Oncology & Cancer

Germline testing underused in cancer patients

Few patients diagnosed with cancer between 2013 and 2019 in California and Georgia underwent germline testing, according to a study published online June 5 in the Journal of the American Medical Association to coincide with ...

Medical research

Why new cancer treatment discoveries are proliferating

In the five years since the FDA's initial approval of chimeric antigen receptor (CAR) T cell therapy, Penn Medicine has gleaned 20 additional approvals related to drugs and techniques to treat or detect cancer.

Genetics

New subtypes identified in difficult-to-treat ovarian cancer

Every year, approximately 400 women die of ovarian cancer in Finland, while the corresponding figure for Europe overall is more than 40,000. Ovarian cancer is a genetically very heterogeneous disease, which makes it exceptionally ...

Oncology & Cancer

Study links obesity with dampened immune detection of oral cancers

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the ...

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Ovarian cancer is a cancerous growth arising from the ovary. Symptoms are frequently very subtle early on and may include: bloating, pelvic pain, difficulty eating and frequent urination, and are easily confused with other illnesses.

Most (more than 90%) ovarian cancers are classified as "epithelial" and are believed to arise from the surface (epithelium) of the ovary. However, some evidence suggests that the fallopian tube could also be the source of some ovarian cancers. Since the ovaries and tubes are closely related to each other, it is thought that these fallopian cancer cells can mimic ovarian cancer. Other types may arise from the egg cells (germ cell tumor) or supporting cells. These cancers are grouped into the category of gynecologic cancer.

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