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Alzheimer's disease & dementia news
Genetics
Master copper regulator discovery may offer Alzheimer's clues
New therapeutic opportunities often emerge from research on simple organisms. For instance, the 2020 Nobel Prize in Chemistry awarded to Emmanuelle Charpentier, Ph.D., and Jennifer Doudna, Ph.D., for their CRISPR-based DNA ...
22 hours ago
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Alzheimer's disease & dementia
Some diabetes drugs tied to lower risk of dementia, Parkinson's disease
A class of drugs for diabetes may be associated with a lower risk of dementia and Parkinson's disease, according to a study published in the September 18, 2024, online issue of Neurology.
18 hours ago
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New research finds higher levels of leptin indicate brain protection against late-life dementia
New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, ...
19 hours ago
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Preparing for widespread use of biomarkers to diagnose Alzheimer's disease
For years, many people with Alzheimer's disease have been diagnosed clinically and confirmed at autopsy. Now Alzheimer's disease pathology can be identified with relatively high accuracy via a blood test that has the potential ...
21 hours ago
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Bridging gaps: Researchers apply cancer insights to advance Alzheimer's therapies
In the ever-evolving field of Alzheimer's disease research, the development of disease-modifying therapies has sparked both excitement and debate. While these therapies represent a promising shift in the treatment landscape, ...
23 hours ago
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Understanding changes in pre-clinical Alzheimer's disease: Study finds two proteins impact brain activity differently
Amyloid-beta and tau proteins have long been associated with Alzheimer's disease. The pathological buildup of these proteins leads to cognitive decline in people with the disease. How it does that, though, remains poorly ...
Sep 18, 2024
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New Alzheimer's studies reveal disease biology, risk for progression and the potential for a novel blood test
The failure to diagnose Alzheimer's disease—the most common form of dementia in the elderly—at an early stage of molecular pathology is considered a major reason that treatments fail in clinical trials. Previous research ...
Sep 18, 2024
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Evidence of inverse relationship between incidence of Alzheimer's disease and colorectal cancer
A team of epidemiologists at the First Hospital of Hebei Medical University, in China, has shown experimental evidence of an inverse relationship between incidences of Alzheimer's disease and colorectal cancer.
Research team finds genetic risk-factor overlap between Alzheimer's disease, and all-cause and vascular dementias
In landmark research, scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have reported the largest-ever genome-wide association study of dementia from all causes, revealing ...
Sep 17, 2024
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Brain vasculature changes important for predicting cognitive impairment
University of Oklahoma researchers have recently published a study showing that several measurements of the brain, including blood flow and the brain's ability to compensate for the lack of it, are better predictors of mild ...
Sep 17, 2024
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The impact of mild cognitive impairment and dementia on social skills
Research using participants from one of Australia's largest and longest running studies of aging has looked at the impact of mild cognitive impairment and dementia on a person's ability to interact in social contexts.
Sep 16, 2024
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New figures indicate substantially higher future need for palliative care among people living with dementia
A new Research Letter published in Palliative Medicine estimates that the palliative care needs of people living with dementia in England and Wales will be much higher by 2040 than previous projections have indicated.
Sep 16, 2024
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New therapy that targets and destroys tau tangles: A promising Alzheimer's disease treatment
Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.
Sep 13, 2024
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A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy
Patients regularly show up at university hospitals with diseases so rare and specific as to be scarcely known to physicians in private practice. Primary 4-repeat tauopathies are a good example. These are diseases which are ...
Sep 12, 2024
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Boosting brain protein levels may slow decline from Alzheimer's
A study published in the journal Brain shows that increases in protein levels with new Alzheimer's drugs can explain the slowing of cognitive impairment at least as well as the reduction in amyloid plaques.
Sep 11, 2024
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Researchers uncover shared cellular mechanisms across three major dementias
Researchers have for the first time identified degeneration-associated "molecular markers"—observable changes in cells and their gene-regulating networks—that are shared by several forms of dementia that affect different ...
Sep 11, 2024
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More diversity needed in dementia studies to enhance targeted therapies
A lack of diversity in genomic studies for dementia could limit the effectiveness of targeted therapies across underrepresented populations, finds research by UCL experts.
Sep 11, 2024
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Games, puzzles and reading can slow cognitive decline in the elderly—even in those with mild cognitive impairment
The aging process can lead to diminished cognitive functioning for older adults. In addition, about 10 percent of people previously diagnosed with mild cognitive impairment develop Alzheimer's disease or other forms of dementia ...
Sep 10, 2024
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Trauma exposure accelerates brain aging which can lead to Alzheimer's disease, study suggests
As the median age of our population rises, so does the number of people diagnosed with Alzheimer's disease. With advances in technology, it's easier to determine brain age and identify blood-based Alzheimer's disease biomarkers. ...
Sep 10, 2024
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Hope for Alzheimer's: Q&A with neurological disease expert
There's no question we've reached a turning point for Alzheimer's disease treatment.
Sep 10, 2024
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Alzheimer's study: Drug combination improves memory skills in mice
Laboratory mice with cognitive issues including Alzheimer's disease showed improved memory skills within a couple of weeks of treatment with a new medicine tested at Colorado State University.
Sep 9, 2024
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1 in 10 people with dementia experience suicidal thoughts, finds study
People with dementia are more likely to have suicidal thoughts but are not necessarily more likely to attempt or die by suicide than the general population, finds a new study led by UCL researchers.
Sep 9, 2024
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Study of older patients suggests 1 in 5 cases of dementia may be attributable to vision impairment
Prior research has found that there may be a connection between hearing loss in aging people and the onset of dementia. In a new study, a team of health care researchers and geriatric specialists affiliated with Johns Hopkins ...
Falling for financial scams? It may signal early Alzheimer's disease
Older adults who are more vulnerable to financial scams may have brain changes linked to a higher risk of Alzheimer's disease, according to a first-of-its-kind study led by researchers at the USC Dornsife College of Letters, ...
Sep 6, 2024
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Alzheimer's study reveals critical differences in memory loss progression based on the presence of specific proteins
A study from Karolinska Institutet, published in the journal Molecular Psychiatry, offers new insights into the progression of Alzheimer's disease (AD). The research reveals critical differences in the progression of memory ...
Sep 6, 2024
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