Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor that points at novel cancer biological mechanisms and possible ...
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A new colorectal cancer vaccine showed positive results in the phase 1 clinical trial to demonstrate that the approach is safe. The patients treated had no signs of serious adverse events and samples of their blood contained ...
3 hours ago
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Colorectal cancer is the second leading cause of cancer deaths in the U.S. and a growing problem around the world, but not because it's a particularly difficult cancer to detect and halt. The problem, doctors and researchers ...
Apr 22, 2019
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Genomic differences related to the immune system may play a key role in the early development of lung cancer. That finding, published April 23, 2019, in Nature Communications, reveals potential for developing new therapeutics ...
Apr 23, 2019
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Even after decades of research, cancer remains difficult to treat, in part because of its ability to evade the body's natural defenses found in the immune system.
Apr 22, 2019
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Dear Mayo Clinic: Are there ways to prevent colon cancer? What about early symptoms to watch for? I just turned 50, and I've heard colon cancer is more common as you get older. I'd like to lower my risk of getting this disease ...
Apr 11, 2019
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(HealthDay)—Colon cancer is highly preventable through regular screening. But the right type of screening depends on your particular risk factors, an expert says.
Mar 26, 2019
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If caught early, nearly all cases of colon cancer are curable. Though this should make screening tests straightforward, colon cancer screening suffers from a paradoxical combination of low compliance rates and overdiagnosis.
Apr 09, 2019
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Johns Hopkins Kimmel Cancer Center researchers say a new study of clusters of mouse cells known as "organoids" has significantly strengthened evidence that epigenetic changes, common to aging, play a essential role in colon ...
Apr 11, 2019
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The plant that adds flavor, color and bitterness to beer also produces a primary compound that thwarts cancer cells, and two important derivatives of the compound do as well, new research at Oregon State University shows.
Apr 02, 2019
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Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth. The resulting ...
Apr 11, 2019
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Starting routine colorectal cancer screening at age 45 rather than 50 would decrease U.S. cancer deaths by as much as 11,100 over five years, according to a new study led by researchers at the Stanford University School of ...
Mar 28, 2019
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Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre (CNIO), have published in Cancer Cell the results of a study that shows full regression of advanced ...
Apr 12, 2019
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A new study out today in Cancer Cell shows that blocking specific regions of a protein called UHRF1 switches on hundreds of cancer-fighting genes, impairing colorectal cancer cells' ability to grow and spread throughout the ...
Apr 04, 2019
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Levels of a gene that helps the immune system differentiate the good cells from the bad could be a good indicator of prognosis in people with colorectal cancers, Medical College of Georgia researchers report.
Apr 03, 2019
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Colorectal cancer, commonly known as bowel cancer, is a cancer from uncontrolled cell growth in the colon, rectum, or appendix. Symptoms typically include rectal bleeding and anemia which are sometimes associated with weight loss and changes in bowel habits.
Most colorectal cancer occurs due to lifestyle and increasing age with only a minority of cases associated with underlying genetic disorders. It typically starts in the lining of the bowel and if left untreated, can grow into the muscle layers underneath, and then through the bowel wall. Screening is effective at decreasing the chance of dying from colorectal cancer and is recommended starting at the age of 50 and continuing until a person is 75 years old. Localized bowel cancer is usually diagnosed through sigmoidoscopy or colonoscopy.
Cancers that are confined within the wall of the colon are often curable with surgery while cancer that has spread widely around the body is usually not curable and management then focuses on extending the person's life via chemotherapy and improving quality of life. Colorectal cancer is the fourth most commonly diagnosed cancer in the world, but it is more common in developed countries. Around 60% of cases were diagnosed in the developed world. It is estimated that worldwide, in 2008, 1.23 million new cases of colorectal cancer were clinically diagnosed, and that it killed 608,000 people.
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