Cancer

Hole-forming protein may suppress tumor growth

Sometimes cells need to die. The process of cell death is encoded within the genome of all higher organisms to kill off cancerous cells, and as a normal part of development to shape a mass of embryonic cells into the organism ...

Cancer

Is your melanoma hot enough for immunotherapy?

Melanomas tend to be "hot" or "cold—if they're hot, immunotherapy lights melanoma tumors like beacons for elimination by the immune system; but 40-50 percent of melanomas are cold, making them invisible to the immune system, ...

Cancer

Gut microbiome directs the immune system to fight cancer

The advent of immune checkpoint inhibitors—which "release the brakes" of the body's immune system to launch an efficient tumor attack—are a major breakthrough in cancer immunotherapy. However, these treatments don't work ...

Other

Dermatology students improve Wikipedia entries on skin disease

A group of medical students recruited to improve Wikipedia articles on skin-related diseases, saw millions more views of those stories following their editing, highlighting the value of expert input on the popular web encyclopedia.

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Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

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