Researchers added a scaffold/matrix attachment region (S/MAR) to a conventional adeno-associated virus (AAV) vector used for gene transfer, and the modified vectors were able to establish colonies and maintain long-term transgene ...
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A new syndrome caused by biallelic mutations in the FANCM gene predisposes the body to the appearance of tumours and causes rejection to chemotherapy treatments. Contrary to what scientists believed, the gene does not cause ...
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Whenever I work on a new edition of my human genetics textbook and reach the section on eugenics, at the end of an evolution chapter, I'm relieved that it's history. But this summer, as I wrapped up the 12th edition, the ...
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We've probably all heard of mitochondria, and we may even remember learning in school that they are the "powerhouses of the cell" – but what does that actually mean, and how did they evolve? To answer this question, we ...
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Intricate human physiological features such as the immune system require exquisite formation and timing to develop properly. Genetic elements must be activated at just the right moment, across vast distances of genomic space.
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In a major study published today, researchers at deCODE genetics use whole-genome data from 14,000 people from across the population of Iceland, including 1500 sets of parents and children, to provide the most detailed portrait ...
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Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development. This is the first time that genome editing has been used to study gene function in human ...
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A leading cause of glaucoma and blindness is exfoliation syndrome, or XFS, an age-related disorder that results in excess fibrous material building up. Now, A*STAR scientists, along with an international research team, have ...
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Previous research has shown that there is a connection between epigenetic changes and some of our common illnesses. But what does this connection mean? A new study shows that external factors, such as lifestyle aspects, often ...
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When it comes to male reproductive fertility, timing is everything. Now scientists are finding new details on how disruption of this timing may contribute to male infertility or congenital illness.
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