Researchers in a multi-institution study led by UCLA Health have identified several overlooked issues affecting women with Parkinson's Disease (PD) and call for more research, customized treatments, education and support ...
Jan 21, 2022
A team of University of California, Irvine researchers has discovered a possible reason why L-dopa, the front-line drug for treating Parkinson's disease, loses efficacy and causes dyskinesia—involuntary, erratic muscle ...
Jan 20, 2022
New findings provide a better understanding of how the synthesis of dopamine is regulated in the brain. It may shed new light on the mechanism behind diseases such as Parkinson's.
Jan 12, 2022
A new study suggests that people with early-stage Parkinson's disease who regularly got one to two hours of moderate exercise twice a week, like walking or gardening, may have less trouble balancing, walking and doing daily ...
Jan 12, 2022
Traditional, in-person clinical research studies have long been plagued by slow and often unsuccessful recruitment. The limits of site location, which sometimes requires participants to travel long distances, and the reliance ...
Jan 11, 2022
In a world-first, researchers at Newcastle University have found that the brains of infants who sadly passed away with an extremely rare genetic condition, Krabbe disease, have similar changes to those seen in two age-related ...
Jan 10, 2022
Dopamine agonists and dopamine reuptake inhibitors provide similar quality of life for Parkinson disease patients
For patients with Parkinson disease on levodopa therapy, patient-rated quality of life is similar for those receiving adjuvant therapy with dopamine agonists compared with dopamine reuptake inhibitors (DRIs); and among DRIs, ...
Dec 29, 2021
Researchers have solved a decade-long mystery about a critical protein linked to Parkinson's disease that could help to fast-track treatments for the incurable disease.
Dec 23, 2021
Mannitol, a natural sweetener, may help treat Parkinson's disease, yet was not being tested in clinical trials. The story of mannitol is one of many examples of "undone science": research questions unfunded or ignored for ...
Dec 22, 2021
A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National ...
Dec 16, 2021
Scientists at the Oxford Parkinson's Disease Centre (OPDC) have been able to use a highly-sensitive method called α-synuclein real-time quaking-induced conversion (αSyn-RT-QuIC) to observe the clumping of alpha-synuclein ...
Dec 15, 2021
Case reports of relatively young COVID-19 patients who developed Parkinson's disease within weeks of contracting the virus have led scientists to wonder if there could be a link between the two conditions. Now, researchers ...
Dec 14, 2021
Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.
Dec 13, 2021
A molecule that shows promise in preventing Parkinson's disease has been refined by scientists at the University of Bath in the UK, and has the potential to be developed into a drug to treat the deadly neurodegenerative disease.
Dec 09, 2021
Whether or not someone develops Parkinson's disease may be a game of nanometers.
Dec 08, 2021
Parkinson's disease can disrupt multiple aspects of a person's functioning, including the volume, rhythm and intonation of their speech. In some cases, a person with Parkinson's will hesitate to speak or pause when speaking, ...
Dec 03, 2021
A new study from Texas Biomedical Research Institute (Texas Biomed) and collaborators has identified a promising drug candidate to minimize uncontrolled, erratic muscle movements, called dyskinesia, associated with Parkinson's ...
Dec 01, 2021
A new combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson's disease-afflicted brain cells, according to a Northwestern Medicine study published in Neuron.
Nov 24, 2021