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Alzheimer's disease & dementia news
Cardiology
AFib diagnosed in midlife linked to 21% increased risk of dementia at any age, 36% higher risk of early-onset dementia
New research presented at the EHRA 2025, a scientific congress of the European Society of Cardiology, shows that the presence of atrial fibrillation (AFib) increases the risk of future dementia by 21% in patients diagnosed ...
15 hours ago
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Neuroscience
Protein 'seeds' trigger key pathological features of ALS and frontotemporal dementia
Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a study published in Neuron, researchers report 'seeding' this accumulation through fragments of the culprit protein created ...
Mar 28, 2025
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Neurons use simple physics to maintain their connections, but these processes change in Alzheimer's patients
Scientists at Auburn University have uncovered a fundamental principle of how brain cells stay connected, and their discovery could change how we understand Alzheimer's disease. Published in Cell Reports, this study reveals ...
Mar 27, 2025
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Common drug combinations affect Alzheimer's Disease pathology differently in male and female mice
Certain widely used drug combinations may either slow down or worsen the progression of Alzheimer's disease, but their effects differ between sexes. A new study from Karolinska Institutet, published in Alzheimer's & Dementia, ...
Mar 27, 2025
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Digital technology and AI can support workers with dementia: New research
People with dementia can enjoy productive and rewarding working lives in the digital era, contrary to the widespread stereotype that dementia is incompatible with the use of modern technology, according to new research from ...
Mar 27, 2025
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What is vascular dementia? A neurologist explains
An estimated 55 million people are believed to be living with dementia, according to health officials. Vascular diseases contribute to approximately 25% of all diagnoses.
Mar 27, 2025
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How cholesterol regulation may affect Alzheimer's development
Alzheimer's Disease (AD) is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like sleep changes, anxiety, and depression can be early signs of the disease. These symptoms of underlying ...
Mar 26, 2025
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Highly educated people face steeper mental declines after stroke, study finds
When someone has a stroke, it can accelerate the loss of cognitive ability over the coming years. Stroke survivors who have attended some level of higher education may face even steeper mental declines, according to a study ...
Mar 26, 2025
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Neighborhood status may affect risk of dementia, study suggests
People living in more disadvantaged neighborhoods may be more likely to develop dementia than people living in neighborhoods with fewer disadvantages, according to a study published online in Neurology. The study does not ...
Mar 26, 2025
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Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments
A new open-source model of brain metabolism—the most complex ever generated—has shown how altering key chemicals could restore aged cells to their youthful activity and resilience.
Mar 25, 2025
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ADHD may be associated with an increased risk of dementia
An adult brain affected by attention deficit disorder with or without hyperactivity (ADHD) presents modifications similar to those observed in individuals suffering from dementia.
Mar 25, 2025
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Study confirms accuracy of blood test for early Alzheimer's detection in Asian populations
A study in Alzheimer's & Dementia has demonstrated the high accuracy of plasma p-tau217 as a blood-based biomarker for detecting abnormal brain beta-amyloid (Aβ) pathology, a hallmark of Alzheimer's disease (AD).
Mar 25, 2025
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Long-term gantenerumab Alzheimer's trial halted due to 'no regulatory path'
Washington University School of Medicine led a study evaluating long-term gantenerumab treatment in individuals with dominantly inherited Alzheimer's disease (DIAD). Gantenerumab was associated with serious safety concerns, ...
An at-home smell test could pave the way for early detection of Alzheimer's disease
When it comes to early detection of cognitive impairment, a new study suggests that the nose knows. Researchers from Mass General Brigham have developed olfactory tests—in which participants sniff odor labels that have ...
Mar 24, 2025
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An at-home smell test could pave the way for early detection of Alzheimer's disease
When it comes to early detection of cognitive impairment, a new study suggests that the nose knows. Researchers from Mass General Brigham have developed olfactory tests—in which participants sniff odor labels that have ...
Mar 24, 2025
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Renewal processes in the cell: Disruptions favor diseases such as Alzheimer's and Parkinson's, study finds
In an international research collaboration involving the University Medical Center Göttingen (UMG), researchers have produced the most complete map to date of how long different proteins persist in many tissues of the body. ...
Mar 21, 2025
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Unlocking dopamine's hidden role: Protective modification of Tau revealed
Using a novel quantitative chemoproteomic strategy, a research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University has uncovered a protective role of dopamine (DA) in regulating ...
Mar 21, 2025
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Dance soothes agitation in Alzheimer's patients
Dancing is known to lift the spirit, and a new study shows that Alzheimer's disease patients respond to the rhythmic moves as well.
Mar 20, 2025
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More young people are caring for a loved one with dementia: It takes a unique toll
Dementia is a growing health problem, affecting more than 55 million people around the world.
Mar 20, 2025
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Anti-amyloid drug shows signs of preventing Alzheimer's dementia
An experimental drug appears to reduce the risk of Alzheimer's-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a study led by the Knight Family Dominantly Inherited ...
Mar 19, 2025
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AI tool creates detailed 3D map of mouse brain metabolism, portending advances in Alzheimer's research
It is a detailed view of the brain like never seen before. In a significant technological leap, University of Florida researchers have created a powerful new computational and artificial intelligence tool that can generate ...
Mar 19, 2025
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Is increased sleepiness in our 80s tied to higher dementia risk?
A study led by Yue Leng, Ph.D., and Sasha Milton, followed the sleep patterns of 733 older female participants to see if specific patterns of change were associated with a higher risk of dementia. The participants, whose ...
Mar 19, 2025
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Earlier menopause and poor synaptic health could raise Alzheimer's risk, says study
Early menopause may be linked to increased risk of Alzheimer's disease among women, according to a study led by researchers at Sunnybrook Health Sciences Centre and the University of Toronto.
Mar 18, 2025
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Latest Alzheimer's drug shown less effective in females than males
Since becoming only the second Alzheimer's-modifying drug to gain American Federal Drug Administration approval in 2023, sales of lecanemab, known by its brand name Leqembi, have risen steadily, reaching $87 million USD in ...
Mar 18, 2025
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Microglia's inflammatory shift: How IL-12 accelerates Alzheimer's damage
Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear away cellular debris—including the plaques typical of Alzheimer's disease. However, as our brains ...
Mar 17, 2025
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