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Alzheimer's disease & dementia news
Genetics
Gene editing tool reduces Alzheimer's plaque precursor in mice
A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers ...
Dec 23, 2024
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Neuroscience
Alzheimer's progression tied to stress-induced microglial lipid release
Researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD).
Dec 23, 2024
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New clinical practice guideline on process for diagnosing Alzheimer's disease or related form of cognitive impairment
We have entered a new era of improved and emerging biologically-based diagnostic biomarkers for Alzheimer's disease (AD) and AD-related neurodegenerative disorders (ADRD) that are rapidly impacting evaluation and care paradigms ...
Dec 23, 2024
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Tips for spending holiday time with family members who live with dementia
The holiday spirit is infectious, even for people suffering from dementia.
Dec 23, 2024
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Study explores association between Tau filaments and extracellular vesicles in Alzheimer's disease
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder associated with a progressive decline in memory and mental abilities, which can significantly hinder people's ability to complete daily tasks. Past studies ...
Using an AI tool, researchers find poor vascular health accelerates brain aging
Using an AI tool, researchers at Karolinska Institutet have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation ...
Dec 20, 2024
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How to boost your brain health
Can simple diet and lifestyle changes keep your brain healthy? Do you have the power to prevent Alzheimer's disease and dementia or lower your MS risks?
Dec 20, 2024
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How and why music can reduce distress in people with dementia: A blueprint for personalized music therapy
A new study has demonstrated for the first time how and why music can reduce distress and agitation for people with advanced dementia.
Dec 19, 2024
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Chronic gut infection could play a role in Alzheimer's development
Arizona State University and Banner Alzheimer's Institute researchers, along with their collaborators, have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's ...
Dec 19, 2024
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Plasma biomarkers offer new clues in Alzheimer's detection
How are emerging plasma biomarkers related to the diagnostic tests currently used in clinical routines? And does the earlier evidence from highly selective research cohorts translate to the heterogeneous real-world data? ...
Dec 19, 2024
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Research suggests coffee may protect against cognitive decline in people with atrial fibrillation
Drinking multiple cups of coffee a day may help prevent cognitive decline in people with atrial fibrillation (AFib or AF), according to new research published in the Journal of the American Heart Association.
Dec 19, 2024
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First successful clinical trial of VU319 brings Alzheimer's treatment one step closer
Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a phase I single ...
Dec 19, 2024
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Blight or benefit: How cellular neighbors shape the aging brain
Much like plants in a thriving forest, certain cells in the brain create a nurturing environment, enhancing the health and resilience of their neighbors, while others promote stress and damage, akin to a noxious weed in an ...
Dec 18, 2024
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Sexism is a risk factor for memory decline among women, study finds
Women born in the most sexist U.S. states experience faster memory decline in later years compared to women born in the least sexist states, a new study by researchers at Columbia University Vagelos College of Physicians ...
Dec 18, 2024
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Good news for seniors: Study finds antibiotics not linked to dementia
For healthy older adults, using antibiotics is not associated with an increased risk of cognitive impairment or dementia, according to a study published in the December 18, 2024, online issue of Neurology.
Dec 18, 2024
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Blood-based biomarker offers hope for early dementia detection
To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate "downstream" biological markers—those at ...
Dec 18, 2024
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Supportive marriages crucial for dementia caregivers' well-being: Study highlights key role of spousal support
A new Rice University study sheds light on the critical role marital relationships play in the mental and physical health of caregivers for spouses living with dementia, revealing that caregiver mental health dramatically ...
Dec 18, 2024
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Inflammatory dietary habits linked to 84% higher risk of dementia
Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases at UT Health San Antonio, Boston University School of Medicine and the Framingham Heart Study have found that higher scores on the Dietary Inflammatory Index ...
Holiday stress can lead Alzheimer's patients and those with dementia to go missing
Holidays are a time for families and friends to gather, but for older people with Alzheimer's disease and other dementias, it can cause so much stress and confusion that they could be in danger of what experts calls wandering.
Dec 17, 2024
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Study finds lower rates of death from Alzheimer's disease among taxi and ambulance drivers
A new study raises the possibility that jobs that require frequent spatial processing—such as figuring out a taxi route or the best way to navigate to a hospital—could lead to lower rates of death from Alzheimer's disease. ...
Dec 16, 2024
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Reading books over watching TV linked to lower dementia risk
It's that time of the year when most of us get the chance to sit back and enjoy some well-deserved down time. But whether you reach for the TV control, or a favorite book, your choice could have implications for your long-term ...
Dec 16, 2024
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New study sheds light on progressive supranuclear palsy
Progressive supranuclear palsy (PSP) is a severe and rapidly progressing neurodegenerative disease that affects both motor and cognitive functions. Often misdiagnosed or underdiagnosed due to a lack of specific biomarkers, ...
Dec 16, 2024
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How to keep life engaging for people with Alzheimer's
Adapting activities for individuals with Alzheimer's disease is essential for maintaining their engagement and well-being. As Alzheimer's progresses, activities that were once routine can become challenging. Here's how caregivers ...
Dec 16, 2024
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Microglia: The double-edged sword in Alzheimer's progression
Microglia are known to play an important role in Alzheimer's disease, but exactly what they do has remained a mystery. Scientists in the Bart De Strooper Lab at the VIB-KU Leuven Center for Brain & Disease have unraveled ...
Dec 13, 2024
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'Dementia doesn't have to be your destiny:' Research highlights influence of lifestyle changes
Many people could greatly improve their odds against developing dementia by making four, low-cost lifestyle changes, Western researchers have discovered.
Dec 12, 2024
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