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Alzheimer's disease & dementia news
Alzheimer's disease & dementia
Geneticists develop world's first bioinformatic tool to identify amyloids consisting of multiple copies of same protein
Scientists from St Petersburg University and the University of Montpellier have developed the first software enabling the prediction of pairs of proteins in amyloid fibrils capable of co-aggregation, i.e. a process by which ...
6 hours ago
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Alzheimer's disease & dementia
Obesity-induced cognitive decline: Role of brain oxidation and tocotrienols
Obesity has become a pressing worldwide health issue, with rates steadily rising over recent decades. Beyond its well-documented associations with physical health issues, such as cardiovascular disease and diabetes, obesity ...
23 hours ago
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Study links lack of diversity in Alzheimer's disease clinical trials to differences in amyloid levels
It's long been recognized that some of the groups most likely to get dementia, including African Americans and Hispanics, are greatly underrepresented in clinical trials. Now a new USC study shows that people from certain ...
Apr 17, 2024
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How Alzheimer's disease progresses faster in people with Down syndrome
Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age. A new study by researchers at Washington University School of Medicine in St. Louis shows that the disease both starts ...
Apr 17, 2024
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Antipsychotics for dementia linked to more harms than previously acknowledged
Antipsychotic use in people with dementia is associated with elevated risks of a wide range of serious adverse outcomes including stroke, blood clots, heart attack, heart failure, fracture, pneumonia, and acute kidney injury, ...
Apr 17, 2024
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Does using your brain more at work help ward off thinking, memory problems?
The harder your brain works at your job, the less likely you may be to have memory and thinking problems later in life, according to a new study published in the journal Neurology. This study does not prove that stimulating ...
Apr 17, 2024
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Scientists identify cell vulnerability 'fingerprint' related to Parkinson's, Lewy body dementia
A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.
Apr 16, 2024
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Common HIV treatments may aid Alzheimer's disease patients
Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need. Scientists ...
Apr 16, 2024
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New mechanism uncovered in early stages of Alzheimer's disease
Alzheimer's disease (AD) remains one of the most challenging and prevalent neurodegenerative disorders, affecting millions of individuals worldwide. In a new study published in Developmental Cell, researchers from the lab ...
Apr 15, 2024
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Researchers say common dementia medication doesn't increase risk of death, life-threatening heart abnormalities
Researchers with McMaster University have found that a commonly prescribed dementia medication doesn't increase the risk of death or certain heart rhythm problems, contrary to past warnings.
Apr 15, 2024
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Local greenery and low crime rates may reduce dementia risk factors
Living in areas with shorter distances to greenspace and lower crime rates are associated with having fewer modifiable dementia risk factors, Monash University-led research has found.
Apr 15, 2024
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A new diagnostic model offers hope for Alzheimer's
A new mathematical model offers hope for better prediction and treatment of Alzheimer's disease. Most mathematical models of Alzheimer's are theoretical, focusing on short term molecular and cellular-level changes that cannot ...
Apr 11, 2024
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Study shows air pollution is associated with increased risk of developing Alzheimer's disease
A new Emory University study has found that adults exposed to high levels of air pollution were at an increased risk of developing Alzheimer's disease.
Apr 11, 2024
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Newly found genetic variant defends against Alzheimer's disease
Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease. The study, "Rare ...
Apr 10, 2024
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Geraniol attenuates oxidative stress and cognitive impairment in mouse aging model
A new research paper titled "Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model" has been published in Aging.
Apr 10, 2024
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Study suggests racial discrimination during midlife associated with Alzheimer's disease pathology later in life
Racial discrimination experienced during midlife is associated with Alzheimer's disease pathology, according to a new study from researchers at Wake Forest University School of Medicine and the University of Georgia.
Apr 10, 2024
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Improving dementia care in nursing homes: Learning from the pandemic years
No one associated with nursing homes—as residents or their families, friends, staff, or administrators—is unaware of the massive impact of the pandemic on these facilities, which provide essential services to a growing ...
Apr 10, 2024
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Brain vesicles found to contain selectively packaged, full-length mRNA
Scientists at Sanford Burnham Prebys have demonstrated that vesicles traveling between cells in the brain carry more complete instructions for altering cellular function than previously thought.
Apr 9, 2024
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Cognitive decline may be detected using network analysis, according to researchers
We all lose our car keys or our glasses from time to time. Most people would be correct to laugh it off as a normal part of aging. But for others, cognitive decline may start as a worrying but clinically unnoticeable step ...
Apr 9, 2024
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Human neuron model paves the way for new Alzheimer's therapies
Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer's disease ...
Apr 5, 2024
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