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Brain immunity may undergo a major midlife overhaul linked to neuroinflammation
A new study indicates that the immune cell landscape of the hippocampus, a brain region critical for learning and memory, rapidly undergoes substantial remodeling beginning in midlife. This previously unrecognized shift suggests ...
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Dormant pigment cells found in vitiligo patches may offer treatment target
Vitiligo is an autoimmune disease in which the body's immune system attacks and destroys melanocytes, the cells that produce the skin pigment melanin. Once the melanocytes are gone, the skin turns white, leading to the characteristic ...
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Medical research news
Two new therapies and rapid tests could reshape drug-resistant gonorrhea care
Drug-resistant Neisseria gonorrhoeae (the bacterium that causes gonorrhea) has become one of the most urgent antimicrobial-resistant threats to public health worldwide. Clinicians expect to be confronted by rising rates of ...
1 hour ago
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Chemotherapy leaves detectable DNA fingerprints in childhood tumors within 18 months
Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids). ...
44 minutes ago
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Aspirin reverses diet-driven depression-like behavior in mice
Depression is among the most common psychiatric disorders, estimated to affect between 280 million and 332 million people worldwide. This disorder is characterized by persistent sadness and hopelessness, low energy, a loss ...
Gene activity in blood fluctuates more than expected—and that has consequences for medicine
Take a blood sample from someone in the dead of winter. Take another in midsummer. Same person, same laboratory. And yet, at the level of gene activity, the molecular picture can look surprisingly different. This is not an ...
1 hour ago
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Parents' socioeconomic status is more important than prenatal behaviors to a future child's health, study suggests
Family socioeconomic position may be a more important determinant of children's health than parental behaviors such as smoking, drinking or caffeine consumption, according to a study published in PLOS Medicine by Gemma Sharp ...
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How systemic immune regulation is 'hijacked' during tumor progression
The immune system plays a critical role in protecting the body from cancer by recognizing and eliminating abnormal cells before they can develop into tumors. This process relies on T cells that can recognize tumor-derived ...
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Traveling waves in rat brains give hints about information transfer in consciousness
How and why we experience consciousness is a question that has long plagued philosophers and scientists alike. We have come to understand that, when awake, our brains organize neural information for perception, yet we completely ...
2 hours ago
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Brain cancer map uncovers thousands of hidden targets for personalized immunotherapies
Researchers from the Clinical Neuroscience Consortium (CNC), a collaborative platform jointly established by the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and Queen Mary Hospital, in collaboration with ...
2 hours ago
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How the heart's 'little brain' helps it function and protects it against stress
For years, scientists have known that the heart has its own network of nerves, the intrinsic cardiac nervous system (ICNS), sometimes called its "little brain." Exactly how it functions has remained something of a mystery, ...
Gut microbiome reveals molecular clues to how quickly our bodies age
Researchers at the University of Hawaiʻi at Mānoa have found that certain gut bacteria are linked to how quickly the body ages, providing new insight into the connection between the gut, health and longevity.
3 hours ago
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Premature blood stem cell aging in sickle cell disease may be reversible
Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital. Patients with sickle ...
3 hours ago
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Living in a neighborhood with traffic noise may increase Parkinson's disease risk over time
Loud traffic noise has long been recognized as more than just a disturbance; it is a significant public health concern. Prolonged exposure to excessive traffic sounds can contribute to a range of health problems, including ...
A mother's devotion to newborns begins in the brain, study suggests
New research has found that a hormone is responsible for making mothers' interactions with newborns feel rewarding rather than just necessary. The University of Otago—Ōtākou Whakaihu Waka study, published in Science Advances, ...
3 hours ago
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Drug temporarily reverses autism-like brain changes in adult mice within hours
A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but those brain and behavioral effects may be rapidly, though temporarily, reversible in adulthood ...
10 hours ago
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Ancient molecule made inside tumors drives immune response, study finds
An ancient molecule that existed long before the circulatory system evolved has been found to support cancer immunotherapy. Researchers at Nagoya University in Japan found that complement C3 protein acts inside tumors to ...
4 hours ago
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Artery-on-a-chip helps predict stroke risk
Predicting an individual's risk of ischemic stroke is difficult because thrombosis embolization—the process of a blood clot detaching from the area where it formed, traveling and then sticking in another blood vessel—is based ...
4 hours ago
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New immune mechanism helps explain why ovarian cancer stops responding to chemotherapy
Scientists at The Wistar Institute have identified a new mechanism behind the chemotherapy resistance that makes ovarian cancer so lethal. In a new study published in The Journal for ImmunoTherapy of Cancer, the researchers ...
5 hours ago
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Study reveals how networks of switches in DNA, which regulate gene expression, drive cancer growth
Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated. Scientists know these switches play a critical role in cancer and other diseases, but they ...
7 hours ago
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