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Rethinking mRNA vaccines: Liver targeting can suppress immunity, while muscle boosts it
A new study by researchers at the Icahn School of Medicine at Mount Sinai overturns a longstanding assumption about how mRNA vaccines generate immunity, revealing that certain non-immune cells help determine vaccine effectiveness.
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Not all organs age alike: AI unveils the molecular impact of menopause across the female body
Despite affecting half of the world's population, menopause has historically been understudied and misunderstood, both in biomedical research and clinical practice. However, with the increase in life expectancy, the number ...
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Medical research news
Microplastics turn up in nearly every human brain sample, including healthy tissue
Tiny micro- and nanoplastic fragments seem to be turning up everywhere, including one of the most well-protected parts of the human body—the brain. In a recent study conducted by Chinese researchers, they found microplastics ...
Cancer cells can rewrite RNA messages, creating new drug targets in aggressive tumors
Scientists have uncovered an unexpected way cells can generate cancer-driving proteins—by cutting RNA into shorter, functional fragments rather than following the standard blueprint. This process, newly termed as "RNA dicing," ...
11 hours ago
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How the immune system battles lifelong viral infections acquired at birth
Millions of people worldwide carry viral infections they acquired at birth, often for life. For a long time it was assumed that the immune system hardly fights these pathogens. Researchers from the University of Basel show ...
10 hours ago
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Macaques reveal human-like genetic cause of inherited blindness, offering new disease model
An inherited form of blindness directly comparable to a common inherited optic nerve disease in humans has been discovered in rhesus macaques at the California National Primate Research Center at the University of California, ...
12 hours ago
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Excessive cholesterol in astrocytes linked to cognitive decline in Alzheimer's mice
Alzheimer's disease (AD) is a neurodegenerative disorder that leads to progressive memory loss and a decline in mental functions. Several past studies have linked this disease to the accumulation of the protein amyloid-β ...
AI model detects normally 'invisible' tissue changes of pancreatic cancer at stage 0
An AI model (REDMOD) can pick up the very early subtle tissue changes of pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer, which conventional imaging and the human eye find difficult to detect, ...
12 hours ago
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A banned chemical still lingers, and its strangest effect may depend on sex, genes and one common vitamin
In two new studies, researchers at the UC Davis MIND Institute have clarified how a long-banned group of chemicals, called polychlorinated biphenyls (PCBs), affect genetic activity. The research helps explain how biological ...
12 hours ago
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Smart soft sensors restore surgeons' sense of touch in minimally invasive procedures
Researchers at NYU Abu Dhabi have developed soft, flexible sensors that help restore a surgeon's sense of touch during minimally invasive (keyhole) surgery. These procedures allow for faster recovery and less pain, but surgeons ...
12 hours ago
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How bones make marrow: Newly identified 'organizer' cells also reappear after fractures
Bone marrow is the spongy tissue located within the hollow center of bones, serving as the primary site for the continuous production of red blood cells, platelets, and white blood cells. Despite its physiological importance, ...
13 hours ago
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Digital twin can reveal alcohol consumption in crime cases
Using a so-called digital twin, it is possible to predict with greater precision than at present how much alcohol a person has consumed and at what time. The study was conducted by researchers at Linköping University and ...
12 hours ago
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From gut to brain: Scientists engineer bacteria to treat severe liver-related brain dysfunction
When the liver fails, toxins—such as ammonia—that should be filtered from the blood build up and reach the brain. The result is hepatic encephalopathy (HE), a devastating neurological complication of liver disease that can ...
14 hours ago
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Cellular pathways may underlie some differences in physical fitness
Patterns of molecular activity in the blood may hold clues not only to how fit someone is, but also to the biological processes that support physical performance. Researchers at MIT, GE HealthCare, and the U.S. Military Academy ...
14 hours ago
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Fluorescent quail embryos could help solve serious birth defects in humans
The quail is a small, unassuming bird that glides rather than flies and prefers to hide under bushes than to perch on top of a tree. And now, it's also helping scientists understand serious birth defects in humans.
13 hours ago
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Experimental drug may restore movement after stroke
Every stroke begins with a sudden interruption of blood flow in the brain. But what happens afterward—why neurons continue to lose function and die over the following days—has remained one of the most important unanswered ...
15 hours ago
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Age, sex, and cancer type can influence risk of subsequent cancers among survivors
The risk of developing a subsequent primary cancer varied significantly by age at initial diagnosis, sex, and type of first cancer, according to a study by Oxana Palesh and Susan Hong and colleagues at Virginia Commonwealth ...
16 hours ago
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Adversity across life linked to greater frailty and faster biological aging
Published in BMC Medicine, the study analyzed data from over 150,000 participants and found the strongest associations in people who experienced adversity in both childhood and adulthood. These individuals were more frail ...
15 hours ago
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Scientists create first-ever 'smell map' of the nose's smell receptors
For most of us, the sense of smell is an integral part of everyday life; it plays a critical role in providing information about our surroundings, alerting us to potential dangers, enhancing our sense of taste, and evoking ...
19 hours ago
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Key molecular dynamic could boost cancer treatments while limiting stem cell transplant rejection
A key molecular dynamic could be the key to fighting tumors while allowing patients to still receive life-saving cell transplantation, according to the latest finding published by a team of scientists from the Hackensack ...
11 hours ago
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