Study shows that VEGF-A can increase expression of dopamine D2 receptors on endothelial cells
Researchers have identified a new molecular drug target that could result in new cancer drugs with fewer side effects.
May 20, 2022
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Researchers have identified a new molecular drug target that could result in new cancer drugs with fewer side effects.
May 20, 2022
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Published in Clinical Nutrition, researchers from the University of Minnesota Medical School looked at the production of colonic hydrogen sulfide—a toxic gas in the body that smells like rotten eggs—in people in response ...
May 03, 2022
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Researchers at the Case Western Reserve University School Medicine have found that combining two cancer drugs can be effective in treating a specific type of colorectal cancer, according to a new study published in Nature ...
May 02, 2022
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DEAR MAYO CLINIC: I'm 46 and had my first colonoscopy last month. The doctor said everything looked good, although he removed a few polyps. Can you explain what a colon polyp is and if should I be concerned?
Apr 25, 2022
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Artificial intelligence reduced by twofold the rate at which precancerous polyps were missed in colorectal cancer screening, reported a team of international researchers led by Mayo Clinic. The study is published in Gastroenterology.
Apr 18, 2022
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In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but also reduce immune system activity. In a new study, ...
Apr 14, 2022
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Colon cancer is one of the most common types of cancer. Particularly in advanced stages of disease, the treatment still largely relies on traditional chemotherapy. The new generation of cancer treatments, so-called immunotherapies, ...
Mar 31, 2022
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A little over a year ago, Shannon Gregg noticed she was going to the bathroom more frequently and decided to see a gastroenterologist.
Mar 30, 2022
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March is Colorectal Cancer Awareness Month, which makes this a good time to learn about treating colorectal cancer.
Mar 23, 2022
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A new paper in Nature Communications reveals new insights into adaptations made by cancer cells to rewire their metabolism to achieve growth and survive. Among the discoveries include a challenge to a well-known feature in ...
Mar 23, 2022
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Colorectal cancer, commonly known as bowel cancer, is a cancer from uncontrolled cell growth in the colon, rectum, or appendix. Symptoms typically include rectal bleeding and anemia which are sometimes associated with weight loss and changes in bowel habits.
Most colorectal cancer occurs due to lifestyle and increasing age with only a minority of cases associated with underlying genetic disorders. It typically starts in the lining of the bowel and if left untreated, can grow into the muscle layers underneath, and then through the bowel wall. Screening is effective at decreasing the chance of dying from colorectal cancer and is recommended starting at the age of 50 and continuing until a person is 75 years old. Localized bowel cancer is usually diagnosed through sigmoidoscopy or colonoscopy.
Cancers that are confined within the wall of the colon are often curable with surgery while cancer that has spread widely around the body is usually not curable and management then focuses on extending the person's life via chemotherapy and improving quality of life. Colorectal cancer is the fourth most commonly diagnosed cancer in the world, but it is more common in developed countries. Around 60% of cases were diagnosed in the developed world. It is estimated that worldwide, in 2008, 1.23 million new cases of colorectal cancer were clinically diagnosed, and that it killed 608,000 people.
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