Intermittent food intake activates a 'GPS gene' in liver cells, thus completing the development of the liver after birth
In mammals, the liver detects the body's energy demand at any given moment and mobilizes nutrient reserves to meet it. It is a vital function that is subdivided into multiple tasks: from releasing glucose into the blood when ...
16 hours ago
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Black individuals with a genetic mutation found to have increased risk of developing atrial fibrillation, heart failure
Physician–scientists from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine led a nationwide genetic study examining the role of genetic mutations in the Titin, TTN, gene in Black individuals. ...
16 hours ago
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Overeating and starving both damage the liver: Cavefish provide new insight into fatty liver disease
Fatty liver, which can lead to liver damage and disease, can occur from both overeating and starvation. Now, new research shows how naturally starvation-resistant cavefish, unlike other animals, are able to protect their ...
11 hours ago
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Shining a light on the genetic underpinnings of a rare disease impacting children
A team from the University of Ottawa's Faculty of Medicine has completed a new study that reveals the inner workings of gene mutations that result in an ultra-rare syndrome with fewer than 100 reported cases since its first ...
10 hours ago
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Inhibition of oxidative phosphorylation points to new potential treatment for an intractable genetic disease
A research team led by CiRA Professor Junya Toguchida in collaboration with Assistant Professor Yonghui Jin and graduated student Liping Sun at the Institute for Life and Medical Sciences, Kyoto University, has identified ...
13 hours ago
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How genetic therapies transformed the lives of sickle cell patients
Their stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.
22 hours ago
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Assessing breast cancer risk
The genetic risk of breast cancer has been in the news lately. Researchers at the Mayo Clinic Comprehensive Cancer Center are working toward pinpointing individuals' risk of developing breast cancer.
13 hours ago
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Some lymphomas become resistant to treatment. Gene discovery may offer path to overcome it.
Patients with some types of lymphoma that become resistant to standard treatments may benefit from a therapy that University of Wisconsin–Madison researchers are evaluating after they discovered a key process that fuels ...
Mar 16, 2024
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New insights into genetic mechanisms could improve treatment of liver fibrosis
The liver is not only the largest internal organ but also vital for human life as a metabolic center. It also possesses remarkable self-healing powers: even when large portions are removed, such as during surgery, they quickly ...
Mar 15, 2024
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Newly discovered receptor influences gut development in fruit flies
Adhesion GPCRs are a group of G protein-coupled receptors associated with many bodily functions and diseases in humans. Scientists at Leipzig University have discovered a new receptor—which they have named "mayo"—and ...
Mar 15, 2024
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Researchers identify mutation that alters Alzheimer's disease progression
The scientist of the Faculty of Medicine of the University of Malaga José Luis Royo has coordinated a study that summarizes eight years of research and brings together 100 multidisciplinary specialists, identifying a mutation ...
Mar 15, 2024
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FRYL gene variants linked to a new neurological disorder
A recent study from the lab of Dr. Hugo J. Bellen, distinguished service professor at Baylor College of Medicine and investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) links the FRYL gene ...
Mar 14, 2024
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Research reveals the genetic code behind non-identical twins
A QIMR Berghofer-led international team of scientists has unlocked the genetic secrets behind why some mothers are more likely than others to conceive twins.
Mar 14, 2024
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Tissue samples show the deep genetic and cellular impacts of smoking
It's no secret that smoking is extremely detrimental to health. Tobacco smoke contains thousands of chemicals, including carcinogens, increasing the risk of cancer, cardiovascular and respiratory diseases.
Mar 14, 2024
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Cell division, DNA repair and cancer progression closely tied to CDK9 dysfunction
Researchers describe a newly observed role for the protein Cyclin Dependent Kinase 9 (CDK9) in regulating DNA repair during cellular division, where errors can become the origin of cancerous tumor growth. Through a process ...
Mar 14, 2024
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Researchers may have found key to deprogram cells that lead to transplant rejection
Houston Methodist researchers identified a troublesome subset of T-cells in transplant recipients that may be a more effective therapeutic target for preventing transplant rejection in patients.
Mar 14, 2024
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Protein discovery sparks treatment hope for aggressive cancer
Researchers have found a new way to potentially treat one of the most common forms of acute lymphoblastic leukemia.
Mar 14, 2024
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Shedding new light on brain calcification
Brain calcification can cause movement disorders and cognitive impairment. Researchers at the Arnesen Lab at UiB have now identified a gene that provides new insight into how these calcifications occur.
Mar 14, 2024
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