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Rheumatology news
Imbalances in the oral microbiome linked to symptomatic hand osteoarthritis
A study published online in the open-access journal RMD Open has linked specific imbalances and disruptions in the oral microbiome to symptomatic hand arthritis.
18 hours ago
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Timing of JAK initiation, shingles vaccine administration can affect outcomes in rheumatoid arthritis
For patients with rheumatoid arthritis (RA), the timing of Janus kinase (JAK) inhibitor initiation relative to administration of recombinant zoster vaccine (RZV) can affect early response and arthritis control, according ...
17 hours ago
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Interferon alpha may drive Sjögren's disease in 60% of patients
Interferon alpha is an inflammatory mediator that can cause Sjögren's syndrome, an autoimmune disease. This was revealed in a study carried out by University Hospital Bonn together with the University of Bonn, the University ...
Jul 20, 2026
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The bone fractures that often go unlinked to osteoporosis
Many fractures are early-warning signs of osteoporosis. Yet in everyday clinical care, they often go unrecognized and undocumented as warning signs, according to a new nationwide Austrian study by the Complexity Science Hub ...
Jul 20, 2026
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Melatonin may help ease chronic muscle and joint pain, new study suggests
Melatonin is best known for helping us sleep. But a new study suggests it might have another surprising use: easing muscle and joint pain.
Jul 16, 2026
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Bimekizumab well tolerated, efficacious over three years in axial spondyloarthritis
For patients with axial spondyloarthritis (axSpA), bimekizumab, a dual interleukin (IL)-17A and IL-17F inhibitor, is well tolerated over three years, according to a study published in the June issue of the Journal of Rheumatology.
Jul 9, 2026
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New data highlight off-the-shelf iPSC-derived CAR T-cell therapy for treatment-resistant systemic sclerosis
New preliminary clinical data presented at ISSCR 2026 evaluated an induced pluripotent stem cell (iPSC)-derived CAR T-cell therapy for patients with treatment-resistant systemic sclerosis, a rare autoimmune disease with high ...
Jul 9, 2026
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Longer persistence seen with Upadacitinib versus tumor necrosis factor inhibitors in rheumatoid arthritis
Patients with rheumatoid arthritis (RA) have longer persistence with upadacitinib than tumor necrosis factor inhibitors (TNFi), according to a study published online June 23 in Rheumatology.
Jul 6, 2026
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New expert recommendations aim to improve detection and care of lung disease in people with rheumatoid arthritis
A new international expert consensus statement published in The Lancet Respiratory Medicine provides guidance for doctors on how to identify, monitor and treat a serious lung complication that affects many people living with ...
Jul 2, 2026
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A new framework to advocate for improving the quality of life of people with rheumatic and musculoskeletal diseases
Rheumatic and musculoskeletal diseases (RMDs) contribute significantly to the disability and health care burden in Europe, but until now there has been no harmonized, specific data set to help systematically compare differences ...
Jul 1, 2026
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First potential probiotic treatment for lupus identified by researchers
Scientists at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have found a link between a bacterium in the gut microbiome (ecosystem) and lupus that could lead to more effective ...
Jun 25, 2026
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Patients with lupus have increased risk of chronic kidney disease, mortality
Patients with systemic lupus erythematosus (SLE) without lupus nephritis (LN) have increased risk of chronic kidney disease (CKD) and mortality, according to a study published June 16 in Rheumatology.
Jun 25, 2026
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Immune cell–fibroblast crosstalk may be the key trigger of autoimmune diseases
In autoimmune disorders, immune cells targeting "self" proteins are mistakenly activated, resulting in abnormal expansion and responsiveness. These disorders are known to reduce patients' quality of life over a prolonged ...
Jun 24, 2026
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Hidden mechanism driving joint tissue growth in rheumatoid arthritis has been found
Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that plays a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into ...
Jun 24, 2026
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Ultrasound-based approach may reduce harmful inflammation and support joint healing
As an aging population experiences joint pain and inflammation at an all-time high, researchers at The University of Alabama in Huntsville (UAH), a part of The University of Alabama System, have published new findings suggesting ...
Jun 19, 2026
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CAR T-cell therapy shows early promise in severe lupus
Early results from a UCL- and UCLH-led clinical trial suggest that a type of CAR T-cell therapy—developed by Autolus Therapeutics, a UCL spinout—could offer a new treatment approach for people with severe, treatment-resistant ...
Jun 15, 2026
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Biological content of blood-derived treatment could affect common arthritis
Injections of platelet-rich plasma made from a patient's own blood are increasingly used to treat knee osteoarthritis, but their use is not widely accepted, and the treatment does not work for everyone. Investigators from ...
Jun 15, 2026
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Scientists reveal an autoimmune vicious cycle in Sjögren's disease
Sjögren's disease is a widespread chronic autoimmune disorder that attacks the body's own glands, yet its underlying disease mechanisms remain poorly understood. In a recent study, researchers from Japan discovered a self-reinforcing ...
Jun 11, 2026
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Drug reduces the risk of developing rheumatoid arthritis, clinical trial finds
A clinical trial led by researchers from Hospital Clínic de Barcelona, the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) and the Institute of Advanced Chemistry of Catalonia (IQAC-CSIC) compared the effectiveness ...
Jun 10, 2026
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How modern rheumatoid arthritis treatments can protect bone health
A new review published in Calcified Tissue International highlights major advances in understanding and preventing bone loss in people with rheumatoid arthritis (RA), showing that modern antirheumatic therapies can significantly ...
Jun 10, 2026
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Challenges of vitamin D management in inflammatory rheumatic diseases highlighted in review
A new review from the International Osteoporosis Foundation (IOF) Osteoimmunology Working Group, published in Osteoporosis International, provides a comprehensive evaluation of the role of vitamin D in inflammatory rheumatic ...
Jun 8, 2026
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Common arthritis drugs reduce systemic Sjögren's disease activity in 24 weeks
A combination of two widely available anti-rheumatic drugs offers the first effective and affordable treatment for patients with Sjögren's disease with systemic disease activity, according to new results from a clinical trial ...
Jun 6, 2026
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New drug cuts relapse risk by half in rare immune disorder trial
Stanford Medicine researchers and their colleagues found that a new drug, obexelimab, significantly reduces the risk of relapse in patients with IgG4-related disease, a rare chronic immune condition often misdiagnosed as ...
Jun 4, 2026
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Largest study of knee osteoarthritis tissue reveals core biological pathways underlying the disease
A major international study led by researchers at the Kennedy Institute of Rheumatology at the University of Oxford has found that osteoarthritis (OA)—the most common form of arthritis worldwide—is not a collection of separate ...
Jun 2, 2026
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New RNA sequencing method reveals hidden layer of immune system control
Researchers at University Medical Center Utrecht have uncovered a previously underappreciated mechanism that helps immune cells to respond rapidly to infections. Using advanced long-read RNA sequencing, the team shows that ...
Jun 2, 2026
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