Cancer

New combination treatment flips the switch on melanoma cells

Think of the protein BH3 like a finger that turns off a cancer cell survival switch. The problem is that most cancer cells have found ways to remove this "finger—commonly, by breaking the action of a gene called p53 that ...

Cancer

Fishing for new leads in a rare melanoma

Zebrafish are an emerging power tool in cancer research. They can be engineered to light up when certain genes turn on—capturing the moment when a cancer is initiated. Because they breed so quickly, they lend themselves ...

Cancer

Targeting MC1R in metastatic melanoma

In 1960, scientists described the "Philadelphia chromosome" that causes chronic myeloid leukemia, and in 2001 the Food and Drug Administration approved the drug imatinib to disable the action of this cancer-causing genetic ...

Cancer

Researchers make sense out of the chaos of melanoma

Melanoma is one of the most aggressive tumours, with potential for metastasis from very early stages, when lesions are just millimetres thick. Most puzzling is that these metastases occur in an apparently chaotic way, as ...

Cancer

AAD releases new guidelines for the tx of cutaneous melanoma

(HealthDay)—New guidelines have been released for the treatment of primary cutaneous melanoma, according to a report from the American Academy of Dermatology published online Nov. 1 in the Journal of the American Academy ...

Medical research

Melanoma detection

Melanoma is a type of skin cancer, it is the most lethal of the various forms of this disease. It can be cured but only if detected early enough in its progress. Now, writing in the International Journal of Advanced Intelligence ...

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