Genetics

IQSEC1 gene mutations cause new intellectual disability syndrome

It used to take several years or sometimes decades to unequivocally identify the genes that cause rare human syndromes that affect very few individuals. Nowadays, however, human geneticists and fly and mouse biologists have ...

Genetics

Machine learning's next frontier: Epigenetic drug discovery

Machine learning's powerful ability to detect patterns in complex data is revolutionizing how we drive, how we diagnose disease and now, how we discover new drugs. Scientists at Sanford Burnham Prebys Medical Discovery Institute ...

Genetics

Inequality now extends to people's DNA

It's well known that some areas of the UK are poorer than others. These include Wales and northern Britain, which used to be coal-mining areas. Now we have discovered that these regional economic inequalities are in line ...

Genetics

Gene variants influence size of brainstem, other structures

Researchers have found a link between 48 common genetic variations and the size of the brainstem and other subcortical structures deep within the brain. These structures control a wide array of functions ranging from learning ...

Oncology & Cancer

Silencing RNA nanotherapy shows promise against pancreatic cancer

Despite advances in cancer survival, more than 90 percent of people with pancreatic cancer die within five years. Most patients with pancreatic tumors (and half of those with colorectal cancers) carry a mutation in the KRAS ...