Oncology & Cancer

Stemming colorectal cancer in Latin America

Little is known about colorectal cancer screening strategies throughout the Western Hemisphere, with the exception of the U.S. and Canada. In a recent study by Regenstrief Institute, Indiana University School of Medicine, ...

Oncology & Cancer

Five key facts about cancer

With nearly 10 million deaths and nearly 20 million new cases in 2022, cancer remains one of the world's biggest killers, according to a report on Thursday by the World Health Organization.

Oncology & Cancer

Cracking the code: How what you eat might affect your cancer risk

There is an unresolved debate about the extent to which the environment contributes to cancer risk. Although epidemiological studies suggest that environmental factors such as diet can certainly contribute, especially for ...

Oncology & Cancer

The role of fibronectin in BRAF-mutant thyroid cancer treatment

New research overseen by University of Colorado Cancer Center member Rebecca Schweppe, Ph.D., could lead to improved treatment for people with thyroid cancer characterized by a mutation in the BRAF gene—a mutation also ...

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Colorectal cancer, commonly known as bowel cancer, is a cancer from uncontrolled cell growth in the colon, rectum, or appendix. Symptoms typically include rectal bleeding and anemia which are sometimes associated with weight loss and changes in bowel habits.

Most colorectal cancer occurs due to lifestyle and increasing age with only a minority of cases associated with underlying genetic disorders. It typically starts in the lining of the bowel and if left untreated, can grow into the muscle layers underneath, and then through the bowel wall. Screening is effective at decreasing the chance of dying from colorectal cancer and is recommended starting at the age of 50 and continuing until a person is 75 years old. Localized bowel cancer is usually diagnosed through sigmoidoscopy or colonoscopy.

Cancers that are confined within the wall of the colon are often curable with surgery while cancer that has spread widely around the body is usually not curable and management then focuses on extending the person's life via chemotherapy and improving quality of life. Colorectal cancer is the fourth most commonly diagnosed cancer in the world, but it is more common in developed countries. Around 60% of cases were diagnosed in the developed world. It is estimated that worldwide, in 2008, 1.23 million new cases of colorectal cancer were clinically diagnosed, and that it killed 608,000 people.

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