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Parkinson's & Movement disorders news
Neuroscience
Receptor structure reveals novel drug design opportunities for Parkinson's disease
University of Southern California-led researchers have discovered the structural details of a brain receptor called GPR6, which could lead to new treatments for Parkinson's disease.
Dec 5, 2024
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Parkinson's & Movement disorders
Wearable devices can help predict 5-year risk of falls for people with Parkinson's disease
A new study from the University of Oxford demonstrates how clinicians could use data to predict the risk of falls in people with Parkinson's disease (PD) to help improve effective longer term care planning.
Dec 5, 2024
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Research reveals possible link between protein G3BP1 and amyotrophic lateral sclerosis
Researchers from the Structural Biology Brussels group at Vrije Universiteit Brussel (VUB) have uncovered a significant mechanism that may contribute to amyotrophic lateral sclerosis (ALS), a disease that causes muscle weakness ...
Dec 5, 2024
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Common heart drug may slow progression of Huntington's disease
A common heart drug may slow the progression of Huntington's disease (HD), according to a new study by University of Iowa Health Care researchers.
Dec 2, 2024
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Chemical tag to investigate 'disordered' proteins sheds new light on Parkinson's research
Scientists at La Trobe University have created a world-first method to investigate "disordered" proteins in living cells, in research that could change how we understand and treat Parkinson's disease.
Nov 26, 2024
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New biomarkers could improve diagnosis and tracking of Parkinson's disease and Lewy body dementia
Investigators led by Tanya Simuni, MD, the Arthur C. Nielsen, Jr., Research Professor of Parkinson's Disease and Movement Disorders, have defined new biologic and clinical biomarkers for better identifying patients with different ...
Nov 26, 2024
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Digital therapeutics can improve Parkinson's control, study finds
The use of PD Neurotechnology's pioneering telemonitoring device to assess Parkinson's Disease (PD) symptoms and inform medication adjustments led to the majority of patients exhibiting improved or stable symptom manifestation, ...
Nov 26, 2024
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Network theory insights lead to a mathematical representation of Parkinson's disease
Neurodegenerative diseases, such as Parkinson's disease, can be thought of as arising from malfunctions in the network of neuronal agglomerates in the brain. It is therefore often useful to apply insights from a branch of ...
Nov 22, 2024
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Parkinson's drug changes the gut microbiome for the worse due to iron deficiency, study reveals
A new study has revealed that the widely prescribed Parkinson's disease drug entacapone significantly disrupts the human gut microbiome by inducing iron deficiency.
Nov 21, 2024
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Algorithm can identify subtle changes in a person's voice for early Parkinson's detection
Algorithms that can detect subtle changes in a person's voice are emerging as a potential new diagnostic tool for Parkinson's disease, according to researchers from Iraq and Australia.
Nov 21, 2024
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Deep brain stimulation: A promising future for anxiety in Parkinson's patients
Deep brain stimulation has revealed that a specific type of brain wave activity is associated with levels of anxiety in people living with Parkinson's disease, according to research led by scientists at City St George's and ...
Nov 20, 2024
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PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia
A recently published study by researchers at the University of Arizona Health Sciences found that a tiny protein called PNA5 appears to have a protective effect on brain cells, which could lead to treatments for the cognitive ...
Nov 19, 2024
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Reframing cerebral palsy as a lifelong physical disability could improve adult care, researchers say
In the United States, there are currently more adults living with cerebral palsy than children. Despite this, the Centers for Disease Control and Prevention still label cerebral palsy as "the most common motor disability ...
Nov 19, 2024
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Parkinson's paradox: When more dopamine means more tremor
Researchers from the Champalimaud Foundation have shed light on the puzzling relationship between dopamine and rest tremor in Parkinson's disease, finding that preserved dopamine in certain brain regions may actually contribute ...
Nov 18, 2024
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Gene therapy protects against motor neuron disease in rats
University of Wisconsin–Madison researchers targeting a group of hereditary neurodegenerative diseases have found success using a gene therapy treatment in an animal model. The approach, which uses CRISPR-Cas9 genome editing ...
Nov 12, 2024
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Researchers identify a potential biomarker of Parkinson's disease progression
A team of researchers from the University of Barcelona and the Bellvitge Biomedical Research Institute (IDIBELL) has identified a potential biomarker of Parkinson's disease progression. According to the study, published in ...
Nov 12, 2024
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Protein variant presents a potential new target for developing effective treatments for Parkinson's disease
Researchers at Tel Aviv University (TAU) discovered a new factor in the pathology of Parkinson's disease, which in the future may serve as a target for developing new treatments for this terrible ailment, affecting close ...
Nov 12, 2024
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Key pathway leading to neurodegeneration in early stages of ALS identified
Approximately 5,000 people in the U.S. develop amyotrophic lateral sclerosis (ALS) each year. On average, they survive for only two to five years after being diagnosed, according to the Centers for Disease Control and Prevention.
Nov 8, 2024
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New Huntington's treatment prevents protein aggregation
Scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington's disease, an incurable, debilitating illness that causes nerve cells to break down in the ...
Nov 1, 2024
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Precision diagnostics close in on Parkinson's disease proteins in extracellular vesicles
Brain disorders like Parkinson's disease (PD) or Alzheimer's disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even ...
Nov 1, 2024
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RNA structures present a promising target for early intervention in Parkinson's disease
A team of researchers at Kumamoto University has uncovered a mechanism in the formation of harmful protein aggregates that lead to neurodegenerative diseases such as Parkinson's disease.
Nov 1, 2024
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Glaucoma drug shows promise against neurodegenerative diseases, animal studies suggest
A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of the protein tau, which causes various forms of dementia and is implicated in Alzheimer's disease.
Oct 31, 2024
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Study identifies 51 amyotrophic lateral sclerosis-associated mutations that could help diagnose the disease
Using sequencing techniques, researchers associated 51 mutations in mitochondrial DNA with amyotrophic lateral sclerosis (ALS), an incurable degenerative neurological disorder that leads to muscle atrophy and paralysis. Thirteen ...
Oct 31, 2024
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Rapid horizontal eye movement can improve stability in people with Parkinson's
Rapid side-to-side eye movements can help stabilize posture, avoid falls and maintain balance for people with Parkinson's disease, just as they can for healthy people. This seemingly counterintuitive conclusion was reached ...
Oct 30, 2024
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Discovery of key mechanism in Huntington's disease could pave the way for early detection and treatment
Researchers from the University of Oxford have identified a key biochemical mechanism relevant to the development of Huntington's disease. This discovery opens up the possibility of studying the disease before its clinical ...
Oct 28, 2024
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