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Rheumatology news
New insights into why the sun makes lupus patients sick
Researchers from University of Michigan Health have mapped the cellular path of inflammation after UV exposure in lupus patients.
16 hours ago
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Pausing certain arthritis drugs after COVID-19 vaccination raises flare risk without improving antibody response
For patients with inflammatory arthritis, holding certain disease-modifying antirheumatic drugs (DMARDs), namely select biologic or Janus kinase inhibitor (JAKi) therapies, for two weeks at the time of a supplemental COVID-19 ...
12 hours ago
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1 in 3 with lupus takes supplements, medications with potential for interactions
Nearly 1 in 3 patients with systemic lupus erythematosus (SLE) are taking a supplement-medication combination with potential for an interaction, according to a study published online Sept. 22 in Arthritis Care & Research.
11 hours ago
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Inherited lupus can begin early—and continue silently
A multicenter study led by researchers at Sultan Qaboos University has found that patients with a rare inherited form of lupus may continue to accumulate organ damage even when conventional measures indicate that their disease ...
14 hours ago
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International consensus sets updated framework for CAR T-cell therapy in severe autoimmune diseases
An international multidisciplinary group of 31 experts has updated consensus recommendations to guide the use of CAR T-cell therapy in patients with severe, treatment-refractory autoimmune diseases.
11 hours ago
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Chemistry professors' patent detects amino acid linked to M.S., rheumatoid arthritis, cancer
More than a decade of work by two University of Wisconsin-Stout Polytechnic faculty members and their student researchers has led to a newly patented process that allows for the easy detection of an amino acid linked to multiple ...
Oct 1, 2026
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A missing piece in the cell death and inflammation signaling pathway puzzle has been revealed
An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways involved in programmed cell death. The team identified the protein HERC4 as an essential component ...
Sep 28, 2026
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How the treatment of interleukin-6-driven diseases can be refined
Interleukin-6 (IL-6) is a contradictory molecule in immunology. It helps the liver regenerate after injury and protects against infections, yet it also drives chronic inflammation in rheumatic diseases, inflammatory bowel ...
Sep 25, 2026
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International study sets new standards for arthritis ultrasound diagnosis
People with early inflammatory arthritis could benefit from faster and more accurate diagnosis following a major international study that has established, for the first time, age-specific ultrasound standards to distinguish ...
Sep 23, 2026
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Rheumatic immune-related adverse events with immune checkpoint inhibitors more severe than previously reported
For patients receiving immune checkpoint inhibitors (ICIs), rheumatic immune-related adverse events (rh-irAEs) are usually moderate or severe, with more than one-third leading to permanent ICI discontinuation, according to ...
Sep 22, 2026
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Lupus patients can lower their heart disease risk by sticking to one common treatment, study says
Lupus patients can significantly decrease their risk of heart disease if they consistently take their medication, a new study says. People with lupus had a higher risk of heart disease if they didn't consistently take hydroxychloroquine ...
Sep 21, 2026
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The body's warmth sensor is secretly a pain switch—blocking it may ease arthritis
Chronic pain, including arthritis pain, affects more than one-third of U.K. adults. Current painkillers such as methotrexate and nonsteroidal anti-inflammatory drugs (NSAIDs) work by damping down the immune system, which ...
Sep 17, 2026
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Why an overactive immune system attacks the bodies of people with lupus but still leaves them vulnerable to infection
Despite having an overactive immune system, people with lupus may still struggle to fight bacterial infections. My team and I found that this paradox may result from chronic inflammation pushing their immune cells toward ...
Sep 16, 2026
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Antiviral defense gained at the cost of autoimmunity risk, study shows
Why do genetic variants that increase the risk of autoimmune disease remain so common in the population?
Sep 11, 2026
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Rheumatoid arthritis: Timely diagnosis and early treatment initiation are key determinants of prognosis
Early, consistently managed treatment can have a decisive impact on the course of rheumatoid arthritis and prevent permanent joint damage. An international review led by Josef S. Smolen of the Medical University of Vienna ...
Sep 11, 2026
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When should patients see a rheumatologist for chronic back pain?
Axial spondyloarthritis (axSpA) is an inflammatory condition that causes chronic back pain and, if left untreated, can lead to fusion of the spinal or sacroiliac joints. The condition frequently remains underdiagnosed, with ...
Sep 10, 2026
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Should adults with autoimmune rheumatic conditions receive updated COVID-19 vaccines?
In an Arthritis & Rheumatology analysis of data on 60,980 U.S. adults with autoimmune rheumatic conditions who developed COVID-19 between December 2020 and August 2024, those who received booster or updated (2023–2024) COVID-19 ...
Sep 9, 2026
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Experimental study points to systemic sclerosis treatment
Investigators at Cedars-Sinai Health Sciences University used an experimental drug to reverse the effects of systemic sclerosis, a serious autoimmune disease. The study, conducted in a laboratory, was published in JCI Insight.
Sep 8, 2026
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Distinct characteristics identified for patients with rheumatoid conditions, opioid use disorder
Patients with rheumatic conditions and opioid use disorder (OUD) have distinct demographic and clinical characteristics, including lower use of disease-modifying antirheumatic drugs (DMARDs) and higher acute care use, according ...
Sep 8, 2026
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Scientists uncover shared biology behind profound fatigue in five major illnesses
A shared biological mechanism that helps explain chronic exhaustion in conditions including long COVID and PTSD has been identified by researchers at the University of East Anglia and Oxford BioDynamics. The paper, published ...
Sep 2, 2026
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FDA approves Lisraya for dermatomyositis in adults
The U.S. Food and Drug Administration has approved Lisraya (brepocitinib) tablets as the first oral treatment for dermatomyositis in adults.
Sep 1, 2026
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Stress proteins actively sustain joint inflammation in osteoarthritis, study finds
Why do some joints remain chronically inflamed in osteoarthritis and other rheumatic diseases? Researchers have taken an important step toward answering this question. Their findings, published in the journal Cell Death & ...
Aug 31, 2026
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Immune cells that drive harmful autoantibody responses after COVID-19 identified
When the immune system encounters a virus, it produces antibodies designed to recognize and eliminate the invader. But in some people infected with SARS-CoV-2, the virus that causes COVID-19, the immune response goes awry, ...
Aug 28, 2026
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Cell therapy substantially reduces severe rheumatoid arthritis in first clinical trial
Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific therapies, manufactured from patients' own immune cells, could also help cure autoimmune diseases. Six patients ...
Aug 27, 2026
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Older Australians in the dark about osteoporosis, research finds
New Curtin University research has found a concerning lack of knowledge about osteoporosis among older Australians, with many unaware of the exercises that can protect their bones and reduce their risk of falls.
Aug 27, 2026
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