Some of the most harmful genetic changes in cancer are also the hardest to see. These structural alterations, deep within a tumor's DNA, can fuel aggressive growth and evade standard testing, especially when tissue samples ...
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The relationship between genetic variants and the risk of late-onset cardiomyopathy remains poorly understood in survivors of childhood cancer despite being otherwise well established. Scientists from St. Jude Children's ...
7 hours ago
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A new laboratory method developed by researchers at Columbia University Vagelos College of Physicians and Surgeons may now help physicians more quickly diagnose patients with suspected genetic disorders of the immune system, ...
Jun 20, 2025
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Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host's cellular machinery to make new copies of themselves. Herpes simplex virus-1 (HSV-1), it turns ...
Jun 19, 2025
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Scientists at the USC Leonard Davis School of Gerontology have discovered a key connection between high levels of iron in the brain and increased cell damage in people who have both Down syndrome and Alzheimer's disease.
Jun 19, 2025
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A multidisciplinary team has taken a step forward in the field of precision medicine with the publication of a study that highlights the value of integrating multiple layers of biological information—genomic, metabolomic, ...
Jun 19, 2025
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Researchers have found a promising new method for gene therapy. They successfully restarted inactive genes by bringing them closer to genetic switches on the DNA called enhancers. The intermediate piece of DNA was cut out ...
Jun 19, 2025
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Researchers from Children's Hospital of Philadelphia (CHOP) have identified a novel gene associated with neurodevelopmental disorders and epilepsy. The study, published in the American Journal of Human Genetics, leveraged ...
Jun 19, 2025
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"Biological stochasticity"—random events at the molecular and cellular level—might be one of the biggest, most overlooked drivers of differences in how we age, says Ryo Sanabria.
Jun 19, 2025
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A research team at the University of Osaka has unveiled the molecular mechanism behind genome ejection from adeno-associated virus (AAV) vectors, a crucial delivery vehicle in gene therapy.
Jun 19, 2025
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