Melanoma

Fishing for new leads in a rare melanoma

Zebrafish are an emerging power tool in cancer research. They can be engineered to light up when certain genes turn on—capturing the moment when a cancer is initiated. Because they breed so quickly, they lend themselves ...

Nov 01, 2018
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How melanoma evades targeted therapies

Melanoma is the leading cause of death from skin cancer. Many patients develop metastatic disease that spreads to other parts of the body. One commonly used targeted therapy for metastatic melanomas works by attacking melanomas ...

Nov 06, 2018
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Advancing gene therapy for skin cancer

One of the deadliest skin cancers, melanoma may be caused by overexposure to ultraviolet radiation from the sun or artificial sources such as tanning beds and sunlamps. The Melanoma Network of Canada reports that lifetime ...

Oct 23, 2018
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Cytokine levels could predict immunotherapy problems

The development of immunotherapy, which mobilizes the body's own immune system to destroy cancer cells, is one of the greatest advances in cancer treatment, but immunotherapy can cause harm to healthy tissue in some patients. ...

Oct 31, 2018
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Pathway to resolve allergic asthma is discovered

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a certain protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible ...

Nov 07, 2018
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Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

This text uses material from Wikipedia licensed under CC BY-SA

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