbourne has discovered that iron-reducing deferiprone accelerates cognitive decline in patients with early Alzheimer's disease. This unexpected ...
Nov 11, 2024
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Neuroscience
TYK2 enzyme alters tau protein that contributes to Alzheimer's disease, researchers discover
Researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital and collaborating institutions discovered that the enzyme TYK2 transforms the normal ...
Nov 11, 2024
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Most effective way to communicate with Alzheimer's patients identified
Research involving the UAB reveals the most effective way to talk to people with Alzheimer's so that their emotional response and their levels of attention and understanding are the highest possible.
Nov 11, 2024
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Study highlights challenges of reducing risky drugs in Alzheimer's patients
Can large national health plans make an impact in reducing prescribing of high-risk medications to people with Alzheimer's disease or related dementias by mailing patients, caregivers and their health care providers educational ...
Nov 8, 2024
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Nasal spray made from stem cell-derived vesicles could treat Alzheimer's disease
A new therapy may delay Alzheimer's disease progression by years, according to a study by researchers at Texas A&M University College of Medicine. Published in the Journal of Extracellular Vesicles, the research aims to explore ...
Nov 7, 2024
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Unrecognized cognitive impairment in vulnerable older adults is ubiquitous, says study
One of the first studies to investigate the prevalence of unrecognized cognitive impairment among patients seen at Federally Qualified Health Centers, has found that it is ubiquitous, especially among minoritized older adults. ...
Nov 7, 2024
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Mouse model demonstrates Chinese herbal medicine's potential in preventing dementia
Attempts to discover a breakthrough dementia drug might be drawing attention these days, but traditional medicinal products can offer hints for preventive medicine.
Nov 6, 2024
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Alzheimer's and alcohol use disorder found to share similar gene expression patterns
Nearly 7 million Americans have Alzheimer's disease, and this number is predicted to double by 2060. While aging and genetic predisposition are the most important risk factors for Alzheimer's, epidemiological studies suggest ...
Nov 5, 2024
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AI-based dementia prediction technology uses automatic speech recognition
Researchers in South Korea have developed an AI-based technology that can analyze the voice/speech of the elderly to screen and detect those who are at high risk of mild cognitive impairment and dementia.
Nov 5, 2024
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New criteria to avoid the over-diagnosis of Alzheimer's disease
Diagnosis of Alzheimer's disease (AD) is currently largely based on the presence of biomarkers. This may lead to a problematic over-diagnosis if this is incorrectly interpreted. To counter this problem, a global expert panel ...
Nov 5, 2024
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Brain immune cells amplify damage caused by Alzheimer's risk gene, study finds
In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein—the most important genetic risk factor for Alzheimer's disease—the ...
Nov 4, 2024
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Study shows how education, occupation and wealth affect the risk of cognitive impairment
Socioeconomic factors such as education, occupation, and wealth influence the likelihood of developing cognitive impairment or dementia in later life and whether a person is likely to recover, finds a new study led by UCL ...
Nov 1, 2024
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Glaucoma drug shows promise against neurodegenerative diseases, animal studies suggest
A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of the protein tau, which causes various forms of dementia and is implicated in Alzheimer's disease.
Oct 31, 2024
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Fibrils study fills in a missing piece for neurodegenerative disease research
Research led by the University of Michigan has provided compelling evidence that could solve a fundamental mystery in the makeup of fibrils that play a role in Alzheimer's, Parkinson's and other neurodegenerative diseases.
Oct 31, 2024
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Q&A: Designing a backup for a drug compound to improve memory loss in people with Alzheimer's disease
Cognitive dysfunctions are common symptoms for Alzheimer's disease, schizophrenia, and other disorders of the central nervous system. Most people are familiar with the memory problems as one type of dysfunction, but cognitive ...
Oct 31, 2024
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Specific inhibitors protect nerve cells from dying in mouse models for Alzheimer's
Alzheimer's disease, the leading cause of dementia, affects over 55 million people worldwide. The disease is characterized by the buildup of amyloid-beta plaques and tau protein tangles in the brain, which disrupt cell communication ...
Oct 30, 2024
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New study shows combination therapy slows cognitive decline in at-risk populations
An new study led by the Center for Addiction and Mental Health (CAMH), and with partnership across several Toronto Dementia Research Alliance (TDRA) sites—Baycrest, Sunnybrook Health Science Center, Unity Health Toronto, ...
Oct 30, 2024
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Taking five or more medications daily can negatively impact older adults with Alzheimer's disease or related dementias
Polypharmacy, commonly defined as taking five or more medications daily, is a significant health care concern impacting over 30% of older adults. It is associated with poor health outcomes like falls, medication interactions, ...
Oct 30, 2024
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Expansion of Medicare to cover in-home care would help millions of families stretched thin by Alzheimer's, expert says
Vice President Kamala Harris' proposal to expand Medicare to cover the costs of long-term care at home, plus vision and hearing benefits for seniors, made only a modest splash in the news. But it caught the attention of USC's ...
Oct 30, 2024
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Data suggest ED visit rate 36.1 per 1,000 older adults with Alzheimer's disease
For adults aged 65 years and older with Alzheimer's disease, the emergency department visit rate was 36.1 visits per 1,000 adults in 2020 to 2022, according to an October data brief published by the National Center for Health ...
Oct 30, 2024
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Physical activity of any intensity linked to lower risk of death after dementia diagnosis
Physical activity of any intensity after a diagnosis of dementia is associated with around a 30% lower risk of death, finds research published online in the British Journal of Sports Medicine.
Oct 29, 2024
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Alzheimer's drug approved in the UK, but it won't be available on the NHS—here's why
The UK's drugs regulator—the MHRA—has approved the Alzheimer's drug donanemab, but it won't be available on the NHS.
Oct 29, 2024
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Alzheimer's research: Superspreader fibrils caught in the act
The treatment of dementia disorders such as Alzheimer's is still one of the greatest challenges facing modern medicine. In the course of neurodegenerative diseases, certain proteins such as the amyloid β protein accumulate ...
Oct 28, 2024
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Halloween can be extra scary for folks with dementia: Expert offers caregiver tips
Halloween is meant to be a spooky season, but it can be downright terrifying to someone suffering from Alzheimer's disease or dementia.
Oct 28, 2024
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New insights into amyloid β fibril growth offer hope for halting Alzheimer's progression
A collaborative research group has uncovered a new mechanism in the growth of amyloid β (Aβ) fibrils, which are closely associated with Alzheimer's disease. Using advanced high-speed atomic force microscopy (HS-AFM), the ...
Oct 24, 2024
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