Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma
A new research paper was published in Oncotarget entitled, "Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma."
20 hours ago
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A new research paper was published in Oncotarget entitled, "Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma."
20 hours ago
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New research from Edith Cowan University (ECU) is one step closer to understanding why uveal melanoma, the deadliest form of eye cancer, has such a high rate of metastasis.
Jul 22, 2024
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Early findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may be effective in treating metastatic solid tumors. In the trial, researchers from the National Institutes of Health ...
Jul 11, 2024
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A clinical trial has shown that a new drug combination utilized before surgery completely eliminated or shrunk melanoma tumors in 70% of trial participants. The phase II clinical trial, NeoACTIVATE, enrolled patients with ...
Jul 11, 2024
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Researchers at the University of Bonn have isolated a DNA molecule that is suitable for combating allergic contact dermatitis in mice. The aptamer binds to certain immune system messenger substances, rendering them ineffective. ...
Jul 5, 2024
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Australians are unable to recognize malignant melanomas on their own skin, calling into question the effectiveness of national self-detection guidelines, according to new Southern Cross University research.
Jul 3, 2024
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In many cases of malignant melanoma, the effect of targeted treatment is lost over time. A research team from UZH and USZ has now discovered that a factor secreted by tumor cells is responsible for the resistance. These findings ...
Jun 27, 2024
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For patients with resected stage III melanoma, adjuvant therapy with dabrafenib plus trametinib is associated with a nonsignificant benefit in terms of overall survival, according to a study published in the New England Journal ...
Jun 24, 2024
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It's summer and time to enjoy the sunshine. But it's also important to do so safely. Skin cancer is the most common form of cancer in the United States—and it's most commonly caused by sun exposure. Research has shown that ...
Jun 24, 2024
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A new research perspective titled "When does a melanoma metastasize? Implications for management" has been published in Oncotarget.
Jun 18, 2024
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Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.
Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.
The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.
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