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Parkinson's & Movement disorders news

Neuroscience

Altered brain activity patterns of Parkinson's captured in mice

The tell-tale tremors of Parkinson's disease emerge from abnormal activity in a brain region crucial for voluntary movement. Using a mouse model of the disease, researchers at the Okinawa Institute of Science and Technology ...

Parkinson's & Movement disorders

Neuromelanin-sensitive MRI identified as a potential biomarker for psychosis

Researchers have shown that a type of magnetic resonance imaging—called neuromelanin-sensitive MRI (NM-MRI)—is a potential biomarker for psychosis. NM-MRI signal was found to be a marker of dopamine function in people ...

Neuroscience

Intervening in glial cells protects neurons in Parkinson's model

Loss of dopaminergic neurons is a hallmark of Parkinson's disease pathology. When dopaminergic neurons are stressed, they send out a call for help to nearby glial cells that are tasked with providing neuronal support, protection ...

Parkinson's & Movement disorders

The involvement of the gut in Parkinson's disease: hype or hope?

There is growing evidence that at least in some patients with Parkinson's disease (PD), the disease may begin in the gut. Writing in a special supplement to the Journal of Parkinson's Disease, experts explore the last two ...

Parkinson's & Movement disorders

Levodopa + carbidopa does not modify disease in early Parkinson

(HealthDay)—For patients with early Parkinson disease, treatment with levodopa combined with carbidopa has no disease-modifying effect, according to a study published in the Jan. 24 issue of the New England Journal of Medicine.

Medications

How gut bacteria affect the treatment of Parkinson's disease

Patients with Parkinson's disease are treated with levodopa, which is converted into dopamine, a neurotransmitter in the brain. In a study published on 18 January in the journal Nature Communications, scientists from the ...

Parkinson's & Movement disorders

Defective glial cells can push neurons toward Parkinson's disease

Researchers from the University of Barcelona have shown that defective versions of human brain cells called astrocytes are linked to the buildup of a toxic protein that is the hallmark of Parkinson's disease. The studied ...

Parkinson's & Movement disorders

Scientists uncover how protein clumps damage cells in Parkinson's

Biologists studying Parkinson's disease have long hoped to solve the mystery of the telltale "clumps." Scientists want to know how clumps of misfolded proteins damage brain cells and contribute to the disease.

Parkinson's & Movement disorders

Parkinson's disease experts devise a roadmap

A recently discovered protein, alpha-synuclein, has become one of the most attractive targets for developing new drugs with the potential to slow down or arrest the progression of Parkinson's disease (PD). Experts in the ...