The epigenetic modifier MLL4 has an unassuming name—the 4, for instance, indicates it's just one in a family of such modifiers. But MLL4 is quite special: In a specific type of leukemia, it drives disease progression, while ...
Jul 10, 2026
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Rare DNA changes are most strongly linked to cognition in early childhood, but the link fades as children age, while common DNA changes show stronger links later in childhood, a new study finds. The research was reported ...
Jul 10, 2026
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In a global breakthrough published in Nature Genetics, researchers have successfully mapped the cells and genes that regulate bone formation and loss at an unprecedented scale and discovered the critical role that blood vessel ...
Jul 10, 2026
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New research, led by scientists from the Seaver Autism Center for Research and Treatment at Mount Sinai and published in Autism Research, has estimated that Phelan-McDermid syndrome (PMS) affects approximately 1 in 7,300 ...
Jul 10, 2026
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Rat disease models have played an integral role in scientific discovery and cancer research, including Nobel Prize–winning work from Charles Huggins on hormone therapy for prostate cancer in 1966. However, technical challenges ...
Jul 9, 2026
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Researchers at the University of British Columbia have identified a new form of hereditary prostate cancer that, while rare, can cause aggressive disease at a young age. The discovery paves the way for genetic testing programs ...
Jul 9, 2026
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Irritable bowel syndrome (IBS) is a common condition that affects more than 10% of the general population, causing recurrent abdominal pain, bloating, constipation and diarrhea. IBS is considered a disorder of gut-brain interaction, ...
Jul 9, 2026
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Researchers have solved a long-standing mystery of how abnormal chromosomes drive cancer, identifying 81 new genes involved in aggressive breast cancer. The discovery expands understanding of the cellular processes behind ...
Jul 8, 2026
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Early detection and treatment of congenital cerebral ventriculomegaly (CCV)—when a fetus's fluid-filled brain ventricles swell due to a condition called hydrocephalus—can help clinicians prevent developmental or neurological ...
Jul 8, 2026
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A new study describes a gene therapy strategy that uses the brain's own glymphatic transport system to distribute engineered viral vectors throughout the brain. The approach addresses two major challenges in neurological ...
Jul 8, 2026
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