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Rheumatology news
Lupus patients can lower their heart disease risk by sticking to one common treatment, study says
Lupus patients can significantly decrease their risk of heart disease if they consistently take their medication, a new study says. People with lupus had a higher risk of heart disease if they didn't consistently take hydroxychloroquine ...
16 hours ago
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The body's warmth sensor is secretly a pain switch—blocking it may ease arthritis
Chronic pain, including arthritis pain, affects more than one-third of U.K. adults. Current painkillers such as methotrexate and nonsteroidal anti-inflammatory drugs (NSAIDs) work by damping down the immune system, which ...
Sep 17, 2026
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Why an overactive immune system attacks the bodies of people with lupus but still leaves them vulnerable to infection
Despite having an overactive immune system, people with lupus may still struggle to fight bacterial infections. My team and I found that this paradox may result from chronic inflammation pushing their immune cells toward ...
Sep 16, 2026
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Antiviral defense gained at the cost of autoimmunity risk, study shows
Why do genetic variants that increase the risk of autoimmune disease remain so common in the population?
Sep 11, 2026
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Rheumatoid arthritis: Timely diagnosis and early treatment initiation are key determinants of prognosis
Early, consistently managed treatment can have a decisive impact on the course of rheumatoid arthritis and prevent permanent joint damage. An international review led by Josef S. Smolen of the Medical University of Vienna ...
Sep 11, 2026
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When should patients see a rheumatologist for chronic back pain?
Axial spondyloarthritis (axSpA) is an inflammatory condition that causes chronic back pain and, if left untreated, can lead to fusion of the spinal or sacroiliac joints. The condition frequently remains underdiagnosed, with ...
Sep 10, 2026
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Should adults with autoimmune rheumatic conditions receive updated COVID-19 vaccines?
In an Arthritis & Rheumatology analysis of data on 60,980 U.S. adults with autoimmune rheumatic conditions who developed COVID-19 between December 2020 and August 2024, those who received booster or updated (2023–2024) COVID-19 ...
Sep 9, 2026
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Experimental study points to systemic sclerosis treatment
Investigators at Cedars-Sinai Health Sciences University used an experimental drug to reverse the effects of systemic sclerosis, a serious autoimmune disease. The study, conducted in a laboratory, was published in JCI Insight.
Sep 8, 2026
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Distinct characteristics identified for patients with rheumatoid conditions, opioid use disorder
Patients with rheumatic conditions and opioid use disorder (OUD) have distinct demographic and clinical characteristics, including lower use of disease-modifying antirheumatic drugs (DMARDs) and higher acute care use, according ...
Sep 8, 2026
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Scientists uncover shared biology behind profound fatigue in five major illnesses
A shared biological mechanism that helps explain chronic exhaustion in conditions including long COVID and PTSD has been identified by researchers at the University of East Anglia and Oxford BioDynamics. The paper, published ...
Sep 2, 2026
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FDA approves Lisraya for dermatomyositis in adults
The U.S. Food and Drug Administration has approved Lisraya (brepocitinib) tablets as the first oral treatment for dermatomyositis in adults.
Sep 1, 2026
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Stress proteins actively sustain joint inflammation in osteoarthritis, study finds
Why do some joints remain chronically inflamed in osteoarthritis and other rheumatic diseases? Researchers have taken an important step toward answering this question. Their findings, published in the journal Cell Death & ...
Aug 31, 2026
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Immune cells that drive harmful autoantibody responses after COVID-19 identified
When the immune system encounters a virus, it produces antibodies designed to recognize and eliminate the invader. But in some people infected with SARS-CoV-2, the virus that causes COVID-19, the immune response goes awry, ...
Aug 28, 2026
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Cell therapy substantially reduces severe rheumatoid arthritis in first clinical trial
Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific therapies, manufactured from patients' own immune cells, could also help cure autoimmune diseases. Six patients ...
Aug 27, 2026
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Older Australians in the dark about osteoporosis, research finds
New Curtin University research has found a concerning lack of knowledge about osteoporosis among older Australians, with many unaware of the exercises that can protect their bones and reduce their risk of falls.
Aug 27, 2026
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France recalls rare disease drug Tavneos after deaths
A drug called Tavneos, used to treat rare autoimmune diseases, will be pulled from shelves in France, the country's medicine watchdog said Wednesday, after it was linked to 20 deaths in Japan.
Aug 19, 2026
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Better measurement for better calcinosis cutis treatment
Calcinosis cutis is a condition that causes calcium deposits in a person's skin or soft tissues. These deposits can occur anywhere in the body and, depending on their location, can be disabling for patients. For example, ...
Aug 19, 2026
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New cellular clues to complications of scleroderma
A study published in JCI Insight and led by Northwestern Medicine scientists has uncovered new clues about why people with systemic sclerosis, also known as scleroderma, frequently develop debilitating esophageal complications.
Aug 17, 2026
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Pregnancy increases immune burden on women with arthritis and lupus
When a new life begins to grow in the mother's womb, the immune system must perform a demanding balancing act: It must tolerate the fetus, which is genetically half foreign, and at the same time protect the mother from infection. ...
Aug 13, 2026
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Arthritis origins may begin before birth
Researchers at the Kennedy Institute have discovered that some joints may be more susceptible to inflammatory arthritis before birth, offering new insight into why rheumatoid arthritis attacks particular joints while sparing ...
Aug 12, 2026
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Scientists uncover drivers of recurrent arthritis after immunotherapy, suggesting potential biomarkers
A new study led by researchers at The University of Texas MD Anderson Cancer Center has shown that inflammatory arthritis occurring as a side effect of immune checkpoint inhibitors behaves like an immune-memory disease, suggesting ...
Aug 12, 2026
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Key genetic differences between pediatric and adult forms of immune-mediated inflammatory diseases identified
Researchers from Children's Hospital of Philadelphia (CHOP) have found that pediatric-onset rheumatic and inflammatory diseases have distinct genetic architecture compared with those in adults. The findings, published today ...
Aug 12, 2026
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Socioeconomic status shapes treatment timing and duration in arthritis patients
A study initiated by the European Spondyloarthritis Research Collaboration Network (EuroSpA) examined whether patients' countries of residence are associated with the severity of their psoriatic arthritis (PsA) or axial spondyloarthritis ...
Aug 11, 2026
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Study: Variable outcomes of stem cell injections for knee osteoarthritis
Knee osteoarthritis (KOA) affects more than 1 in 10 people older than 40, impairing patients' mobility and quality of life. With limited treatment options, stem cell injections have been promoted as a treatment, but clinical ...
Aug 7, 2026
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Air pollution linked to spikes in rheumatoid arthritis activity and flare risk
A study shows that exposure to air pollution, especially fine particulate matter like dust, soot and smoke (PM2.5), is associated with increased disease activity and flare risk in rheumatoid arthritis (RA).
Aug 5, 2026
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