New cellular clues to complications of scleroderma
A study published in JCI Insight and led by Northwestern Medicine scientists has uncovered new clues about why people with systemic sclerosis, also known as scleroderma, frequently develop debilitating esophageal complications.
Aug 17, 2026
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Pregnancy increases immune burden on women with arthritis and lupus
When a new life begins to grow in the mother's womb, the immune system must perform a demanding balancing act: It must tolerate the fetus, which is genetically half foreign, and at the same time protect the mother from infection. ...
Aug 13, 2026
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Arthritis origins may begin before birth
Researchers at the Kennedy Institute have discovered that some joints may be more susceptible to inflammatory arthritis before birth, offering new insight into why rheumatoid arthritis attacks particular joints while sparing ...
Aug 12, 2026
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Scientists uncover drivers of recurrent arthritis after immunotherapy, suggesting potential biomarkers
A new study led by researchers at The University of Texas MD Anderson Cancer Center has shown that inflammatory arthritis occurring as a side effect of immune checkpoint inhibitors behaves like an immune-memory disease, suggesting ...
Aug 12, 2026
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Key genetic differences between pediatric and adult forms of immune-mediated inflammatory diseases identified
Researchers from Children's Hospital of Philadelphia (CHOP) have found that pediatric-onset rheumatic and inflammatory diseases have distinct genetic architecture compared with those in adults. The findings, published today ...
Aug 12, 2026
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Socioeconomic status shapes treatment timing and duration in arthritis patients
A study initiated by the European Spondyloarthritis Research Collaboration Network (EuroSpA) examined whether patients' countries of residence are associated with the severity of their psoriatic arthritis (PsA) or axial spondyloarthritis ...
Aug 11, 2026
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Study: Variable outcomes of stem cell injections for knee osteoarthritis
Knee osteoarthritis (KOA) affects more than 1 in 10 people older than 40, impairing patients' mobility and quality of life. With limited treatment options, stem cell injections have been promoted as a treatment, but clinical ...
Aug 7, 2026
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Air pollution linked to spikes in rheumatoid arthritis activity and flare risk
A study shows that exposure to air pollution, especially fine particulate matter like dust, soot and smoke (PM2.5), is associated with increased disease activity and flare risk in rheumatoid arthritis (RA).
Aug 5, 2026
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Lupus-linked immune misdirection could leave patients vulnerable to staph infections
Microbiology researchers from the University of Tennessee, Knoxville, have discovered why patients with the autoimmune disease lupus are susceptible to serious bacterial infections. Their new study published in Cell Press ...
Aug 3, 2026
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New insights into genetic architecture of a rare systemic inflammatory disease in East Asian populations
Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic inflammatory disease characterized by eosinophilia, an abnormal increase in eosinophils—a type of white blood cell—and inflammation of small blood vessels ...
Aug 3, 2026
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Why eGoT gets better answers: Teaching AI to connect the dots across domains
Ever notice how chatbots often insist on making up an answer instead of admitting defeat? Like a student desperately scribbling nonsense to avoid handing in a blank page, large language models (LLMs) seem to live by the make-it-up-as-you-go ...
Jul 31, 2026
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Genetic risk factors of fibromyalgia identified in largest study of its kind
New genetic risk factors have been identified for fibromyalgia syndrome in a landmark study that involved scientists at King's College London. The study, published in Nature Medicine, highlights how the nervous system plays ...
Jul 28, 2026
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Colorado was the first state to cap a drug's price. Then a federal court stepped in
Colorado is one of a handful of states with a review board for drug prices and one of only four with a board empowered to set upper limits on what state agencies, insurers and other purchasers may pay or be reimbursed for ...
Jul 25, 2026
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Beyond inflammation: Caspase-11's unexpected role in bone remodeling
Millions of people worldwide suffer from osteoporosis, a disease marked by progressive bone loss, weakened skeletal strength and increased fracture risk. Healthy bone is maintained through continuous remodeling, where osteoblasts ...
Jul 24, 2026
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Imbalances in the oral microbiome linked to symptomatic hand osteoarthritis
A study published online in the open-access journal RMD Open has linked specific imbalances and disruptions in the oral microbiome to symptomatic hand arthritis.
Jul 21, 2026
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Timing of JAK initiation, shingles vaccine administration can affect outcomes in rheumatoid arthritis
For patients with rheumatoid arthritis (RA), the timing of Janus kinase (JAK) inhibitor initiation relative to administration of recombinant zoster vaccine (RZV) can affect early response and arthritis control, according ...
Jul 21, 2026
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Interferon alpha may drive Sjögren's disease in 60% of patients
Interferon alpha is an inflammatory mediator that can cause Sjögren's syndrome, an autoimmune disease. This was revealed in a study carried out by University Hospital Bonn together with the University of Bonn, the University ...
Jul 20, 2026
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The bone fractures that often go unlinked to osteoporosis
Many fractures are early-warning signs of osteoporosis. Yet in everyday clinical care, they often go unrecognized and undocumented as warning signs, according to a new nationwide Austrian study by the Complexity Science Hub ...
Jul 20, 2026
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Melatonin may help ease chronic muscle and joint pain, new study suggests
Melatonin is best known for helping us sleep. But a new study suggests it might have another surprising use: easing muscle and joint pain.
Jul 16, 2026
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New data highlight off-the-shelf iPSC-derived CAR T-cell therapy for treatment-resistant systemic sclerosis
New preliminary clinical data presented at ISSCR 2026 evaluated an induced pluripotent stem cell (iPSC)-derived CAR T-cell therapy for patients with treatment-resistant systemic sclerosis, a rare autoimmune disease with high ...
Jul 9, 2026
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Bimekizumab well tolerated, efficacious over three years in axial spondyloarthritis
For patients with axial spondyloarthritis (axSpA), bimekizumab, a dual interleukin (IL)-17A and IL-17F inhibitor, is well tolerated over three years, according to a study published in the June issue of the Journal of Rheumatology.
Jul 9, 2026
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Longer persistence seen with Upadacitinib versus tumor necrosis factor inhibitors in rheumatoid arthritis
Patients with rheumatoid arthritis (RA) have longer persistence with upadacitinib than tumor necrosis factor inhibitors (TNFi), according to a study published online June 23 in Rheumatology.
Jul 6, 2026
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New expert recommendations aim to improve detection and care of lung disease in people with rheumatoid arthritis
A new international expert consensus statement published in The Lancet Respiratory Medicine provides guidance for doctors on how to identify, monitor and treat a serious lung complication that affects many people living with ...
Jul 2, 2026
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