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Parkinson's & Movement disorders news

Neuroscience

Can deep sleep help devastating brain disorders? Scientists studying Parkinson's want to find out

Sleep may be one of the most potent medicines for the brain, scientists are discovering, as they explore the inner labyrinths of the three-pound organ during deep sleep and dream cycles in both health and disease.

Neuroscience

Flavonoids may reduce mortality risk for people with Parkinson's disease

People with Parkinson's disease who eat more flavonoids—compounds found in richly colored foods like berries, cocoa and red wine—may have a lower mortality risk than those who don't, according to a new study.

Parkinson's & Movement disorders

Study: Get moving to put the brakes on early Parkinson's

A new study suggests that people with early-stage Parkinson's disease who regularly got one to two hours of moderate exercise twice a week, like walking or gardening, may have less trouble balancing, walking and doing daily ...

Medical research

Study details lessons learned from remote clinical studies

Traditional, in-person clinical research studies have long been plagued by slow and often unsuccessful recruitment. The limits of site location, which sometimes requires participants to travel long distances, and the reliance ...

Neuroscience

Dementia protein changes discovered in terminal childhood disease

In a world-first, researchers at Newcastle University have found that the brains of infants who sadly passed away with an extremely rare genetic condition, Krabbe disease, have similar changes to those seen in two age-related ...

Medical research

Transforming 'undone science' into 'done science'

Mannitol, a natural sweetener, may help treat Parkinson's disease, yet was not being tested in clinical trials. The story of mannitol is one of many examples of "undone science": research questions unfunded or ignored for ...

Parkinson's & Movement disorders

Parkinson's disease mutation misdirects iron in the brain

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National ...

Parkinson's & Movement disorders

Protein test could lead to earlier and better diagnosis of Parkinson's

Scientists at the Oxford Parkinson's Disease Centre (OPDC) have been able to use a highly-sensitive method called α-synuclein real-time quaking-induced conversion (αSyn-RT-QuIC) to observe the clumping of alpha-synuclein ...

Parkinson's & Movement disorders

Are scientists homing in on a cure for Parkinson's disease?

A molecule that shows promise in preventing Parkinson's disease has been refined by scientists at the University of Bath in the UK, and has the potential to be developed into a drug to treat the deadly neurodegenerative disease.

Parkinson's & Movement disorders

Study: People with Parkinson's may speak up to 60% less

Parkinson's disease can disrupt multiple aspects of a person's functioning, including the volume, rhythm and intonation of their speech. In some cases, a person with Parkinson's will hesitate to speak or pause when speaking, ...

Genetics

Gene therapy boosts Parkinson's disease drug benefits

In late-stage Parkinson's disease, the drug levodopa becomes less effective in treating symptoms because of the inexorable loss of dopamine-releasing neurons. But a new Northwestern Medicine preclinical study shows a gene ...

Neuroscience

Study: Death rate from Parkinson's rising in US

A new study shows that in the last two decades the death rate from Parkinson's disease has risen about 63% in the United States. The research is published in the October 27, 2021, online issue of Neurology, the medical journal ...

Neuroscience

Research shows promising results for Parkinson's disease treatment

Researchers from Carnegie Mellon University have found a way to make deep brain stimulation (DBS) more precise, resulting in therapeutic effects that outlast what is currently available. The work, led by Aryn Gittis and colleagues ...

Neuroscience

Neuroscientists map major circuit in the mouse brain

A UCLA study using mice reveals new insights into the wiring of a major circuit in the brain that is attacked by Parkinson's and Huntington's disease. The findings could hone scientists' understanding of how these disorders ...

Neuroscience

Immune cells in the brain share the work

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases ...

Parkinson's & Movement disorders

People with Parkinson's may benefit from 7 walking strategies

Various strategies can help people with Parkinson's who have difficulty walking, but a new study finds that many people have never heard of or tried these strategies. The research is published in the September 8, 2021, online ...

Alzheimer's disease & dementia

New information on the early stages of dementia with Lewy bodies

Results obtained in a study recently completed at the University of Helsinki and Helsinki University Hospital reinforce the notion that dementia with Lewy bodies can be pathologically classified into two different disease ...

Medical research

Identification of bacterial proteins that promote neurodegeneration

Growing evidence indicates that gut microbiota plays a critical role in regulating the progression of neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease (AD), but the molecular mechanism underlying ...