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Parkinson's & Movement disorders news
Genetics
Key genes in Parkinson's disease discovered using CRISPR technology
A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that increase their risk of PD go on to develop the disease, while others who also carry such variants do not. ...
Apr 11, 2025
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Parkinson's & Movement disorders
RNA-based blood test identifies Parkinson's before symptoms appear
Researchers have developed a simple and cost-effective blood test capable of detecting Parkinson's disease long before symptoms emerge, comparing the current state of diagnosing neurodegenerative diseases to the fight against ...
Apr 11, 2025
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Discovery of α-synuclein's 'fuzzy coat' mechanism offers new insights into Parkinson's
Parkinson's disease (PD) and Lewy body dementia (LBD) are incurable and progressive neurodegenerative disorders, with some overlapping symptoms. An estimated 10 million people worldwide live with PD, while the figure for ...
Apr 11, 2025
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Discovery reveals protein involved in Parkinson's disease also drives skin cancer
A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, new research led by Oregon Health & Science University finds.
Apr 9, 2025
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Parkinson's disease researchers develop cellular 'invisibility cloak' to protect neural grafts
Florey researchers have engineered a way to fool the immune system into accepting neural grafts as part of the body, rather than attacking them as foreign objects.
Apr 9, 2025
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Early Parkinson's symptoms often mistaken for normal aging
Parkinson's disease is often seen as a condition that primarily affects older adults. In reality, it can impact people at any age, with 10–20% of cases appearing before the age of 50, and about half of those are diagnosed ...
Apr 9, 2025
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Tavapadon as adjunct to levodopa increases daily ON time in Parkinson's disease
For patients with Parkinson's disease with motor fluctuations, the oral once-daily, selective D1/D5 partial dopamine agonist tavapadon as an adjunct to levodopa increases total daily ON time versus placebo, according to a ...
Apr 8, 2025
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The brain's own repair mechanism: New neurons may reverse damage in Huntington's disease
New research shows that the adult brain can generate new neurons that integrate into key motor circuits. The findings demonstrate that stimulating natural brain processes may help repair damaged neural networks in Huntington's ...
Apr 7, 2025
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Diagnostic uncertainty in Parkinson's disease: New study calls for improved diagnostic processes
A new study by the University of Turku and Turku University Hospital, Finland, found that a significant proportion of Parkinson's disease diagnoses are later corrected. Up to one in six diagnoses changed after 10 years of ...
Apr 7, 2025
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Six Parkinson's disease facts
Brought into the limelight by actor Michael J. Fox, Parkinson's disease affects the body's ability to control movement.
Apr 7, 2025
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Parkinson's protein clumps in heart nerves could offer new treatment path
Parkinson's doesn't just affect movement and the brain—it may also impact the heart, according to new research from the University of Surrey. Scientists from Surrey's School of Veterinary Medicine suggest that targeting ...
Apr 3, 2025
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New Parkinson's treatment could help millions
After a twitching pinky finger led to a diagnosis of young-onset Parkinson's disease, Keith Krehbiel, then 42, stopped at a bookstore on the way home to learn more about the progressive neurological disorder before telling ...
Mar 24, 2025
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Renewal processes in the cell: Disruptions favor diseases such as Alzheimer's and Parkinson's, study finds
In an international research collaboration involving the University Medical Center Göttingen (UMG), researchers have produced the most complete map to date of how long different proteins persist in many tissues of the body. ...
Mar 21, 2025
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AI-driven MRI analysis improves accuracy in distinguishing Parkinsonian disorders
University of Florida researchers have led a multicenter study demonstrating that Automated Imaging Differentiation for Parkinsonism (AIDP), a machine-learning method using magnetic resonance imaging (MRI), accurately distinguishes ...
Refined test could improve Parkinson's disease diagnosis
A team that includes a RIKEN researcher has refined a lab test for measuring protein aggregate levels in samples from patients with certain neurodegenerative diseases. This has the potential to improve diagnosis and drug ...
Mar 19, 2025
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Treatment for Parkinson's disease and restless leg syndrome is linked with risky behavior
Getting a headache and feeling sick are common side-effects for many medicines. Indulging in risky sexual behavior or pathological gambling—not so common.
Mar 17, 2025
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Scientists solve decades-long Parkinson's mystery
WEHI researchers have made a huge leap forward in the fight against Parkinson's disease, solving a decades-long mystery that paves the way for the development of new drugs to treat the condition.
Mar 13, 2025
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ITSN1 gene linked to substantial risk of Parkinson's disease
A new study published in Cell Reports reveals a breakthrough discovery linking genetic variants in the gene ITSN1 to a significantly elevated risk of Parkinson's disease, a neurodegenerative condition that affects nearly ...
Mar 7, 2025
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Cases of Parkinson's disease set to reach 25 million worldwide by 2050, study suggests
By 2050, there will be 25.2 million people living with Parkinson's disease worldwide (a 112% increase from 2021), largely due to population aging, suggests a modeling study published by The BMJ.
Mar 5, 2025
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Understanding how metabolism contributes to Parkinson's disease
Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's disease, according to a study published in Nature Communications.
Mar 4, 2025
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Sleep apnea linked to increased risk of Parkinson's: Study suggests CPAP may reduce risk
People with obstructive sleep apnea have an increased risk of Parkinson's disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study presented at ...
Mar 2, 2025
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Blood test could lead to better diagnosis and management of ALS
ALS, or amyotrophic lateral sclerosis, can sometimes be difficult to diagnose or to predict how quickly the disease is likely to progress. A new study helps determine which blood tests are best at identifying and monitoring ...
Feb 26, 2025
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Men's immune response to brain protein may explain their higher rates of Parkinson's disease
Scientists at La Jolla Institute for Immunology (LJI) have found a potential new target for treating Parkinson's disease. Their new research reveals how a protein in brain cells may drive Parkinson's onset—and offers a ...
Feb 25, 2025
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Studies of Parkinson's disease have long overlooked Pacific populations—meta-analysis shows why that must change
A form of Parkinson's disease caused by mutations in a gene known as PINK1 has long been labeled rare. But our research shows it's anything but—at least for some populations.
Feb 25, 2025
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Platform trials streamline ALS therapy evaluation by rapidly ruling out ineffective drugs
Massachusetts General Hospital coordinated the first four platform trials within the HEALEY ALS platform to evaluate potential treatments for amyotrophic lateral sclerosis (ALS), with results published in various JAMA journals.
